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2021, Vol.15, Issue.4

Contents Volume 15 · Issue 4 · 2021. Pages 507-648 13 articles

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REVIEW

Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 507-527 doi:10.1007/s11684-020-0814-5

Abstract 201 PDF 3

Translational application of neuroimaging in major depressive disorder: a review of psychoradiological studies

Ziqi Chen, Xiaoqi Huang, Qiyong Gong, Bharat B. Biswal

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 528-540 doi:10.1007/s11684-020-0798-1

Abstract 220 PDF 2

Targeting “undruggable” c-Myc protein by synthetic lethality

Chen Wang, Hui Fang, Jiawei Zhang, Ying Gu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 541-550 doi:10.1007/s11684-020-0780-y

Abstract 332 PDF 3

Intratumor heterogeneity, microenvironment, and mechanisms of drug resistance in glioma recurrence and evolution

Zhaoshi Bao, Yongzhi Wang, Qiangwei Wang, Shengyu Fang, Xia Shan, Jiguang Wang, Tao Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 551-561 doi:10.1007/s11684-020-0760-2

Abstract 297 PDF 15

Clinical applications of neurolinguistics in neurosurgery

Peng Wang, Zehao Zhao, Linghao Bu, Nijiati Kudulaiti, Qiao Shan, Yuyao Zhou, N. U. Farrukh Hameed, Yangming Zhu, Lei Jin, Jie Zhang, Junfeng Lu, Jinsong Wu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 562-574 doi:10.1007/s11684-020-0771-z

Abstract 312 PDF 6

Advances in tissue state recognition in spinal surgery: a review

Hao Qu, Yu Zhao

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 575-584 doi:10.1007/s11684-020-0816-3

Abstract 271 PDF 11

RESEARCH ARTICLE

Cohort study of patients with Stevens–Johnson syndrome and toxic epidermal necrolysis in China: evaluation of risk models and new predictor of pulmonary consolidation on computed tomography

Yanhong Shou, Lu Yang, Yongsheng Yang, Xiaohua Zhu, Feng Li, Bo Yin, Yingyan Zheng, Jinhua Xu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 585-593 doi:10.1007/s11684-020-0817-2

Abstract 141 PDF 3

Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity

Nan Qin, Guang Xu, Yan Wang, Xiaoyan Zhan, Yuan Gao, Zhilei Wang, Shubin Fu, Wei Shi, Xiaorong Hou, Chunyu Wang, Ruisheng Li, Yan Liu, Jiabo Wang, Haiping Zhao, Xiaohe Xiao, Zhaofang Bai

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 594-607 doi:10.1007/s11684-020-0809-2

Abstract 299 PDF 13

Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated gene expression in t(8;21) acute myeloid leukemia

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi:10.1007/s11684-021-0836-7

Abstract 178 PDF 8

Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breast cancer was similar in node-negative diseases: a single-center study of 800 patients

Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 621-628 doi:10.1007/s11684-020-0738-0

Abstract 251 PDF 4

Comparison of the clinical features and therapeutics of COVID-19 in cardio-cerebrovascular disease (CCVD) and non-CCVD patients

Yu Wang, Lan Li, Yuanjiang Pan, Yu He, Zuhua Chen, Yunhao Xun, Yuhan Xu, Yilei Guo, Jiehong Yang, Jianchun Guo, Haitong Wan

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 629-637 doi:10.1007/s11684-020-0825-2

Abstract 178 PDF 6

LETTER TO FRONTIERS OF MEDICINE

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 638-643 doi:10.1007/s11684-021-0831-z

Abstract 179 PDF 2

Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections

Rongtao Lai, Tianhui Zhou, Xiaogang Xiang, Jie Lu, Haiguang Xin, Qing Xie

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 644-648 doi:10.1007/s11684-021-0847-4

Abstract 272 PDF 4