2000, Volume 2, Issue 6
Strategic Study of CAE >> 2000, Volume 2, Issue 6
Biomimetic Design of Biomaterials
Research Institute of Polymer Materials , Tianjin University , Tianjin 300072, China
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Abstract
The research on biomaterials has gotten achievements during the past 30 years. However, few kinds of them are well accepted clinically. Even those implanted in vivo for long time are considered to be exotic things by bodies. It prompts people to design biomaterials through biomimetic approaches. This paper overviews the design of artificial extracellular matrixes and the control of apoptosis based on the interaction between biomaterials and protein, saccharide and DNA. In view of the broadness and flexibility life science, it is recommended to design the biomaterials on cellular and molecular levels to enhance the affinity of biomaterials and host, and to promote the development of intelligent and environment-friendshiply biomaterials.
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References
[ 1 ] HorwitzAF .Integrinsandhealth [J] .ScientificAmerican , 1 997, 2 77 (5) :68～ 75
[ 2 ] KimBS , MooneyDJ.Developmentofbiocompatiblesyntheticextracellularmatericesfortissueengineering[J] .TrendinBiotechmology, 1 998, 1 6 (5) :2 2 4～ 2 2 9
[ 3 ] RouhiAM .ContemporaryBiomaterials.ChemEngNews , 1 999, 77 (3) :51～ 59
[ 4 ] YinYJ, YaoKD , ChengGX , etal.Propertiesofpolyelectrolytecomplexfilmsofchitosanand gelatin[J] .PolymerInternational, 1 999, 48 (6) :42 9～432
[ 5 ] 村田れ一 , 大内辰郎 DNA搬运机能を有するキ卜ニ诱导体 [J] .高分子 , 1 997, 45 (6) :339
[ 6 ] 梅野太甫 , 前田瑞夫 机功性DNAの合成と应用 .高分子 , 1 997, 46 (5) :31 4～ 31 8
[ 7 ] 西则雄 , 北村秀光 素材としこDNA [J] .高分子 , 1 998, 47 (6) :398～ 40 1
[ 8 ] WilsenEK , DNA’sConductancestillconfounds[J] .ChemEngNews, 1 998, 2 7:51～ 54
[ 9 ] FinkHW , SchonenbergerC .ElectricalconductionthroughDNAmolecules [J] .Nature , 1 999, 398 (672 8) :40 7～ 41 0
[10] IngberDE .Thearchitectureoflife [J] .ScientificAmerican , 1 998, 2 78:1 330～ 1 339
[11] WhitesidesGM .Self ammsemblingmaterial [J] .ScientificAmerican , 1 995 , 2 73 (3) :1 1 4～ 1 1 7
[12] 赤池敏宏 ハイアリツレ材料 (软组织 ) 金属1998 , 68 (3) :1 95～ 2 0 2
[13] KimBS , MooneyDJ .Developmentofbiocompatibleextracellularmatricesfortissueengineering [J] .TrendsinBiotechnology, 1 998, 1 6 (5) :2 2 4～ 2 30
[14] MaoChuanbin , LiHengde, CuiFuzhai, etal.Biomimeticgrowthofcalcium phosphateswithanor ganizedhydroxylatedsurfaceastemplate [J] .JournalofMaterialsScienceLetters, 1 998, 1 7 (1 7) :1 4 79～ 1 4 81
[15] 杜昶 , 崔福斋 , 李恒德 纳米晶羟基磷灰石 /胶原仿骨材料的细胞反应 [C] .北京 :中国材料研讨会论文摘要集 1 998, 62 3
[16] ShiYB , LiQ , DamjanouskiS , etal.IntJMolMed . 1 998, 2 :2 73～ 2 82
[17] AoshibaK , RenuardSI, SpurzemJR .Cell matrixandcell cellinteactionsmodulateapoptosisofbronchialepithellialcells [J] .Am .J .Physiol., 2 72 (LungCellMol.Physiol, 1 6 , L2 8-L37 (1 997)
[18] DaniellH .GudaC .Biopolymerproductioninmicroa ganismsandplants [J] .Chem .&Ind ., 1 997, 7:555～ 558
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