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Influenza's Plummeting during the COVID-19 Pandemic: The Roles of Mask-Wearing, Mobility Change, and SARS-CoV-2-2 Interference Article

Shasha Han, Ting Zhang, Yan Lyu, Shengjie Lai, Peixi Dai, Jiandong Zheng, Weizhong Yang, Xiao-Hua Zhou, Luzhao Feng

Engineering 2023, Volume 21, Issue 2,   Pages 195-202 doi: 10.1016/j.eng.2021.12.011

Abstract: mask-wearing, mobility changes (international and domestic), and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) interference in China, England, and the United States.Only in 2019–2020, SARS-CoV-2 interference had statistically significant effects.

Keywords： Influenza     Mask-wearing     Mobility mitigation     SARS-CoV-2 interference     Non-pharmaceutical interventions    

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ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 603-622 doi: 10.15302/J-FASE -2021397

Abstract:

The COVID-19 infections caused by SARS-CoV-2 have resulted in millions of people being infected andDespite possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection hasThis review also provides a new insight into the cellular and molecular alterations which have made SARS-CoV-2-2 self-modified with diversified infection patterns.

Keywords： profiling of bacteriocins / antiviral therapeutics / immunomodulation / nanosensor technology / mutated SARS-CoV-2bacteriocins / antiviral therapeutics / immunomodulation / nanosensor technology / mutated SARS-CoV-2    

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Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination

Frontiers of Medicine   Pages 747-757 doi: 10.1007/s11684-022-0954-x

Abstract: Emerging SARS-CoV-2 variants have made COVID-19 convalescents susceptible to re-infection and have raised, and 18.5 (Visit 3) months after SARS-CoV-2 infection.Similarly, the responses of SARS-CoV-2 RBD-specific B cells and memory B cells were boosted by the secondof the inactivated vaccine (one or two doses), which enhanced neutralization against highly mutated SARS-CoV-2-2 variants and memory B cell responses.

Keywords： COVID-19 convalescent     SARS-CoV-2     inactivated vaccination     neutralizing antibody     B cell response    

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Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections

Rongtao Lai, Tianhui Zhou, Xiaogang Xiang, Jie Lu, Haiguang Xin, Qing Xie

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 644-648 doi: 10.1007/s11684-021-0847-4

Abstract: development of a broadly neutralizing antibody against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is one of the attractive treatment strategies for COVID-19.receptor-binding domain (RBD) of the spike (S) protein is the main target of neutralizing antibodies when SARS-CoV-2-2 enters human cells through an interaction between the S protein and the angiotensin-converting enzyme2 expressed on various human cells.

Keywords： neutralizing antibody     antibody cocktail     SARS-CoV-2     COVID-19     therapeutic strategy    

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SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 185-195 doi: 10.1007/s11684-021-0913-y

Abstract: The record speed at which Chinese scientists identified severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) and shared its genomic sequence with the world, has greatly facilitated the developmentFurther research should be undertaken to develop more effective vaccines against SARS-CoV-2 variants

Keywords： COVID-19     pandemics     SARS-CoV-2     vaccination    

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Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 816-819 doi: 10.1007/s11684-020-0823-4

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Less attention paid to waterborne SARS-CoV-2 spreading in Beijing urban communities

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-021-1398-2

Abstract:

• A survey on individual’s perception of SARS-CoV-2 transmission was

Keywords： Environmental dissemination     Risk communication     Individual perception    

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SARS-CoV-2 variants, immune escape, and countermeasures

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 196-207 doi: 10.1007/s11684-021-0906-x

Abstract: SARS-CoV-2 variants have aroused great concern and are expected to continue spreading.

Keywords： SARS-CoV-2     COVID-19     vaccine     immune escape     breakthrough     prevention    

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Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from

Zhengqian Li, Taotao Liu, Ning Yang, Dengyang Han, Xinning Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbing Xiang, Xiangyang Guo

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 533-541 doi: 10.1007/s11684-020-0786-5

Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2-2), has caused a global pandemic in only 3 months.respiratory distress, characteristic neurological manifestations are also described, indicating that SARS-CoV-2-2 may be an underestimated opportunistic pathogen of the brain., laryngopharynx, trachea, lower respiratory tract, alveoli epithelium, or gastrointestinal mucosa, SARS-CoV-2

Keywords： coronavirus disease 2019 (COVID-19)     SARS-CoV-2     neurological manifestations     neuroinvasion     brain    

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Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection

Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 746-751 doi: 10.1007/s11684-020-0822-5

Abstract: (SARS-CoV-2).How long the adaptive immunity triggered by SARS-CoV-2 can last is of critical clinical relevance inAll samples were positive for IgGs against the S- and N-proteins of SARS-CoV-2.for memory T-cell tests, we found that interferon γ-producing CD4 and CD8 cells were increased upon SARS-CoV-2Together, these results indicate that durable anti-SARS-CoV-2 immunity is common in convalescent population

Keywords： SARS-CoV-2     neutralizing antibodies     T-cell response    

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Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective

Frontiers of Medicine doi: 10.1007/s11684-023-0995-9

Abstract: Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of inactivatedWe compared the risk of SARS-CoV-2 infection after complete vaccination with Sinopharm/BBIBP in peopleprimary series of vaccination with Sinopharm/BBIBP in Bangkok, Thailand were prospectively followed for SARS-CoV-2-2 infection through text messaging and telephone interviewing for 6 months.The protection against SARS-CoV-2 infection of the Sinopharm vaccine was similar in participants with

Keywords： COVID-19     Sinopharm/BBIBP vaccine     immunocompromised patients     real-world    

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SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world, leading(SARS-CoV) and SARS-CoV-2.In order to investigate the potential risk of SARS-CoV-2 vertical transmission, we explored ACE2/em> and TMPRSS2, indicating SARS-CoV-2 infection susceptibility.These findings indicate that there may be different SARS-CoV-2 infection susceptibilities of D6 embryos

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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operation of extra-large Fangcang hospitals: experience and lessons from containing the highly contagious SARS-CoV-2-2 Omicron in Shanghai, China

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 165-171 doi: 10.1007/s11684-022-0961-y

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Occurrence and Decay of SARS-CoV-2 in Community Sewage Drainage Systems Article

Qian Dong, Jun-Xiong Cai, Yan-Chen Liu, Hai-Bo Ling, Qi Wang, Luo-Jing Xiang, Shao-Lin Yang, Zheng-Sheng Lu,Yi Liu,Xia Huang, Jiu-Hui Qu

Engineering 2023, Volume 26, Issue 7,   Pages 214-219 doi: 10.1016/j.eng.2022.03.012

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, can be dischargedHowever, a comprehensive understanding of the occurrence, presence, and potential transmission of SARS-CoV-2The results indicated that the risk of long-term emission of SARS-CoV-2 to the environment via vent stacksSARS-CoV-2 were mainly detected in the liquid phase, as opposed to being detected in aerosols, and itsThe surveillance of SARS-CoV-2 in sewage could be a sensitive indicator for the possible presence of

Keywords： SARS-CoV-2     Transmission risk     Drainage system     Sewage     Community    

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Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2-2 Stimulates Neutralizing and Protective Antibody Responses Article

Bo Liu, Ying Yin, Yuxiao Liu, Tiantian Wang, Peng Sun, Yangqin Ou, Xin Gong, Xuchen Hou, Jun Zhang, Hongguang Ren, Shiqiang Luo, Qian Ke, Yongming Yao, Junjie Xu, Jun Wu

Engineering 2022, Volume 13, Issue 6,   Pages 107-115 doi: 10.1016/j.eng.2021.06.012

Abstract:

In 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirusSARS-CoV-2 infects the host by binding to the cellular receptor angiotensin converting enzyme 2 (ACE2To summarize, we have obtained a SARS-CoV-2 vaccine based on the RBD of the S glycoprotein expressed

Keywords： Coronavirus     SARS-CoV-2     Vaccine     Yeast     Receptor-binding domain (RBD)    

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Title Author Date Type Operation

Influenza's Plummeting during the COVID-19 Pandemic: The Roles of Mask-Wearing, Mobility Change, and SARS-CoV-2-2 Interference

Shasha Han, Ting Zhang, Yan Lyu, Shengjie Lai, Peixi Dai, Jiandong Zheng, Weizhong Yang, Xiao-Hua Zhou, Luzhao Feng

Journal Article

ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2: A SYSTEMATIC

Journal Article

Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination

Journal Article

Neutralizing monoclonal antibodies present new prospects to treat SARS-CoV-2 infections

Rongtao Lai, Tianhui Zhou, Xiaogang Xiang, Jie Lu, Haiguang Xin, Qing Xie

Journal Article

SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Journal Article

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Journal Article

Less attention paid to waterborne SARS-CoV-2 spreading in Beijing urban communities

Journal Article

SARS-CoV-2 variants, immune escape, and countermeasures

Journal Article

Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from

Zhengqian Li, Taotao Liu, Ning Yang, Dengyang Han, Xinning Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbing Xiang, Xiangyang Guo

Journal Article

Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection

Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen

Journal Article

Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective

Journal Article

SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article

operation of extra-large Fangcang hospitals: experience and lessons from containing the highly contagious SARS-CoV-2-2 Omicron in Shanghai, China

Journal Article

Occurrence and Decay of SARS-CoV-2 in Community Sewage Drainage Systems

Qian Dong, Jun-Xiong Cai, Yan-Chen Liu, Hai-Bo Ling, Qi Wang, Luo-Jing Xiang, Shao-Lin Yang, Zheng-Sheng Lu,Yi Liu,Xia Huang, Jiu-Hui Qu

Journal Article

Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2-2 Stimulates Neutralizing and Protective Antibody Responses

Bo Liu, Ying Yin, Yuxiao Liu, Tiantian Wang, Peng Sun, Yangqin Ou, Xin Gong, Xuchen Hou, Jun Zhang, Hongguang Ren, Shiqiang Luo, Qian Ke, Yongming Yao, Junjie Xu, Jun Wu

Journal Article