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The imperative need to develop guidelines to manage human versus machine intelligence

Donald KENNEDY, Simon P. PHILBIN

Frontiers of Engineering Management 2018, Volume 5, Issue 2,   Pages 182-194 doi: 10.15302/J-FEM-2018085

Abstract: Machine intelligence is increasingly entering roles that were until recently dominated by human intelligence. As humans now depend upon machines to perform various tasks and operations, there appears to be a risk that humans are losing the necessary skills associated with producing competitively advantageous decisions. Therefore, this research explores the emerging area of human versus machine decision-making. An illustrative engineering case involving a joint machine and human decision-making system is presented to demonstrate how the outcome was not satisfactorily managed for all the parties involved. This is accompanied by a novel framework and research agenda to highlight areas of concern for engineering managers. We offer that the speed at which new human-machine interactions are being encountered by engineering managers suggests that an urgent need exists to develop a robust body of knowledge to provide sound guidance to situations where human and machine decisions conflict. Human-machine systems are becoming pervasive yet this research has revealed that current technological approaches are not adequate. The engineering insights and multi-criteria decision-making tool from this research significantly advance our understanding of this important area.

Keywords： human intelligence & machine intelligence     HI-MI     decision-making     artificial intelligence    

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Association of metabolic syndrome with arterial compliance in children and adolescents

ZHANG Li, MI Jie, LI Ming, JIANG Benyu

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 68-73 doi: 10.1007/s11684-007-0014-6

Abstract: The association of metabolic syndrome (MS) with arterial compliance in children and adolescents was explored. 337 subjects (188 men and 149 women) aged 6 18 (10.95?3.01) years, out of Beijing Child Metabolic Syndrome Study , were divided into three case groups (one component, two components, three & more components of MS) and one control group based on the Cook s MS definition in children and adolescents. Measurements including anthropometry, blood pressure, fasting plasma glucose and insulin, serum lipid profile were done. Homeostasis model assessment for insulin resistance (HOMA-IR) index was calculated for estimating individual insulin resistance. Arterial compliance was measured using digital pulse wave analyzing method from the pulse trace machine (Micro medical, London), and then the stiffness index (SI) was determined. The mean value of SI in MS group was significant higher than that in control group [(7.69?1.63) vs (6.25?0.86) m/s, <0.01]. With the increase of the clustering of MS components, SI and HOMA-IR were gradually increased. After taking account of gender, age and pubertal development, the partial correlation analysis showed that the amount of components of MS and HOMA-IR were positively correlated with SI (both values were less than 0.05). The arterial compliance of MS group was significantly lowered in children and adolescents, and with the increase of the clustering of MS components, arterial compliance was gradually decreased. It was suggested that arterial compliance assessment in children and adolescents was important for early prevention of cardiovascular diseases.

Keywords： compliance assessment     correlation analysis     cardiovascular     clustering     HOMA-IR    

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Catalytic cracking of endothermic fuels in coated tube reactor

LI Jia, ZOU Jijun, ZHANG Xiangwen, GUO Wei, MI Zhentao

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 2,   Pages 181-185 doi: 10.1007/s11705-008-0032-1

Abstract: Suspensoid of HZSM-5 or HY zeolites mixed with a self-made ceramic-like binder was coated on the inner wall of a tubular reactor by gas-aided fluid displacement technology. The coated zeolites were characterized by means of X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The coating thickness is 10–20 ?m and the particle size of the zeolites is in the range of 1–5 ?m. In the coated reactor, cracking of endothermic fuels including -dodecane and aviation fuel RP-3 was carried out separately under supercritical conditions at 600°C and 625°C to investigate their heat sinks and conversion of catalytic reactions. For the reaction catalyzed by HY(25% mass fraction) coating, the heat sink capacity of -dodecane are 815.7 and 901.9 kJ/kg higher than that of the bare tube at 600°C and at 625°C, respectively. Conversion of -dodecane also increases from 42% to 60% at 600°C and from 66% to 80% at 625°C. The coated zeolite can significantly inhibit the carbon deposition during supercritical cracking reactions.

Keywords： HZSM-5     self-made ceramic-like     gas-aided     Conversion     Suspensoid    

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Pilot scale autothermal gasification of coconut shell with CO

Bayu PRABOWO,Herri SUSANTO,Kentaro UMEKI,Mi YAN,Kunio YOSHIKAWA

Frontiers in Energy 2015, Volume 9, Issue 3,   Pages 362-370 doi: 10.1007/s11708-015-0375-5

Abstract: This paper explored the feasibility and benefit of CO utilization as gasifying agent in the autothermal gasification process. The effects of CO injection on reaction temperature and producer gas composition were examined in a pilot scale downdraft gasifier by varying the CO /C ratio from 0.6 to 1.6. O was injected at an equivalence ratio of approximately 0.33–0.38 for supplying heat through partial combustion. The results were also compared with those of air gasification. In general, the increase in CO injection resulted in the shift of combustion zone to the downstream of the gasifier. However, compared with that of air gasification, the long and distributed high temperature zones were obtained in CO -O gasification with a CO /C ratio of 0.6–1.2. The progress of the expected CO to CO conversion can be implied from the relatively insignificant decrease in CO fraction as the CO /C ratio increased. The producer gas heating value of CO -O gasification was consistently higher than that of air gasification. These results show the potential of CO -O gasification for producing high quality producer gas in an efficient manner, and the necessity for more work to deeply imply the observation.

Keywords： biomass gasification     CO2     downdraft gasifier     autothermal    

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Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural network model

Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 112-120 doi: 10.1007/s11684-017-0582-z

Abstract: Comprehension of the medical diagnoses of doctors and treatment of diseases is important to understand the underlying principle in selecting appropriate acupoints. The pattern recognition process that pertains to symptoms and diseases and informs acupuncture treatment in a clinical setting was explored. A total of 232 clinical records were collected using a Charting Language program. The relationship between symptom information and selected acupoints was trained using an artificial neural network (ANN). A total of 11 hidden nodes with the highest average precision score were selected through a tenfold cross-validation. Our ANN model could predict the selected acupoints based on symptom and disease information with an average precision score of 0.865 (precision, 0.911; recall, 0.811). This model is a useful tool for diagnostic classification or pattern recognition and for the prediction and modeling of acupuncture treatment based on clinical data obtained in a real-world setting. The relationship between symptoms and selected acupoints could be systematically characterized through knowledge discovery processes, such as pattern identification.

Keywords： acupuncture     indication     neural network     pattern identification     prediction    

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Histone variants: critical determinants in tumour heterogeneity

Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Jin Wang, Jianqing Mi, Sophie Rousseaux, Saadi Khochbin

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 289-297 doi: 10.1007/s11684-018-0667-3

Abstract: Malignant cell transformation could be considered as a series of cell reprogramming events driven by oncogenic transcription factors and upstream signalling pathways. Chromatin plasticity and dynamics are critical determinants in the control of cell reprograming. An increase in chromatin dynamics could therefore constitute an essential step in driving oncogenesis and in generating tumour cell heterogeneity, which is indispensable for the selection of aggressive properties, including the ability of cells to disseminate and acquire resistance to treatments. Histone supply and dosage, as well as histone variants, are the best-known regulators of chromatin dynamics. By facilitating cell reprogramming, histone under-dosage and histone variants should also be crucial in cell transformation and tumour metastasis. Here we summarize and discuss our knowledge of the role of histone supply and histone variants in chromatin dynamics and their ability to enhance oncogenic cell reprogramming and tumour heterogeneity.

Keywords： cancer-testis     TH2B     TH2A     H1T     H1.0     H1F0     linker histones    

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Protein security and food security in China

Zheng RUAN,Shumei MI,Yan ZHOU,Zeyuan DENG,Xiangfeng KONG,Tiejun LI,Yulong YIN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 2,   Pages 144-151 doi: 10.15302/J-FASE-2015062

Abstract: Food security, the need to meet nutritional requirements, and four main problems for food protein security in China are analyzed. From the perspective of residents’ nutritional requirements and balanced dietary patterns, the conclusion is that food security in China is in essence dependent on protein production and security of supply and that fat and carbohydrates supply in China can reach self-sufficiency. Considering the situation of food protein production and consumption in China, policy suggestions are made, which could ensure a balanced supply and demand for food protein and food security in China.

Keywords： food security     protein security     nutrition     dietary pattern    

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Formation of coke in thermal cracking of jet fuel under supercritical conditions

ZHU Yuhong, YU Caixiang, LI Zimu, MI Zhentao, ZHANG Xiangwen

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 17-21 doi: 10.1007/s11705-008-0024-1

Abstract: Continuous-flow reactor experiments were carried out to study coke formation from thermal cracking of home-made jet fuel RP-3 under supercritical conditions. The mechanism and precursor of coke forming were analyzed. The starting cracking temperature of RP-3 fuel was determined to be 471.8°C by differential scanning calorimetry (DSC). Temperature-programmed oxidation and scanning electron microscopy (SEM) characterizations of the stressed tubes showed that there are three different coke species including chemisorbed carbon, amorphous carbon and filamentous coke in the solid deposits. More than 90% of coke deposits are carried away by the supercritical fluid, which has strong capabilities of extraction for coke deposits and their precursors. There were 17.1 wt-% of iron and 11.1 wt-% of chromium found on the coke surface detected by energy dispersive spectroscopy (EDS) which suggests carburetion on alloy. RP-3 fuel and its cracking liquids were analyzed by GC-MS,which showed that the content of alkyl benzene and alkyl naphthalene increased evidently in cracking liquids.

Keywords： dispersive spectroscopy     different     extraction     calorimetry     filamentous    

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Regeneration of Fe

Ruizhuang ZHAO, Ju SHANGGUAN, Yanru LOU, Jin SONG, Jie MI, Huiling FAN

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 423-428 doi: 10.1007/s11705-010-0503-z

Abstract: Regeneration of a high-temperature coal gas desulfurization sorbent is a key technology in its industrial applications. A Fe O -based high-temperature coal gas desulfurizer was prepared using red mud from steel factory. The influences of regeneration temperature, space velocity and regeneration gas concentration in SO atmosphere on regeneration performances of the desulfurization sorbent were tested in a fixed bed reactor. The changes of phase and the composition of the Fe O -based high-temperature coal gas desulfurization sorbent before and after regeneration were examined by X-ray diffraction(XRD) and X-ray Photoelectron spectroscopy(XPS), and the changes of pore structure were characterized by the mercury intrusion method. The results show that the major products are Fe O and elemental sulfur; the influences of regeneration temperature, space velocity and SO concentration in inlet on regeneration performances and the changes of pore structure of the desulfurization sorbent before and after regeneration are visible. The desulfurization sorbent cannot be regenerated at 500°C in SO atmosphere. Within the range of 600°C – 800°C, the time of regeneration becomes shorter, and the regeneration conversion increases as the temperature rises. The time of regeneration also becomes shorter, and the elemental sulfur content of tail gas increases as the SO concentration in inlet is increased. The increase in space velocity enhances the reactive course; the best VSP is 6000 h for regeneration conversion. At 800°C, 20 vol-% SO and 6000 h , the regeneration conversion can reach nearly to 90%.

Keywords： high-temperature coal gas     Fe2O3 desulfurization sorbent     SO2 atmosphere     regeneration behaviors     sulfur recovery    

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Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 341-347 doi: 10.1007/s11684-011-0169-z

Abstract: Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML). The prognosis of APL has changed from the worst among the AMLs to currently the best. The application of all- retinoic acid (ATRA) in the induction therapy of APL decreases the high mortality of newly diagnosed patients, thereby significantly improving the response rate. ATRA combined with anthracycline-based chemotherapy is the current standard treatment, and for high-risk patients, high doses cytarabine have a beneficial effect on relapse prevention. In recent years, the indications of arsenic trioxide (ATO) therapy for APL have been extended from the salvage therapy for relapse patients to the first-line treatment of APL. The introduction of both ATRA and ATO represents great achievements in translational medicine. In this review article, we discuss the therapeutic strategies for this disease, including the initial approaches to newly diagnosed patients, prevention, and treatment of side effects and relapse to ensure the best and timely treatment for each newly diagnosed APL patient.

Keywords： acute promyelocytic leukemia     all-trans retinoic acid     arsenic trioxide    

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Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 1,   Pages 107-119 doi: 10.1007/s11465-018-0496-8

Abstract:

Tissue engineering (TE) is an integrated discipline that involves engineering and natural science in the development of biological materials to replace, repair, and improve the function of diseased or missing tissues. Traditional medical and surgical treatments have been reported to have side effects on patients caused by organ necrosis and tissue loss. However, engineered tissues and organs provide a new way to cure specific diseases. Scaffold fabrication is an important step in the TE process. This paper summarizes and reviews the widely used scaffold fabrication methods, including conventional methods, electrospinning, three-dimensional printing, and a combination of molding techniques. Furthermore, the differences among the properties of tissues, such as pore size and distribution, porosity, structure, and mechanical properties, are elucidated and critically reviewed. Some studies that combine two or more methods are also reviewed. Finally, this paper provides some guidance and suggestions for the future of scaffold fabrication.

Keywords： tissue engineering     scaffolds     electrospinning     3D printing     molding techniques     conventional methods    

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Geoengineering and the blockchain: Coordinating Carbon Dioxide Removal and Solar Radiation Management to tackle future emissions

Andrew LOCKLEY, Zhifu MI, D’Maris COFFMAN

Frontiers of Engineering Management 2019, Volume 6, Issue 1,   Pages 38-51 doi: 10.1007/s42524-019-0010-y

Abstract:

Geoengineering is a proposed response to anthropogenic global warming (AGW). Conventionally it consists of two strands: Solar Radiation Management (SRM), which is fast-acting, incomplete but inexpensive, and Carbon Dioxide Removal (CDR), which is slower acting, more expensive, and comprehensive. Pairing SRM and CDR offers a contractually complete solution for future emissions if effectively-scaled and coordinated. SRM offsets warming, while CDR takes effect. We suggest coordination using a blockchain, i.e. smart contracts and a distributed ledger. Specifically, we integrate CDR futures with time and volume-matched SRM orders, to address emissions contractually before release. This provides an economically and environmentally proportionate solution to CO2 emissions at the wellhead, with robust contractual transparency, and minimal overhead cost.

Keywords： Geoengineering     Solar Radiation Management     Carbon Dioxide Removal     futures markets     smart contracts     blockchain    

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Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions

Zhiruo Zhang, Shelan Liu, Mi Xiang, Shijian Li, Dahai Zhao, Chaolin Huang, Saijuan Chen

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 229-231 doi: 10.1007/s11684-020-0765-x

Abstract: The outbreak of a novel coronavirus disease (COVID-19, caused by the 2019-nCoV infection) in December 2019 is one of the most severe public health emergencies since the founding of People’s Republic of China in 1949. Healthcare personnel (HCP) nationwide are facing heavy workloads and high risk of infection, especially those who care for patients at the epicenter of the outbreak, Hubei Province. Sadly, as of February 20, 2020, over two thousand COVID-19 cases are confirmed among HCP from 476 hospitals nationwide, with nearly 90% of them from Hubei Province. Based on literature search and interviews with some HCP working at Wuhan, capital city of Hubei, we have summarized some of the effective measures taken to reduce infection among HCP, and also made suggestions for improving occupational safety during an infectious disease outbreak. The experience and lessons learned should be a valuable asset for international health community to contain the ongoing COVID-19 epidemic around the world.

Keywords： healthcare personnel     COVID-19     infectious diseases    

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A red water occurrence in drinking water distribution systems caused by changes in water source in Beijing, China: mechanism analysis and control measures

ZHANG Xiaojian,MI Zilong,WANG Yang,LIU Shuming,NIU Zhangbin,LU Pinpin,WANG Jun,GU Junnong,CHEN Chao

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 3,   Pages 417-426 doi: 10.1007/s11783-013-0558-4

Abstract: A red water phenomenon occurred in several communities few days after the change of water source in Beijing, China in 2008. In this study, the origin of this problem, the mechanism of iron release and various control measures were investigated. The results indicated that a significant increase in sulphate concentration as a result of the new water source was the cause of the red water phenomenon. The mechanism of iron release was found that the high-concentration sulphate in the new water source disrupted the stable shell of scale on the inner pipe and led to the release of iron compounds. Experiments showed that the iron release rate in the new source water within pipe section was over 11-fold higher than that occurring within the local source water. The recovery of tap water quality lasted several months despite ameliorative measures being implemented, including adding phosphate, reducing the overall proportion of the new water source, elevating the pH and alkalinity, and utilizing free chlorine as a disinfectant instead of chloramine. Adding phosphate was more effective and more practical than the other measures. The iron release rate was decreased after the addition of 1.5 mg·L orthophosphate- P, tripolyphosphate-P and hexametaphosphate-P by 68%, 83% and 87%, respectively. Elevating the pH and alkalinity also reduced the iron release rate by 50%. However, the iron release rate did not decreased after replacing chloramine by 0.5–0.8 mg·L of free chlorine as disinfectant.

Keywords： iron release     drinking water distribution system     sulphate     phosphate     red water control     water quality stability    

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PWR-FBR with closed fuel cycle for a sustainable nuclear energy supply in China

XU Mi

Frontiers in Energy 2007, Volume 1, Issue 2,   Pages 129-134 doi: 10.1007/s11708-007-0016-8

Abstract: From the thermal reactor to the fast reactor and then to the fusion reactor; this is the three-step strategy that has been decided for a sustainable nuclear energy supply in China. As the main thermal reactor type, the commercialized development phase of the pressurized water reactor (PWR) has been stepped up. The development of the fast reactor (FBR) is still in the early stage, marked by China experimental fast reactor (CEFR), which is currently under construction. According to the strategy study on the fast reactor development in China, its engineering development will be divided into three steps: the CEFR with a power of 65 MWt/20 MWe; the China prototype fast reactor (CPFR) with a power of 1 500 MWt/600 MWe; and the China demonstration fast reactor (CDFR) with a power of 2 500 3 750 MWt/1 000 1 500 MWe. With regards to the fuel cycle, a 100 t/a PWR spent fuel reprocessing pilot plant and a 500 kg/ a MOX fabrication plant are under construction. A project involving the construction of an industrial reprocessing plant and an MOX fabrication plant are also under application phase.

Keywords： reactor development     reprocessing     MWt/600     demonstration     three-step strategy    

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Title Author Date Type Operation

The imperative need to develop guidelines to manage human versus machine intelligence

Donald KENNEDY, Simon P. PHILBIN

Journal Article

Association of metabolic syndrome with arterial compliance in children and adolescents

ZHANG Li, MI Jie, LI Ming, JIANG Benyu

Journal Article

Catalytic cracking of endothermic fuels in coated tube reactor

LI Jia, ZOU Jijun, ZHANG Xiangwen, GUO Wei, MI Zhentao

Journal Article

Pilot scale autothermal gasification of coconut shell with CO

Bayu PRABOWO,Herri SUSANTO,Kentaro UMEKI,Mi YAN,Kunio YOSHIKAWA

Journal Article

Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural network model

Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung

Journal Article

Histone variants: critical determinants in tumour heterogeneity

Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Jin Wang, Jianqing Mi, Sophie Rousseaux, Saadi Khochbin

Journal Article

Protein security and food security in China

Zheng RUAN,Shumei MI,Yan ZHOU,Zeyuan DENG,Xiangfeng KONG,Tiejun LI,Yulong YIN

Journal Article

Formation of coke in thermal cracking of jet fuel under supercritical conditions

ZHU Yuhong, YU Caixiang, LI Zimu, MI Zhentao, ZHANG Xiangwen

Journal Article

Regeneration of Fe

Ruizhuang ZHAO, Ju SHANGGUAN, Yanru LOU, Jin SONG, Jie MI, Huiling FAN

Journal Article

Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Journal Article

Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Journal Article

Geoengineering and the blockchain: Coordinating Carbon Dioxide Removal and Solar Radiation Management to tackle future emissions

Andrew LOCKLEY, Zhifu MI, D’Maris COFFMAN

Journal Article

Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions

Zhiruo Zhang, Shelan Liu, Mi Xiang, Shijian Li, Dahai Zhao, Chaolin Huang, Saijuan Chen

Journal Article

A red water occurrence in drinking water distribution systems caused by changes in water source in Beijing, China: mechanism analysis and control measures

ZHANG Xiaojian,MI Zilong,WANG Yang,LIU Shuming,NIU Zhangbin,LU Pinpin,WANG Jun,GU Junnong,CHEN Chao

Journal Article

PWR-FBR with closed fuel cycle for a sustainable nuclear energy supply in China

XU Mi

Journal Article