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Review of hand, foot and mouth disease

Lan-Juan LI MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 139-146 doi: 10.1007/s11684-010-0033-6

Abstract: Hand, foot and mouth disease (HFMD) is an acute viral illness that primarily affects infants and young

Keywords: hand     foot and mouth disease     epidemiology     pathogenesis     management     surveillance    

Dynamics of foot-and-mouth disease virus replication in cells at different phases of the cell-division

Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 250-257 doi: 10.15302/J-FASE-2014031

Abstract: Foot-and-mouth-disease virus (FMDV) replicates in epithelial cells.

Keywords: foot-and-mouth disease virus     cell cycle     replication    

Progress on the research and development of human enterovirus 71 (EV71) vaccines

Zhenglun Liang, Qunying Mao, Fan Gao, Junzhi Wang

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 111-121 doi: 10.1007/s11684-012-0237-z

Abstract:

Enterovirus 71 (EV71) infections, which can cause severe complications, have become one of the serious public health issues in the Western Pacific region and China. To date, a number of pharmaceutical companies and institutes have initiated the research and development of EV71 vaccines as a countermeasure. As is the case with innovative vaccine development, there are several critical bottlenecks in EV71 vaccine development that must be overcome before the clinical trials, including the selection of vaccine strain, standardization of the procedure for quantifying neutralizing antibody (NTAb) and antigen, establishment and application of a reference standard and biological standards, development of animal models for the evaluation of protective efficacy, and identification of the target patient population. To tackle these technical obstacles, researchers in Mainland of China have conducted a series of studies concerning the screening of vaccine strains and the establishment of criteria, biological standards and detection methods, thereby advancing EV71 vaccine development. This review summarizes recent worldwide progress on the quality control and evaluation of EV71 vaccines.

Keywords: enterovirus 71 (EV71)     hand     foot     and mouth disease (HFMD)     vaccine    

Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 405-409 doi: 10.1007/s11684-016-0476-5

Abstract:

Periodontitis is the chronic destructive disease of the periodontium (Gums) caused by host bacterial

Keywords: periodontitis     respiratory diseases     acute pneumonia     COPD    

Structural synthesis of ancient Chinese foot-operated silk-reeling mechanism

Kuohung HSIAO, Yuhsun CHEN, Hongsen YAN,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3,   Pages 279-288 doi: 10.1007/s11465-010-0101-2

Abstract: This work synthesizes the structures of the foot-operated silk-reeling mechanism, which was vaguely depicted

Keywords: silk-reeling mechanism     structure of mechanism     reconstruction design     history of machinery    

Planar jumping with stable landing through foot orientation design and ankle joint control

Qilong YUAN, I-Ming CHEN

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 2,   Pages 100-108 doi: 10.1007/s11465-012-0318-3

Abstract: In this work, through determining the upper body posture trajectory in the flight phase, the foot landingTogether with properly designing the trajectory for local center of gravity and the foot landing velocity

Keywords: biped jumping     stable landing control     jumping motion generation    

Initial Experience of NIR-II Fluorescence Imaging-Guided Surgery in Foot and Ankle Surgery

Xiaoxiao Fan,Jie Yang,Huwei Ni,Qiming Xia,Xiaolong Liu,Tianxiang Wu,Lin Li,Paras N. Prasad,Chao Liu,Hui Lin,Jun Qian,

Engineering doi: 10.1016/j.eng.2024.04.011

Abstract: This study aimed to explore the application value of NIR-II fluorescence imaging in foot and ankle surgeriesA lab-established NIR-II fluorescence surgical navigation system was developed and used to navigate footThree types of clinical application scenarios (diabetic foot, calcaneal fracture, and lower extremityUsing the NIR-II fluorescence imaging technique, we observed the ischemic region in the diabetic foot

Keywords: Second near-infrared fluorescence imaging     Foot and ankle surgeries     Indocyanine green     Imaging-guided surgery    

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality

Keywords: chronic obstructive pulmonary disease     heterogeneity     phenotype     genotype     prediction    

et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 354-359 doi: 10.1007/s11684-012-0234-2

Abstract: et’s disease is defined as a multisystemic inflammatory disease.et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population.

Keywords: et’s disease     SNPs     immune gene     genetic study    

Revisiting China’s response to coronavirus disease 2019

Frontiers of Medicine 2023, Volume 17, Issue 6,   Pages 1011-1013 doi: 10.1007/s11684-024-1059-5

Abstract: Revisiting China’s response to coronavirus disease 2019

Acupuncture for the management of dry eye disease

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 975-983 doi: 10.1007/s11684-022-0923-4

Abstract: The effectiveness of using acupuncture for dry eye disease (DED) is controversial.outcomes of interests were (1) to evaluate the efficacy of acupuncture in improving the ocular surface disease

Keywords: dry eye disease     xerophthalmus     acupuncture    

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: the status of major chronic diseases in China, analyzing the key issues and key factors in chronic diseasethe previous projects, this paper proposes the following recommendations as strategies for chronic diseaseWork norms and requirements will then improve the performance and efficiency in chronic disease prevention

Keywords: chronic disease prevention and control     strategy and system construction    

Astrocytes in depression and Alzheimer’s disease

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 829-841 doi: 10.1007/s11684-021-0875-0

Abstract: brain diseases may cause psychosocial and cognitive impairment, such as depression and Alzheimer’s diseasedepression and AD has shown that depression might be a prodrome of progressive degenerative neurological disease

Keywords: astrocytes     depression     Alzheimer’s disease     roles     mechanisms    

Minimal residual disease in solid tumors: an overview

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 649-674 doi: 10.1007/s11684-023-1018-6

Abstract: Minimal residual disease (MRD) is termed as the small numbers of remnant tumor cells in a subset of patients

Keywords: MRD     solid tumor     CTC     ctDNA    

Multislice computed tomography angiography in the diagnosis of cardiovascular disease: 3D visualizations

Zhonghua Sun

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 254-270 doi: 10.1007/s11684-011-0153-7

Abstract: computed tomography (CT) has been widely used in clinical practice for the diagnosis of cardiovascular diseaseangiography has been recognized as the method of choice for detecting and diagnosing head and neck vascular diseaseIn patients with suspected coronary artery disease, although invasive coronary angiography still remainsThe imaging diagnosis of cardiovascular disease is based on a combination of two-dimensional (2D) andan overview of the diagnostic performance of various 2D and 3D CT visualizations in cardiovascular disease

Keywords: cardiovascular disease     multislice computed tomography     three-dimensional reconstruction     diagnosis     visualization    

Title Author Date Type Operation

Review of hand, foot and mouth disease

Lan-Juan LI MD,

Journal Article

Dynamics of foot-and-mouth disease virus replication in cells at different phases of the cell-division

Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN

Journal Article

Progress on the research and development of human enterovirus 71 (EV71) vaccines

Zhenglun Liang, Qunying Mao, Fan Gao, Junzhi Wang

Journal Article

Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Journal Article

Structural synthesis of ancient Chinese foot-operated silk-reeling mechanism

Kuohung HSIAO, Yuhsun CHEN, Hongsen YAN,

Journal Article

Planar jumping with stable landing through foot orientation design and ankle joint control

Qilong YUAN, I-Ming CHEN

Journal Article

Initial Experience of NIR-II Fluorescence Imaging-Guided Surgery in Foot and Ankle Surgery

Xiaoxiao Fan,Jie Yang,Huwei Ni,Qiming Xia,Xiaolong Liu,Tianxiang Wu,Lin Li,Paras N. Prasad,Chao Liu,Hui Lin,Jun Qian,

Journal Article

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Journal Article

et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Journal Article

Revisiting China’s response to coronavirus disease 2019

Journal Article

Acupuncture for the management of dry eye disease

Journal Article

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Journal Article

Astrocytes in depression and Alzheimer’s disease

Journal Article

Minimal residual disease in solid tumors: an overview

Journal Article

Multislice computed tomography angiography in the diagnosis of cardiovascular disease: 3D visualizations

Zhonghua Sun

Journal Article