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Alternative splicing of inner-ear-expressed genes

Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 250-257 doi: 10.1007/s11684-016-0454-y

Abstract: Inner-ear-specific gene splicing is necessary to establish the identity and maintain the function ofthe inner ear.For example, exon 68 of Cadherin 23 (Cdh23) gene is subject to inner-ear-specific alternativesplicing, and as a result, Cdh23(+68) is only expressed in inner ear hair cells.Despite the advances in this field, the regulation of alternative splicing in the inner ear remains elusive

Keywords: alternative splicing     inner ear     hearing loss     hair cells    

Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium

Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 330-335 doi: 10.1007/s11684-016-0459-6

Abstract: in the nuclei of the cochlear epithelium in all three turns and could be clearly seen in outer and inner

Keywords: polycomb repressive complex     Ezh2     expression     inner ear     cochlea     development    

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract:

Sensory hair cells in the inner ear are responsible for sound recognition.presents the current understanding of the Wnt and Notch signaling pathways in the auditory portion of the innerear and discusses the possibilities of controlling these pathways with the hair cell fate determiner

Keywords: inner ear     cochlea     hair cell     regeneration     Wnt     Notch     signaling pathways    

Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 705-712 doi: 10.1007/s11684-019-0703-y

Abstract: prosensory domain and in the differentiation of hair cells (HCs) and supporting cells during mouse innerear development; however, the relationship between the two signaling pathways in the mouse cochlea remains

Keywords: inner ear     cochlear     Wnt     Notch     Lgr5     auditory system    

Effects of inner sleeves on the inner frictional resistance of open-ended piles driven into sand

Janaka J. KUMARA,Yoshiaki KIKUCHI,Takashi KURASHINA,Takahiro YAJIMA

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 4,   Pages 499-505 doi: 10.1007/s11709-016-0335-0

Abstract: In open-ended piles, inner friction is developed between inner pile shaft and the inner soil.Inner frictional resistance depends largely on the degree of soil plugging, which is influenced by manyIn this paper, effects of inner sleeves on inner frictional resistance are discussed.The results suggest that inner frictional resistance, increases with sleeve height, linearly and

Keywords: bearing capacity     inner frictional resistance     inner sleeve     open-ended piles     soil plugging    

Driving mechanisms of desertification process in the Horqin Sandy Land-a case study in Zhalute Banner, Inner

TANG Haiping, CHEN Yufu, LI Xinyu

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 4,   Pages 487-493 doi: 10.1007/s11783-008-0061-5

Abstract: were examined to understand the driving mechanisms of the desertification process in Zhalute Banner, Inner

Studies on several dynamics problems in the design of the explosion water-well with steel-inner

Gu Wenbin,Chen Xueping,Liu Jianqing

Strategic Study of CAE 2013, Volume 15, Issue 10,   Pages 71-79

Abstract: dynamics problems in the design of explosion well, such as the influence of thickness of the steel-innerThe biggest force and deformation of the inner wall of the steel-inner appears below the horizontal lineof the center of the charge, when the thickness of steel-inner reaches 50 mm.The equivalent plastic strain where is 1.6 m far away from the bottom of steel-inner can attain 0.16When the thickness of the steel-inner is 20 mm and the thickness of concrete cofferdam is over 0.35 m

Keywords: design of explosion water-well with steel-inner     dynamics analysis     stress and strain response     numerical    

A High-Resolution Measurement Method for Inner and Outer 3D Surface Profiles of Laser Fusion Targets

Weiqian Zhao,Zihao Liu,Lirong Qiu,

Engineering doi: 10.1016/j.eng.2024.05.016

Abstract: The high-resolution and nondestructive co-reference measurement of the inner and outer three-dimensionalstudy, we propose a laser differential confocal (LDC)–atomic force probe (AFP) method to measure the innerNondestructive and co-reference measurements of the inner profile of a target were achieved using theprofile measurement were 0.5 and 1.3 nm, while the respective axial and lateral resolutions of the innerThe repeatabilities of the root-mean-square deviation measurements for the outer and inner profiles of

Keywords: Laser fusion targets     LDC–AFP     High-resolution     Nondestructive     Co-reference    

Polydimethylsiloxane (PDMS) Composite Membrane Fabricated on the Inner Surface of a Ceramic Hollow Fiber Article

Ziye Dong, Haipeng Zhu, Yingting Hang, Gongping Liu, Wanqin Jin

Engineering 2020, Volume 6, Issue 1,   Pages 89-99 doi: 10.1016/j.eng.2019.10.012

Abstract: margin-top:6.0pt;margin:0cm 0cm 0.0001pt;text-align:justify;">The fabrication of a separation layer on the innerThis work reports on the fabrication of a polydimethylsiloxane (PDMS) composite membrane on the innerThe formation mechanism for the deposition of the PDMS layer onto the inner surface of the ceramic HFThe optimized inner surface of the PDMS/ceramic HF composite membranes with a thin and defect-free separationThe facile coating/cross- flow methodology proposed here shows great potential for fabricating inner-surface

Keywords: Ceramic hollow fiber Inner membrane     Pervaporation     Polydimethylsiloxane     Butanol    

The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia,

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 191-200 doi: 10.15302/J-FASE-2014029

Abstract: Since the birth of the first cloned sheep, somatic cell nuclear transfer technology has been successfully used to clone a variety of mammals. Cloned livestock have no apparent health risks, and the quality and safety of the cloned animal products are similar to non-cloned animals. The social behavior and environmental adaptability of postnatal cloned animals, especially when used for grassland farm production purposes, is unknown. In the present study, the cloned Dorper sheep equipped with GPS location devices were free-grazed in a harsh natural environment similar to conditions commonly experienced by Mongolian sheep. The main findings of this research were as follows. (1) Under free-grazing conditions, the cloned sheep showed excellent climatic and ecological adaptability. In extreme temperature conditions ranging from -30 to 40°C, the cloned sheep maintained acceptable body condition and behaved as other sheep. (2) The cloned sheep quickly adapted from a herd feeding strategy to the harsh environment and quickly exhibited a grazing regimen as other free-grazing sheep. (3) The cloned sheep exhibited free-grazing patterns and social behavior as other sheep. (4) The cloned sheep in the harsh environment thrived and produced healthy lambs. Overall, the cloned Dorper sheep exhibited excellent ecological adaptation, which is an important consideration for breeding meat sheep by cloning. The Dorper sheep readily adapted to the free-grazing conditions on the Mongolian plateau grassland, which attests to their ability to withstand harsh environmental conditions.

Keywords: somatic cell nuclear transfer     free-grazing synchronization     Dorper sheep     cloned animal ecology    

Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate moisture food

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 346-350 doi: 10.1007/s11705-009-0256-8

Abstract: The formation of both a hard inner-layer and agglomerated particles in the inner matrix was observedloss and sucrose crystallization were mainly responsible for the formation of the crusty intermediate inner

Keywords: inner-layer     agglomerated     IMF     moisture migration     crystallization    

Microfabricated Atomic Vapor Cells with Multi-Optical Channels Based on an Innovative Inner-Sidewall Article

Mingzhi Yu, Yao Chen, Yongliang Wang, Xiangguang Han, Guoxi Luo, Libo Zhao, Yanbin Wang, Yintao Ma, Shun Lu, Ping Yang, Qijing Lin, Kaifei Wang, Zhuangde Jiang

Engineering 2024, Volume 35, Issue 4,   Pages 46-55 doi: 10.1016/j.eng.2023.08.016

Abstract: fabricating multi-optical-channel atomic vapor cells and an innovative method for batch processing the innerSurface characterization and transmittance tests demonstrate that the processed inner sidewalls satisfy

Keywords: Microfabricated atomic vapor cells     Inner-sidewall molding     Multiple optical channels     Quantum sensing    

Wheat ear growth modeling based on a polygon Special Feature on Virtual Reality-Research Articl

Jun-xiao XUE, Chen-yang SUN, Jun-jin CHENG, Ming-liang XU, Ya-fei LI, Shui YU

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 9,   Pages 1175-1184 doi: 10.1631/FITEE.1800702

Abstract: Visual inspection of wheat growth has been a useful tool for understanding and implementing agricultural techniques and a way to accurately predict the growth status of wheat yields for economists and policy decision makers. In this paper, we present a polygonal approach for modeling the growth process of wheat ears. The grain, lemma, and palea of wheat ears are represented as editable polygonal models, which can be re-polygonized to detect collision during the growth process. We then rotate and move the colliding grain to resolve the collision problem. A linear interpolation and a spherical interpolation are developed to simulate the growth of wheat grain, performed in the process of heading and growth of wheat grain. Experimental results show that the method has a good modeling effect and can realize the modeling of wheat ears at different growth stages.

Keywords: Visual inspection     Virtual crop     Three-dimensional modeling    

Inner strain determination of three-dimensional braided preforms with co-braided optical fiber sensors

LI Xianghua, LIU Xiaohui, YUAN Shenfang

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 4,   Pages 416-420 doi: 10.1007/s11465-008-0062-x

Abstract: The experimental characterization of three-dimensional (3-D) braided composites is extremely important for their design and analysis. Because of their desirable attributes and outstanding performance, optical fiber sensors (OFSs) can be embedded to monitor mechanical properties of textile composites. This paper discusses two techniques to incorporate different OFSs into 3-D braided composite preforms. The operating principle of various sensor systems is first conducted. Experiments using Michelson interferometers, FBG sensors, and micro-bend sensors are performed to verify the concept of the proposed method. Strain curves of various OFSs tests are finally compared, and they all exhibit good linearity.

Keywords: different     experimental characterization     three-dimensional     composite     micro-bend    

Cyclic behavior of stiffened joints between concrete-filled steel tubular column and steel beam with narrow outer diaphragm and partial joint penetration welds

Chunyan QUAN,Wei WANG,Jian ZHOU,Rong WANG

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 3,   Pages 333-344 doi: 10.1007/s11709-016-0357-7

Abstract: On the contrary, the inner diaphragm and inner stiffeners had limited impacts on the hysteretic behavior

Keywords: narrow outer diaphragm     concrete-filled tubular column     joint     inner and outer stiffening     cyclic behavior    

Title Author Date Type Operation

Alternative splicing of inner-ear-expressed genes

Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu

Journal Article

Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium

Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Journal Article

Effects of inner sleeves on the inner frictional resistance of open-ended piles driven into sand

Janaka J. KUMARA,Yoshiaki KIKUCHI,Takashi KURASHINA,Takahiro YAJIMA

Journal Article

Driving mechanisms of desertification process in the Horqin Sandy Land-a case study in Zhalute Banner, Inner

TANG Haiping, CHEN Yufu, LI Xinyu

Journal Article

Studies on several dynamics problems in the design of the explosion water-well with steel-inner

Gu Wenbin,Chen Xueping,Liu Jianqing

Journal Article

A High-Resolution Measurement Method for Inner and Outer 3D Surface Profiles of Laser Fusion Targets

Weiqian Zhao,Zihao Liu,Lirong Qiu,

Journal Article

Polydimethylsiloxane (PDMS) Composite Membrane Fabricated on the Inner Surface of a Ceramic Hollow Fiber

Ziye Dong, Haipeng Zhu, Yingting Hang, Gongping Liu, Wanqin Jin

Journal Article

The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia,

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Journal Article

Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate moisture food

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Journal Article

Microfabricated Atomic Vapor Cells with Multi-Optical Channels Based on an Innovative Inner-Sidewall

Mingzhi Yu, Yao Chen, Yongliang Wang, Xiangguang Han, Guoxi Luo, Libo Zhao, Yanbin Wang, Yintao Ma, Shun Lu, Ping Yang, Qijing Lin, Kaifei Wang, Zhuangde Jiang

Journal Article

Wheat ear growth modeling based on a polygon

Jun-xiao XUE, Chen-yang SUN, Jun-jin CHENG, Ming-liang XU, Ya-fei LI, Shui YU

Journal Article

Inner strain determination of three-dimensional braided preforms with co-braided optical fiber sensors

LI Xianghua, LIU Xiaohui, YUAN Shenfang

Journal Article

Cyclic behavior of stiffened joints between concrete-filled steel tubular column and steel beam with narrow outer diaphragm and partial joint penetration welds

Chunyan QUAN,Wei WANG,Jian ZHOU,Rong WANG

Journal Article