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2019 novel coronavirus outbreak: a quiz or final exam?

Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 225-228 doi: 10.1007/s11684-020-0753-1

Abstract: The 2019 novel coronavirus (2019-nCoV) is an emerging pathogen and is threatening the global health.

Keywords: 2019-nCoV     novel coronavirus     epidemic     public response    

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 111-119 doi: 10.1007/s11684-016-0446-y

Abstract:

The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memoriesof the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002.

Keywords: coronavirus     MERS     Middle East respiratory syndrome    

Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 120-136 doi: 10.1007/s11684-016-0430-6

Abstract:

The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained

Keywords: MERS     coronavirus     review    

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Frontiers of Medicine doi: 10.1007/s11684-023-1041-7

Abstract: The coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomics

Keywords: SARS-CoV-2     ischemic stroke     stroke     hemorrhagic stroke     cerebral venous thrombosis     vaccination    

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Frontiers of Medicine doi: 10.1007/s11684-023-1011-0

Abstract: ritonavir (Paxlovid) therapy for hemodialysis-dependent patients with severe acute respiratory syndrome coronavirus

Keywords: Paxlovid     hemodialysis     SARS-CoV-2     viral load     chest CT scan    

Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 126-135 doi: 10.1007/s11684-020-0767-8

Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV

Keywords: coronavirus disease 2019     epidemiology     pathology     radiology     clinical characteristics     treatment    

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 126-130 doi: 10.1007/s11684-017-0603-y

Abstract: Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important

Keywords: Middle East respiratory syndrome coronavirus     MERS-CoV     pregnancy     pediatrics    

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords: coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 776-785 doi: 10.1007/s11684-020-0820-7

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus

Keywords: coronavirus disease 2019     pediatrics     emergency     retrospective investigation     severe acute respiratory syndromecoronavirus 2    

Coronavirus Variants—Will New mRNA Vaccines Meet the Challenge?

Jennifer Welsh

Engineering 2021, Volume 7, Issue 6,   Pages 712-714 doi: 10.1016/j.eng.2021.04.005

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein spatial structure

Baicheng HUANG, Kegong TIAN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 218-226 doi: 10.15302/J-FASE-2020324

Abstract:

Emergent coronaviruses (CoVs) such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades. Currently, the emergence of SARS-CoV-2 as a pandemic causes greater public health concern. CoV diversity is due to the large size and replication mechanisms of the genomes together with having bats as their optimum natural hosts. The ecological behavior and unique immune characteristics of bats are optimal for the homologous recombination of CoVs. The relationship of spatial structural characteristics of the spike protein, a protein that is critical for recognition by host receptors, in different CoVs may provide evidence in explaining the coevolution of CoVs and their hosts. This information may help to enhance our understanding of CoV evolution and thus provide part of the basis of preparations for any future outbreaks.

Keywords: bat     coronavirus     evolution     host receptor     spike protein     transmission    

The Scientific Foundation of Chinese Herbal Medicine against COVID-19 Perspective

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Engineering 2020, Volume 6, Issue 10,   Pages 1099-1107 doi: 10.1016/j.eng.2020.08.009

Abstract: text-autospace:none">The recent coronavirus-19 shares a genomic similarity with other coronaviruses, such as severe acute respiratory syndrome coronavirus(SARS-CoV) and Middle East respiratory syndrome  coronavirus (MERS-CoV), and that the pathogenesis

Keywords: Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus     Chinese herbal medicine     Antiviral    

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

Organ function support in patients with coronavirus disease 2019: Tongji experience

Yong Li, Fan He, Ning Zhou, Jia Wei, Zeyang Ding, Luyun Wang, Peng Chen, Shuiming Guo, Binhao Zhang, Xiaoning Wan, Wei Zhu, on behalf of Multidisciplinary Team for COVID-19, Optical Valley Branch of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 232-248 doi: 10.1007/s11684-020-0774-9

Abstract: Coronavirus disease 2019 (COVID-19) is a highly contagious disease and a serious threat to human health

Keywords: COVID-19     severe and critical type     organ function support    

Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 752-759 doi: 10.1007/s11684-020-0813-6

Abstract: study aimed to evaluate the efficacy of Chinese herbal medicine (CHM) in patients with severe/critical coronavirus

Keywords: COVID-19     CHM     mortality     a retrospective cohort study    

Title Author Date Type Operation

2019 novel coronavirus outbreak: a quiz or final exam?

Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao

Journal Article

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Journal Article

Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Journal Article

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Journal Article

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Journal Article

Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Journal Article

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Journal Article

Coronavirus Variants—Will New mRNA Vaccines Meet the Challenge?

Jennifer Welsh

Journal Article

Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein spatial structure

Baicheng HUANG, Kegong TIAN

Journal Article

The Scientific Foundation of Chinese Herbal Medicine against COVID-19

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Journal Article

Organ function support in patients with coronavirus disease 2019: Tongji experience

Yong Li, Fan He, Ning Zhou, Jia Wei, Zeyang Ding, Luyun Wang, Peng Chen, Shuiming Guo, Binhao Zhang, Xiaoning Wan, Wei Zhu, on behalf of Multidisciplinary Team for COVID-19, Optical Valley Branch of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China

Journal Article

Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Journal Article