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Clinical research of traditional Chinese medicine in big data era

Junhua Zhang,Boli Zhang

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 321-327 doi: 10.1007/s11684-014-0370-y

Abstract: application of the Internet information technology in the field of healthcare, individual health records, clinicaland genomic data have been accumulated dramatically, which generates big data in medical field for clinicalsupport of big data, the defects and weakness may be overcome in the methodology of the conventional clinicalpreventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicineTo conduct clinical studies involved in big data in TCM domain, top level design is needed and should

Keywords： big data     traditional Chinese medicine     clinical evaluation     evidence based medicine    

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 358-361 doi: 10.1007/s11684-014-0348-9

Abstract:

This study proposes the ontological reconstruction of the current clinical terminology of traditionalChinese medicine (TCM).of preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation

Keywords： ontology     traditional Chinese medicine     clinical terminology    

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Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Frontiers of Medicine 2023, Volume 17, Issue 6,   Pages 1014-1029 doi: 10.1007/s11684-023-1040-8

Abstract: Traditional Chinese medicine (TCM) has played an important role in the prevention and treatment of coronavirusThe integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention

Keywords： traditional Chinese medicine     COVID-19     SARS-CoV-2     clinical evidence-based study     mechanism     integratedtraditional Chinese and Western medicine    

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Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 310-315 doi: 10.1007/s11684-014-0358-7

Abstract:

The advent of the big data era creates both opportunities and challenges for traditional Chinese medicineIt also discusses the integration of science, technology, and medicine under the guidance of the paradigmof real-world, clinical scientific research.TCM clinical diagnosis, treatment, and knowledge were traditionally limited to literature and sensationThus, these methods strongly support the real-world clinical research paradigm of TCM.

Keywords： big data     real world     clinical research     Chinese medicine     medical computing    

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Mending the schism between clinical medicine and public health, strengthening disease prevention and

Wang Longde

Strategic Study of CAE 2009, Volume 11, Issue 10,   Pages 148-152

Abstract:

This paper introduced the serious harm caused by the schism between clinicalmedicine and public health in disease prevention and control in China.strokes—an important chronic disease, to adapt to the needs of patients, and gradually adding clinicalmedicine to the modern model of disease prevention and control.These reform measures have successfully strengthened the link between clinical medicine and public health

Keywords： clinical medicine     public health     schism     disease prevention and control    

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Clinical phenotype network: the underlying mechanism for personalized diagnosis and treatment of traditionalChinese medicine

Xuezhong Zhou,Yubing Li,Yonghong Peng,Jingqing Hu,Runshun Zhang,Liyun He,Yinghui Wang,Lijie Jiang,Shiyan Yan,Peng Li,Qi Xie,Baoyan Liu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 337-346 doi: 10.1007/s11684-014-0349-8

Abstract:

Traditional Chinese medicine (TCM) investigates the clinical diagnosis and treatment regularitiesThis principle has been recognized and adhered by TCM clinical practitioners for thousands of years.clinical settings, and investigates the underlying mechanisms of TCM personalized medicine from the perspectivesof network medicine.To investigate the underlying mechanisms of TCM personalized medicine, we constructed a clinical phenotype

Keywords： personalized medicine     complex network     clinical phenotype network     traditional Chinese medicine    

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Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 157-162 doi: 10.1007/s11684-011-0128-8

Abstract: At present, clinical pathway has become one of the most important health care reform measures in manyIn this study, the authors introduced basic concepts and explored the application of the clinical pathwayof evidence-based Chinese medicine incorporated with the methodology from the concepts of management, evidence-based medicine, operational research and health economics.medicine practice in China can be based.

Keywords： evidence-based medicine     clinical pathway     methodology     concept     technical difficulty    

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Clinical decision-making by the emergency department resident physicians for critically ill patients

Tengda Xu, Jun Xu, Xuezhong Yu, Sui Ma, Zhong Wang

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 89-93 doi: 10.1007/s11684-012-0183-9

Abstract:

The application of main methodologies for clinical decision-making by residents in emergency medicalUnion Medical College Hospital of were analyzed by independent investigators who evaluated the main clinicalInclusion of clinical decision-making in medical curricula is needed to improve decision-making in critical

Keywords： clinical decision-making     emergency medicine     critically ill patient     resident     methodology    

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2000 International Conference on Life Science and Clinical Medicine

Strategic Study of CAE 2000, Volume 2, Issue 5,   Pages 93-93

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Clinical efficacy of comprehensive therapy based on traditional Chinese medicine patterns on patients

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 736-744 doi: 10.1007/s11684-021-0870-5

Abstract: Traditional Chinese medicine (TCM) presents a favorable prospect in the treatment of pneumoconiosis.A pilot study on TCM syndrome differentiation can evaluate the clinical efficacy and safety of TCM andlay a foundation for further clinical research.

Keywords： pneumoconiosis     randomized controlled trials     traditional Chinese medicine    

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Clinical features and the traditional Chinese medicine therapeutic characteristics of 293 COVID-19 inpatient

Zixin Shu, Yana Zhou, Kai Chang, Jifen Liu, Xiaojun Min, Qing Zhang, Jing Sun, Yajuan Xiong, Qunsheng Zou, Qiguang Zheng, Jinghui Ji, Josiah Poon, Baoyan Liu, Xuezhong Zhou, Xiaodong Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 760-775 doi: 10.1007/s11684-020-0803-8

Abstract: We reported the clinical features and therapeutic characteristics of moderate COVID-19 cases in Wuhanthat were treated via the integration of traditional Chinese medicine (TCM) and Western medicine., clinical treatments, laboratory tests, and outcomes of the patients.Lastly, 59% of the patients received treatment, including antiviral, antibiotics, and Chinese patent medicinecases treated via the integration of TCM herbal prescriptions and Western medicine.

Keywords： COVID-19     traditional Chinese medicine     clinical features    

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: On the basis of real-world clinical data, the study aimed to explore the effect and mechanisms of thetreatment plan of “traditional Chinese medicine (TCM) regulating liver regeneration.”The patients were divided into three groups: the modern medicine control group (MMC group), patientstreated with routine medical treatment; the control group combining traditional Chinese and Western medicine

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 352-357 doi: 10.1007/s11684-014-0351-1

Abstract:

Real world study (RWS) has become a hotspot for clinical research.Data quality plays a vital role in research achievement and other clinical research fields.In this paper, the common quality problems in the RWS of traditional Chinese medicine are discussed,

Keywords： real world study     traditional Chinese medicine     clinical and research information sharing system     data quality    

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Experience inheritance from famous specialists based on real-world clinical research paradigm of traditionalChinese medicine

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 300-309 doi: 10.1007/s11684-014-0357-8

Abstract:

The current modes of experience inheritance from famous specialists in traditional Chinese medicine(TCM) include master and disciple, literature review, clinical-epidemiology-based clinical researchThe advent of the big data era as well as the formation and practice accumulation of the TCM clinicaland practice, the research group proposes the innovation research mode based on the real-world TCM clinicaldevelopment regularity of TCM and is expected to become the main mode of experience inheritance in the clinical

Keywords： traditional Chinese medicine (TCM)     real world     clinical research paradigm     famous specialist     experience    

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xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical

Shuyang Sun,Zhiyuan Zhang

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 104-110 doi: 10.1007/s11684-016-0432-4

Abstract: We also explore the translational value of this well-annotated PDX panel in the development of co-clinical

Keywords： patient-derived xenograft models     personalized medicine     co-clinical trial     patient stratification     oral    

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Title Author Date Type Operation

Clinical research of traditional Chinese medicine in big data era

Junhua Zhang,Boli Zhang

Journal Article

Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Journal Article

Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Journal Article

Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Journal Article

Mending the schism between clinical medicine and public health, strengthening disease prevention and

Wang Longde

Journal Article

Clinical phenotype network: the underlying mechanism for personalized diagnosis and treatment of traditionalChinese medicine

Xuezhong Zhou,Yubing Li,Yonghong Peng,Jingqing Hu,Runshun Zhang,Liyun He,Yinghui Wang,Lijie Jiang,Shiyan Yan,Peng Li,Qi Xie,Baoyan Liu

Journal Article

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Journal Article

Clinical decision-making by the emergency department resident physicians for critically ill patients

Tengda Xu, Jun Xu, Xuezhong Yu, Sui Ma, Zhong Wang

Journal Article

2000 International Conference on Life Science and Clinical Medicine

Journal Article

Clinical efficacy of comprehensive therapy based on traditional Chinese medicine patterns on patients

Journal Article

Clinical features and the traditional Chinese medicine therapeutic characteristics of 293 COVID-19 inpatient

Zixin Shu, Yana Zhou, Kai Chang, Jifen Liu, Xiaojun Min, Qing Zhang, Jing Sun, Yajuan Xiong, Qunsheng Zou, Qiguang Zheng, Jinghui Ji, Josiah Poon, Baoyan Liu, Xuezhong Zhou, Xiaodong Li

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Journal Article

Experience inheritance from famous specialists based on real-world clinical research paradigm of traditionalChinese medicine

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Journal Article

xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical

Shuyang Sun,Zhiyuan Zhang

Journal Article