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Revealing High-Efficiency Natural Mycotoxin Antidotes in Zebrafish Model Screening Against Zearalenone-Induced Toxicity

Hong-Yun Zhang,Wei-Dan Jiang,Pei Wu,Yang Liu,Hong-Mei Ren,Xiao-Wan Jin,Xiao-Qiu Zhou,Lin Feng,

Engineering doi: 10.1016/j.eng.2024.03.016

Abstract: initially identified 96 NPs and evaluated the potency and efficacy of two effective candidate compounds, fraxetinNotably, throughout the process, fraxetin consistently stood out as the most promising NP.Biological pathway analysis and functional verification revealed that fraxetin completely reversed the

Keywords： Zearalenone     Natural products     Phenotype-based screening     Transcriptome analysis     Fraxetin    

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Revealing High-Efficiency Natural Mycotoxin Antidotes in Zebrafish Model Screening Against Zearalenone-Induced Toxicity

Hong-Yun Zhang,Wei-Dan Jiang,Pei Wu,Yang Liu,Hong-Mei Ren,Xiao-Wan Jin,Xiao-Qiu Zhou,Lin Feng,

Journal Article