Resource Type

Journal Article 273

Conference Topics 1

Conference Videos 1

Year

2024 2

2023 28

2022 21

2021 36

2020 19

2019 16

2018 21

2017 21

2016 17

2015 18

2014 14

2013 11

2012 12

2011 6

2010 8

2009 8

2008 1

2007 4

2006 1

2004 1

open ︾

Keywords

Immunoglobulin G 6

Glycosylation 4

N2O 4

n-heptane 4

CH4 3

CO2 3

COVID-19 3

Denitrification 3

N 2

N-nitrosodimethylamine 2

N-nitrosodimethylamine (NDMA) 2

C/N ratio 2

COD/N ratio 2

Capillary gel electrophoresis 2

Colorectal cancer 2

Greenhouse gas 2

H7N9 2

N 2

N235 2

open ︾

Search scope:

排序： Display mode:

IgG N-Glycosylation Cardiovascular Age Tracks Cardiovascular Risk Beyond Calendar Age Article

Zhiyuan Wu, Zheng Guo, Yulu Zheng, Yutao Wang, Haiping Zhang, Huiying Pan, Zhiwei Li, Lois Balmer, Xia Li, Lixin Tao, Xiuhua Guo, Wei Wang

Engineering 2023, Volume 26, Issue 7,   Pages 99-107 doi: 10.1016/j.eng.2022.12.004

Abstract: However, the usable capacity of IgG N-glycosylation profiles for the risk stratification of cardiovascularmachine learning (recursive feature elimination and penalized regression algorithms) and developed an IgG N-glycosylationThe strongest contributors to GlyCage index were fucosylated N-glycans with bisecting NN-glycosylationbetween GlyCage and calendar age independently indicates the cardiovascular risk, suggesting that IgG N-glycosylation

Keywords： IgG N-glycosylation cardiovascular age     Cardiovascular aging     Immunoglobulin G     Glycosylation     Inflammation    

HTML PDF Collect

Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian Randomization Article

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Engineering 2023, Volume 26, Issue 7,   Pages 74-88 doi: 10.1016/j.eng.2022.11.004

Abstract:

Bidirectional causalityAlthough the association between immunoglobulin G (IgG) N-glycosylation and, in the reverse MR analysis of the integrated metabolic-QTL variants with the GWAS results for IgG N-glycosylationfor GP9 (HDL-C)) genetically determined metabolic traits were found to be related to the risk of IgG N-glycosylationcomprehensively bidirectional MR analyses provide suggestive evidence of bidirectional causality between IgG N-glycosylationand metabolic traits, possibly revealing a new richness in the biological mechanism between IgG N-glycosylation

Keywords： Mendelian randomization study     Immunoglobulin G     N-glycosylation     Metabolic traits     Quantitative trait    

HTML PDF Collect

Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle Article

Julija Jurić, Hongli Peng, Manshu Song, Frano Vučković, Jelena Šimunović, Irena Trbojević-Akmačić, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc

Engineering 2023, Volume 26, Issue 7,   Pages 108-118 doi: 10.1016/j.eng.2022.10.020

Abstract: The modification of IgG N-glycosylation is considered to be one of the various mechanisms by which sexcycle is the central sex hormone-related physiological process in most women of reproductive age, IgG N-glycosylationWe observed cyclic periodic changes in the N-glycosylation of IgG in association with the menstrual cycleOn the integrated cohort level, the modeled average menstrual cycle effect on the abundance of IgG N-glycosylationvariation in the abundance of digalactosylation could be attributed to interpersonal differences in IgG N-glycosylation

Keywords： N-glycosylation     Immunoglobulin G     Menstrual cycle     Female sex hormones     Estrogen     Progesterone     Testosterone    

HTML PDF Collect

Twelve Years of Genome-Wide Association Studies of Human Protein N-Glycosylation Review

Anna Timoshchuk, Sodbo Sharapov, Yurii S. Aulchenko

Engineering 2023, Volume 26, Issue 7,   Pages 17-31 doi: 10.1016/j.eng.2023.03.013

Abstract: In Section 1, we provide a brief overview of the N-glycan's structural organization, andNext, in Section 3, we summarize, systemize, and generalize the results from current N-glycosylationUntil now, such studies have been limited to an analysis of the human blood plasma N-glycomeand the N-glycosylation of immunoglobulin G and transferrin.mechanisms of action and biological targets of genetic variation that have been implicated in human protein N-glycosylation

Keywords： Glycome     Glycans     N-glycosylation     Genomics     Genetics     GWAS    

HTML PDF Collect

Transcription Factors HNF1A, HNF4A, and FOXA2 Regulate Hepatic Cell Protein N-Glycosylation Article

Vedrana Vičić Bočkor,Nika Foglar,Goran Josipović,Marija Klasić,Ana Vujić,Branimir Plavša,Toma Keser,Samira Smajlović,Aleksandar Vojta,Vlatka Zoldoš

Engineering 2024, Volume 32, Issue 1,   Pages 58-69 doi: 10.1016/j.eng.2023.09.019

Abstract: The effect is better seen as an overall change in the total HepG2 N-glycome, primarily due toWe propose an alternative way to evaluate the N-glycome composition via estimating the overallthe mutual activation of HNF1A–FOXA2 and HNF4A–FOXA2 affecting glyco-genes and protein glycosylation

Keywords： factor 1 alpha (HNF1A)     Hepatocyte nuclear factor 4 alpha (HNF4A)     Forkhead box protein A2 (FOXA2)     N-glycosylation    

HTML PDF Collect

Novel Insight into the Etiology of Haff Disease by Mapping the N-Glycome with Orthogonal Mass Article

Si Liu, Yuanyuan Liu, Jiajing Lin, Bi-Feng Liu, Zhenyu He, Xiaomin Wu, Xin Liu

Engineering 2023, Volume 26, Issue 7,   Pages 63-73 doi: 10.1016/j.eng.2022.09.012

Abstract: Profiling of the N-glycome in HD would assist in deciphering the underlying molecular mechanismof the disease, whereas HD-associated glycosylation has never been explored.N-glycome profiles of both serum and serum-derived immunoglobulin G (IgG) in HD were characterizedOur study reveals the association of differential IgG N-glycosylation with HD, providing new insight

Keywords： Haff disease     Serum     Immunoglobulin G     Glycosylation     Disease pathogenesis    

HTML PDF Collect

Catalysis and deactivation of montmorillonite K10 in the aryl O -glycosylation of glycosyl trichloroacetoimidates

Xiaoliu LI, Xinhao YAN, Zhiwei LI, Hua CHEN, Pingzhu ZHANG,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 3,   Pages 342-347 doi: 10.1007/s11705-009-0279-1

Abstract: The catalysis of montmorillonite K10 (MK10) for aryl -glycosylation of glycosyl trichloroacetimidatesIt was found that the catalyst MK10 is deactivated gradually in the recycle glycosylation.X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Thermogravimetric analysis (TGA), and N

Keywords： photoelectron spectroscopy     adsorption-desorption     glycosylation     deactivated     diffraction    

HTML PDF Collect

Human Prostate-Specific Antigen Carries N-Glycans with Ketodeoxynononic Acid Article

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Engineering 2023, Volume 26, Issue 7,   Pages 119-131 doi: 10.1016/j.eng.2023.02.009

Abstract: Here, we report for the first time that Kdn is expressed on prostate-specific antigen (PSA) Nglycosylation feature was also identified in a urinary PSA cohort in relation to prostate

Keywords： Ketodeoxynononic acid     Kdn     Glycosylation     Prostate cancer     Prostate-specific antigen    

HTML PDF Collect

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract:

Podoplanin (PDPN) is a mucin-type O-glycoprotein expressed in diverse cell types, such as lymphatic endothelial cells (LECs) in the vascular system and fibroblastic reticular cells (FRCs) in lymph nodes. PDPN on LECs or FRCs activates CLEC-2 in platelets, triggering platelet activation and/or aggregation through downstream signaling events, including activation of Syk kinase. This mechanism is required to initiate and maintain separation of blood and lymphatic vessels and to stabilize high endothelial venule integrity within lymph nodes. In the vascular system, normal expression of PDPN at the LEC surface requires transcriptional activation of Pdpn by Prox1 and modification of PDPN with core 1-derived O-glycans. This review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid organ maintenance and discusses the mechanisms that regulate PDPN expression related to its function.

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid    

HTML PDF Collect

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications Article

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Engineering 2021, Volume 7, Issue 10,   Pages 1441-1451 doi: 10.1016/j.eng.2020.07.014

Abstract: 21 possible glycosites in the HCoV-19 spike protein (S protein), 20 are completely occupied by Nglycosylation sites in human angiotensin I converting enzyme 2 (hACE2) were found to be completelyoccupied, mainly by complex N-glycans.However, glycosylation did not directly contribute to the binding affinity between HCoV-19 S proteinRefined structural models of HCoV-19 S protein and hACE2 were built by adding N-glycan and PTMs

Keywords： N-glycosylation     COVID-19     Spike protein     hACE2     Structure    

HTML PDF Collect

High-Throughput Profiling of Serological Immunoglobulin G N-Glycome as a Noninvasive Biomarker Article

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Engineering 2023, Volume 26, Issue 7,   Pages 44-53 doi: 10.1016/j.eng.2023.02.008

Abstract:

Immunoglobulin G (IgG) N-glycosylation plays a crucial role in the developmentCanonical correlation analysis (CCA) was used to explore the correlation between IgG N-glycosylationIn addition, the composition of IgG N-glycans was correlated with that of inflammatory cytokinesOur findings demonstrate that IgG N-glycosylation plays an important role in modulating the pathogenesisSerological IgG N-glycosylation is thus a potential candidate for noninvasively assisting in the clinical

Keywords： Gastrointestinal cancer     Glycosylation     Immunoglobulin G     Diagnostic biomarker    

HTML PDF Collect

Effect of Cu-ZSM-5 catalysts with different CuO particle size on selective catalytic oxidation of N,N-Dimethylformamide

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 10, doi: 10.1007/s11783-022-1557-0

Abstract:

● A series of Cu-ZSM-5 catalysts were tested for DMF selective catalytic oxidation.

Keywords： N     N-Dimethylformamide     Selective catalytic oxidation     Cu-ZSM-5     CuO particle size    

HTML PDF Collect

Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:1 to 14:1) for simultaneous C & N removal

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1522-y

Abstract:

• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.

Keywords： Methanogens     Biological Nitrogen Removal (BNR)     Simultaneous     Methammox     C:N ratio    

HTML PDF Collect

Effect of fly ash and slag on concrete: Properties and emission analyses

TAM, Khoa N. LE, Ana Catarina Jorge EVANGELISTA, Anthony BUTERA, Cuong N. N. TRAN, Ashraf TEARA

Frontiers of Engineering Management 2019, Volume 6, Issue 3,   Pages 395-405 doi: 10.1007/s42524-019-0019-2

Abstract: Recycled concrete is a material with the potential to create a sustainable construction industry. However, recycled concrete presents heterogeneous properties, thereby reducing its applications for some structural purposes and enhancing its application in pavements. This paper provides an insight into a solution in the deformation control for recycled concrete by adding supplementary cementitious materials fly ash and blast furnace slag. Results of this study indicated that the 50% fly ash replacement of Portland cement increased the rupture modulus of the recycled concrete. Conversely, a mixture with over 50% cement replacement by either fly ash or slag or a combination of both exhibited detrimental effect on the compressive strength, rupture modulus, and drying shrinkage. The combined analysis of environmental impacts and mechanical properties of recycled concrete demonstrated the possibility of optimizing the selection of recycled concrete because the best scenario in this study was obtained with the concrete mixture M8 (50% of fly ash+ 100% recycled coarse aggregate).

Keywords： recycled aggregate     recycled concrete     fly ash and slag    

HTML PDF Collect

Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 11-24 doi: 10.15302/J-FASE-2016092

Abstract: The H9N2 and H5N1 avian influenza viruses (AIVs) have been circulating in poultry in China and becomeinfluenza viruses, such as the well-known viruses of the highly pathogenic avian influenza (HPAI) H5N2and the 2013 novel H7N7, H7N9 and H10N8 subtypes, thereby threatening both the poultry industry and

Keywords： avian influenza virus     H9N2     H5N1     novel viruses     public health    

HTML PDF Collect

Title Author Date Type Operation

IgG N-Glycosylation Cardiovascular Age Tracks Cardiovascular Risk Beyond Calendar Age

Zhiyuan Wu, Zheng Guo, Yulu Zheng, Yutao Wang, Haiping Zhang, Huiying Pan, Zhiwei Li, Lois Balmer, Xia Li, Lixin Tao, Xiuhua Guo, Wei Wang

Journal Article

Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian Randomization

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Journal Article

Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle

Julija Jurić, Hongli Peng, Manshu Song, Frano Vučković, Jelena Šimunović, Irena Trbojević-Akmačić, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc

Journal Article

Twelve Years of Genome-Wide Association Studies of Human Protein N-Glycosylation

Anna Timoshchuk, Sodbo Sharapov, Yurii S. Aulchenko

Journal Article

Transcription Factors HNF1A, HNF4A, and FOXA2 Regulate Hepatic Cell Protein N-Glycosylation

Vedrana Vičić Bočkor,Nika Foglar,Goran Josipović,Marija Klasić,Ana Vujić,Branimir Plavša,Toma Keser,Samira Smajlović,Aleksandar Vojta,Vlatka Zoldoš

Journal Article

Novel Insight into the Etiology of Haff Disease by Mapping the N-Glycome with Orthogonal Mass

Si Liu, Yuanyuan Liu, Jiajing Lin, Bi-Feng Liu, Zhenyu He, Xiaomin Wu, Xin Liu

Journal Article

Catalysis and deactivation of montmorillonite K10 in the aryl O -glycosylation of glycosyl trichloroacetoimidates

Xiaoliu LI, Xinhao YAN, Zhiwei LI, Hua CHEN, Pingzhu ZHANG,

Journal Article

Human Prostate-Specific Antigen Carries N-Glycans with Ketodeoxynononic Acid

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Journal Article

High-Throughput Profiling of Serological Immunoglobulin G N-Glycome as a Noninvasive Biomarker

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Journal Article

Effect of Cu-ZSM-5 catalysts with different CuO particle size on selective catalytic oxidation of N,N-Dimethylformamide

Journal Article

Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:1 to 14:1) for simultaneous C & N removal

Journal Article

Effect of fly ash and slag on concrete: Properties and emission analyses

TAM, Khoa N. LE, Ana Catarina Jorge EVANGELISTA, Anthony BUTERA, Cuong N. N. TRAN, Ashraf TEARA

Journal Article

Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Journal Article