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Journal Article 42

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Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 3,   Pages 360-372 doi: 10.1007/s11783-011-0353-z

Abstract: The index of the antioxidant enzyme system including superoxide dismutase (SOD) and peroxidase (POD),zebrafish stressed by Cd, and content of soluble protein (SP) was sensitive to HHCB and could be used as a biomarkerJoint effects on antioxidant enzymes depended more on the effect of single Cd in the first one or two

Keywords： 1     3     4     6     7     8-hexahydro-4     6     6     7     8     8-hexamethylcyclopenta-gamma-2-benzopyran (HHCB)     cadmium (Cd)     antioxidantbiomarker     feculent water containing bedloads    

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Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 216-226 doi: 10.1007/s11684-022-0920-7

Abstract: In summary, our study demonstrated that serum tsRNA signature may serve as a novel biomarker of HCC.

Keywords： tsRNA     biomarker     hepatocarcinoma    

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EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS ENHANCED DROUGHT TOLERANCE BY ENHANCING ANTIOXIDANT

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: In addition, transgenic plants had much higher expression levels of three antioxidant enzyme genes (CATthis study demonstrates that PtrLEA7 can confer enhanced drought tolerance partially via enhancing antioxidant
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MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1,   Pages 99-105 doi: 10.1007/s11783-013-0490-7

Abstract: An alternative way is to evaluate estrogenicity through biomarker genes.MicroRNA (miRNA) is a class of regulatory gene, which has been shown to be a good biomarker for manystrong responses to E2 in the uterus of both immature and overiectomized mice, and could be a potential biomarker

Keywords： estrogen     microRNA (miRNA)     microarray     biomarker    

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Polyamines and antioxidant defense system are associated with cold tolerance in centipedegrass

Jingjing CHEN, Junyang FANG, Zhenfei GUO, Shaoyun LU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1,   Pages 129-138 doi: 10.15302/J-FASE-2017197

Abstract: Exogenous Put or Spd increased antioxidant enzyme activities and chilling tolerance.

Keywords： antioxidants     centipedegrass     chilling     photosynthesis     polyamines    

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OVEREXPRESSION OF

Tonglu WEI, Dalong GUO, Jihong LIU

Frontiers of Agricultural Science and Engineering   Pages 236-246 doi: 10.15302/J-FASE-2020368

Abstract: In addition, transgenic plants had much higher expression levels of three antioxidant enzyme genes (CATthis study demonstrates that PtrLEA7 can confer enhanced drought tolerance partially via enhancing antioxidant

Keywords： abiotic stress     antioxidant     drought     late embryogenesis abundant     Poncirus trifoliata    

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Plasma transthyretin is a nutritional biomarker in human morbidities

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 540-550 doi: 10.1007/s11684-022-0940-3

Abstract: Transthyretin (TTR) is a small liver-secreted plasma protein that shows close correlations with changes in lean body mass (LBM) during the entire human lifespan and agglomerates the bulk of nitrogen (N)-containing substrates, hence constituting the cornerstone of body building. Amino acids (AAs) dietary restriction causes inhibition of TTR production and impairs the accretion of LBM reserves. Inflammatory disorders result in cytokine-induced abrogation of TTR synthesis and urinary leakage of nitrogenous catabolites. Taken together, the data indicate that malnutrition and inflammation may similarly suppress the production of TTR through distinct and unrelated pathophysiological mechanisms while operating in concert to downsize LBM stores. The hepatic synthesis of TTR integrates both machineries, acting as a marker of reduced LBM resources still available for defense and repair processes. TTR operates as a universal surrogate analyte that allows for the grading of residual LBM capacity to reflect disease burden. Measurement of TTR is a simple, rapid, and inexpensive micro-method that may be reproduced on a daily basis, hence ideally suited for the follow-up of the most intricated clinical situations and as a reliable predictor of any morbidity outcome.

Keywords： lean body mass     nutritional status     transthyretin     malnutrition     inflammation     amyloidosis    

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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Exosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because of

Keywords： biosensor     exosome     cancer diagnosis    

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Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis

Changlin Cao, Jingxian Gu, Jingyao Zhang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 169-177 doi: 10.1007/s11684-017-0505-z

Abstract: sTREM-1) is a special form of TREM-1 that can be directly tested in human body fluids and well-known biomarkerinfections (e.g., infection), and burn-related infections. sTREM-1 is a more sensitive and specific biomarkerTherefore, sTREM-1 is a feasible biomarker for the targeted therapy and rapid and early diagnosis of

Keywords： soluble triggering receptor expressed on myeloid cells-1     infectious diseases     diagnosis and prognosis     biomarker    

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Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 723-735 doi: 10.1007/s11684-021-0905-y

Abstract: Therefore, CORO1A might be a potential biomarker and therapeutic target for ALS.

Keywords： amyotrophic lateral sclerosis     coronin-1a     autophagy     pathogenesis    

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iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic biomarker

Yiming Ma,Ting Xiao,Quan Xu,Xinxin Shao,Hongying Wang

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 278-285 doi: 10.1007/s11684-016-0453-z

Abstract: In summary, this study revealed potential molecules for future biomarker applications and provided an

Keywords： iTRAQ     secretome     colorectal cancer     TPM2    

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Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract

Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1,   Pages 108-119 doi: 10.1007/s11705-016-1553-7

Abstract: The antioxidant and antitumor effects as well as the immunomodulatory activities of crude and purifiedThe antioxidant and antitumor effects of the polyphenol extract were measured both and , and theirassays demonstrated that blueberry purified polyphenol extract (BBPP) exhibited higher antioxidant activitiesThese results indicate that BBCP has significant antioxidant and antitumor activities and that it can

Keywords： crude polyphenol extract     purified polyphenol extract     blueberry     antioxidant     antitumor     immunity    

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Inhibition of NO emission by adding antioxidant mixture in

A. PRABU,R. B. ANAND

Frontiers in Energy 2015, Volume 9, Issue 2,   Pages 238-245 doi: 10.1007/s11708-015-0356-8

Abstract: In this paper, the effect of adding an antioxidant mixture in biodiesel as fuel, in a single cylinderThe comparison showed that NO emission was reduced drastically for the test fuels with the antioxidantThe maximum reduction of 10% of NO emission was observed for the antioxidant mixture in neat biodiesel

Keywords： NO emission     antioxidants     Succinimide     N     N-dimethyl-p-phenylenediamine-dihydrochloride     N-phenyl-p-phenylenediamine    

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Sepsis biomarkers: an omics perspective

Xiao Liu, Hui Ren, Daizhi Peng

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 58-67 doi: 10.1007/s11684-014-0318-2

Abstract:

Sepsis is a common cause of death in hospitalized patients worldwide. The early detection of sepsis remains a great challenge for clinicians, and delayed diagnosis frequently undermines treatment efforts, thereby contributing to high mortality. Omics technologies allow high-throughput screening of sepsis biomarkers. This review describes currently available and novel sepsis biomarkers in the context of genomics, transcriptomics, proteomics, and metabolomics. The combination of these technologies can help refine the diagnosis of sepsis. This review paper serves as a reference for future studies that employ an integrated, multi-omics approach to disease identification.

Keywords： sepsis     biomarker     genomics     transcriptomics     proteomics     metabolomics    

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U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen

Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0880-8

Abstract: estrogenic activity and that the typical nonmonotonic dose-response relationship could be used as a novel biomarker

Keywords： miRNA     Prostate     Estradiol     Nonmonotonic dose-response     Estrogenicity     Drosha    

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Title Author Date Type Operation

Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Journal Article

Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Journal Article

EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS ENHANCED DROUGHT TOLERANCE BY ENHANCING ANTIOXIDANT

Journal Article

MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Journal Article

Polyamines and antioxidant defense system are associated with cold tolerance in centipedegrass

Jingjing CHEN, Junyang FANG, Zhenfei GUO, Shaoyun LU

Journal Article

OVEREXPRESSION OF

Tonglu WEI, Dalong GUO, Jihong LIU

Journal Article

Plasma transthyretin is a nutritional biomarker in human morbidities

Journal Article

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Journal Article

Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis

Changlin Cao, Jingxian Gu, Jingyao Zhang

Journal Article

Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Journal Article

iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic biomarker

Yiming Ma,Ting Xiao,Quan Xu,Xinxin Shao,Hongying Wang

Journal Article

Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract

Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou

Journal Article

Inhibition of NO emission by adding antioxidant mixture in

A. PRABU,R. B. ANAND

Journal Article

Sepsis biomarkers: an omics perspective

Xiao Liu, Hui Ren, Daizhi Peng

Journal Article

U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen

Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang

Journal Article