Resource Type

Journal Article 2

Year

2016 1

2010 1

Keywords

hemodynamics 2

bronchiectasis 1

guidelines 1

pulmonary hypertension 1

sepsis 1

septic shock 1

open ︾

Search scope:

排序: Display mode:

Clinical characteristics of pulmonary hypertension in bronchiectasis

Lan Wang,Sen Jiang,Jingyun Shi,Sugang Gong,Qinhua Zhao,Rong Jiang,Ping Yuan,Bigyan Pudasaini,Jing He,Zhicheng Jing,Jinming Liu

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 336-344 doi: 10.1007/s11684-016-0461-z

Abstract: hemodynamic impairment can occur in patients with bilateral bronchiectasis, and PAH therapy might improve hemodynamics

Keywords: bronchiectasis     hemodynamics     pulmonary hypertension    

Review of recent guidelines for the management of severe sepsis and septic shock

Jin-Nong ZHANG MD, Bo PENG BA, Jamile WOODS MD, Wei PENG MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 54-58 doi: 10.1007/s11684-010-0008-7

Abstract: Severe sepsis and septic shock affect millions of patients and are major causes of mortality worldwide. Advancements in treatment and disease management led to a decline in in-hospital mortality from 27.8% (1979–1984) to 17.9% (1995 to 2000). In this article, we systemically review recent guidelines for the management of severe sepsis and septic shock published in 2008 by the International Surviving Sepsis Campaign Guidelines Committee. The 2008 Surviving Sepsis guidelines recommend protocolized resuscitation with goals to maintain central venous pressure≥8–12mmHg, mean arterial pressure≥65mmHg, urine output≥0.5mL·kg·h and central venous oxygen saturation≥70% (or mixed venous≥65%). Further fluid administration, transfusion of packed red blood cells to achieve a hematocrit of≥30% and/or infusion of dobutamine max 20µg·kg·min are advised if venous O saturations remain below 70%. In patients with decreased ventricular compliance or mechanical ventilation, a target central venous pressure of 12–15mmHg is recommended. Intravenous antibiotic administration within the first hour of recognizing severe sepsis and septic shock is essential, while use of corticosteroids in sepsis is controversial. The mechanisms by which activated protein C improves clinical outcomes in sepsis are unknown. Therapy with activated protein C is approved for patients with severe sepsis and an increased risk of death [Acute Physiology and Chronic Health Evaluation II (APACHE II)>25]. Bicarbonate therapy is discouraged. Intravenous insulin should be used to control hyperglycemia in patients with severe sepsis following stabilization in the intensive care unit.

Keywords: sepsis     septic shock     hemodynamics     guidelines    

Title Author Date Type Operation

Clinical characteristics of pulmonary hypertension in bronchiectasis

Lan Wang,Sen Jiang,Jingyun Shi,Sugang Gong,Qinhua Zhao,Rong Jiang,Ping Yuan,Bigyan Pudasaini,Jing He,Zhicheng Jing,Jinming Liu

Journal Article

Review of recent guidelines for the management of severe sepsis and septic shock

Jin-Nong ZHANG MD, Bo PENG BA, Jamile WOODS MD, Wei PENG MD, PhD,

Journal Article