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Molecular alterations and clinical relevance in esophageal squamous cell carcinoma
Li Shang, Mingrong Wang
Frontiers of Medicine 2013, Volume 7, Issue 4, Pages 401-410 doi: 10.1007/s11684-013-0286-y
Keywords: esophageal squamous cell carcinoma (ESCC) early detection molecular classification molecular markers
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology
Huating Li, Jing Zhang, Weiping Jia
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 25-30 doi: 10.1007/s11684-013-0244-8
Keywords: FGF21 metabolism pharmacology physiology clinical relevance
Factors affecting early embryonic development in cattle: relevance for bovine cloning
Yanna DANG, Kun ZHANG
Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1, Pages 33-41 doi: 10.15302/J-FASE-2018228
Female infertility represents a major challenge for improving the production efficiency in the dairy industry. Historically, fertility has declined whereas milk yield has increased tremendously due to intensive genetic selection. evidence reveals about 60% pregnancy loss takes place during the first month following fertilization. Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a large proportion of cloned embryos fail to develop beyond peri-implantation stage. Oocyte quality is of utmost importance for the early embryo to develop to term for both fertilized and cloned embryos. Epigenetic reprogramming is a key process occurring after fertilization and critical roles of epigenetic modifiers during preimplantation development are now clear. Incomplete epigenetic reprogramming is believed to be a major limitation to cloning efficiency. Treatment of cloned embryos with epigenetic modifying drugs (e.g., Trichostatin A) could greatly improve cloning efficiency in both mice and cattle. Recently, the rapid progress in high-throughput sequencing technologies has enabled detailed deciphering of the molecular mechanisms underlying these events. The robust efficiency of genomic editing tools also presents an alternative approach to the functional annotation of genes critical to early development.
Keywords: bovine cloning embryo development somatic cell nuclear transfer X-inactive specific transcript
Cardiac Remote Conditioning and Clinical Relevance: All Together Now! Review
Kristin Luther,Yang Song,Yang Wang,Xiaoping Ren,W. Keith Jones
Engineering 2015, Volume 1, Issue 4, Pages 490-499 doi: 10.15302/J-ENG-2015117
Keywords: conditioning non-ischemic conditioning peripheral nociceptive stimulus neural and molecular mechanism clinical
The relevance of James Lovelock’s research and philosophy to environmental science and academia
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1639-7
Keywords: Academic independence Climate change Electron capture detector Environmental equilibrium Global warming Homeostasis
Ontological reconstruction of the clinical terminology of traditional Chinese medicine
Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui
Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 358-361 doi: 10.1007/s11684-014-0348-9
This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation
Keywords: ontology traditional Chinese medicine clinical terminology
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 527-533 doi: 10.1007/s11684-022-0967-5
Keywords: orthotopic heart transplant tricuspid regurgitation clinical impact biatrial heart transplantation
Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment
Tianhua Xu, Zitong Sheng, Li Yao
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 340-348 doi: 10.1007/s11684-017-0570-3
Keywords: obesity-related glomerulopathy pathogenesis pathologic clinical characteristics
Coronavirus disease 2019 (COVID-19): a clinical update
Min Zhou, Xinxin Zhang, Jieming Qu
Frontiers of Medicine 2020, Volume 14, Issue 2, Pages 126-135 doi: 10.1007/s11684-020-0767-8
Keywords: coronavirus disease 2019 epidemiology pathology radiology clinical characteristics treatment
Hypertension in patients with CKD in China: clinical characteristics and management
Guangyan Cai, Xiangmei Chen
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 307-309 doi: 10.1007/s11684-017-0578-8
Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 551-573 doi: 10.1007/s11684-022-0928-z
Keywords: HCC bone osteotropism clinical basic researches advances
Heterogeneity of the tumor immune microenvironment and clinical interventions
Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 617-648 doi: 10.1007/s11684-023-1015-9
Keywords: Heterogeneity tumor immune
Biological properties and clinical applications of berberine
Danyang Song, Jianyu Hao, Daiming Fan
Frontiers of Medicine 2020, Volume 14, Issue 5, Pages 564-582 doi: 10.1007/s11684-019-0724-6
Keywords: berberine Coptis chinensis pharmacological properties mechanism clinical applications
Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis
Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu
Frontiers of Medicine 2019, Volume 13, Issue 4, Pages 411-419 doi: 10.1007/s11684-018-0659-3
Keywords: rheumatoid arthritis gene clinical markers therapy
Anatomy and embryology of umbilicus in newborns: a review and clinical correlations
Abdelmonem A. Hegazy
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 271-277 doi: 10.1007/s11684-016-0457-8
Keywords: anatomy embryology newborns umbilicus
Title Author Date Type Operation
Molecular alterations and clinical relevance in esophageal squamous cell carcinoma
Li Shang, Mingrong Wang
Journal Article
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology
Huating Li, Jing Zhang, Weiping Jia
Journal Article
Factors affecting early embryonic development in cattle: relevance for bovine cloning
Yanna DANG, Kun ZHANG
Journal Article
Cardiac Remote Conditioning and Clinical Relevance: All Together Now!
Kristin Luther,Yang Song,Yang Wang,Xiaoping Ren,W. Keith Jones
Journal Article
The relevance of James Lovelock’s research and philosophy to environmental science and academia
Journal Article
Ontological reconstruction of the clinical terminology of traditional Chinese medicine
Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui
Journal Article
The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant
Journal Article
Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment
Tianhua Xu, Zitong Sheng, Li Yao
Journal Article
Coronavirus disease 2019 (COVID-19): a clinical update
Min Zhou, Xinxin Zhang, Jieming Qu
Journal Article
Hypertension in patients with CKD in China: clinical characteristics and management
Guangyan Cai, Xiangmei Chen
Journal Article
Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives
Journal Article
Biological properties and clinical applications of berberine
Danyang Song, Jianyu Hao, Daiming Fan
Journal Article
Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis
Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu
Journal Article