Resource Type

Journal Article 39

Year

2023 2

2022 5

2021 1

2020 2

2019 6

2018 2

2017 3

2016 1

2015 4

2014 1

2013 1

2012 4

2011 2

2010 4

open ︾

Keywords

acute myeloid leukemia 9

acute promyelocytic leukemia 7

leukemia 7

acute lymphoblastic leukemia 5

imatinib 3

mutation 3

Philadelphia chromosome 2

chronic myeloid leukemia 2

dasatinib 2

hematopoiesis 2

immunotherapy 2

prognosis 2

relapse 2

21) 1

RUNX1 1

ABT-199 1

AML 1

AML1-ETO 1

B cell acute lymphoblastic leukemia 1

B cells 1

open ︾

Search scope:

排序: Display mode:

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 45-52 doi: 10.1007/s11684-011-0117-y

Abstract:

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia.directly degrades the PML-RARα fusion transcript, leading to the differentiation and apoptosis of leukemiacells and the potential eradication of APL leukemia-initiating cells (LICs), thus making the diseasea potentially curable type of leukemia.

Keywords: acute promyelocytic leukemia     arsenic     all-trans retinoic acid     survival    

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 356-362 doi: 10.1007/s11684-010-0220-5

Abstract: Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell.

Keywords: acute myeloid leukemia     mutations     risk stratification    

Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era

Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 204-211 doi: 10.1007/s11684-012-0202-x

Abstract:

We evaluated the outcomes of chronic myeloid leukemia (CML) patients in three clinical phases, namely

Keywords: imatinib     chronic myeloid leukemia     complete cytogenetic response    

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: Hence, we aimed to explore its definite role in the development of acute myeloid leukemia (AML) and emphasize

Keywords: acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

hematopoietic stem cell transplantation to nilotinib and dasatinib for adult patients with chronic myelogenous leukemia

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 304-311 doi: 10.1007/s11684-015-0400-4

Abstract: tyrosine kinase inhibitor (TKI) era, imatinib is the first-line therapy for patients with chronic myeloid leukemia

Keywords: chronic myeloid leukemia     imatinib     dasatinib     nilotinib     allogeneic hematopoietic stem cell transplantation    

Molecular mechanisms of leukemia-associated protein degradation

Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 363-370 doi: 10.1007/s11684-010-0210-7

Abstract: Transcription factors and kinases such as retinoic acid receptor-alpha (RARα), acute myeloid leukemiaAbnormalities in these proteins may cause the dysregulation of hematopoiesis and even the occurrence of leukemia, we will summarize the recent advances in the understanding of the roles of protein degradation in leukemia

Keywords: protein degradation     leukemia     chemical biology     transcription factors     oncoprotein    

Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 416-420 doi: 10.1007/s11684-012-0224-4

Abstract:

Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acutelymphoblastic leukemia (B-ALL).This novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL).Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblasticleukemia with poor prognosis.

Keywords: acute lymphoblastic leukemia     early T precursor     prognosis    

methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia

Yuting Tan,Han Liu,Saijuan Chen

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 412-420 doi: 10.1007/s11684-015-0423-x

Abstract:

Genetic mutations are considered to drive the development of acute myeloid leukemia (AML).mutations alone may only transform hematopoietic stem cells into pre-LSCs without causing the full-blown leukemia

Keywords: preleukemic stem cell     acute myeloid leukemia     relapse     DNMT3A    

Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 518-526 doi: 10.1007/s11684-022-0958-6

Abstract: Venous thromboembolism (VTE) is a complication in children with acute lymphoblastic leukemia (ALL).

Keywords: acute lymphoblastic leukemia     child     venous thromboembolism     epidemiology     clinical characteristic     risk    

unmanipulated allogeneic transplantation could be used as a salvage option for patients with relapsed acute leukemia

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 728-739 doi: 10.1007/s11684-021-0833-x

Abstract: However, little is known about the efficacy of HSCT2 in patients with relapsed/refractory acute leukemia

Keywords: second hematopoietic stem cell transplantation     acute leukemia     relapse     chemotherapy     modified donor    

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 685-698 doi: 10.1007/s11684-022-0942-1

Abstract: However, little is known about the role of ACSL5 in acute myeloid leukemia (AML).

Keywords: acute myeloid leukemia     acyl-CoA synthetase long chain family member 5     Wnt3a     palmitoylation     ABT-199    

Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 254-258 doi: 10.1007/s11684-014-0319-1

Abstract: Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which

Keywords: mantle cell lymphoma     bendamustine     cardiogenic shock    

CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acute lymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 139-149 doi: 10.1007/s11684-021-0835-8

Abstract: shown remarkable efficacy in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia

Keywords: B-cell acute lymphoblastic leukemia     bispecific antibody     trispecific antibody     CD19     CD20    

AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches

Megan A. Hatlen, Lan Wang, Stephen D. Nimer

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 248-262 doi: 10.1007/s11684-012-0206-6

Abstract: which is present in approximately 4%–12% of adult and 12%–30% of pediatric acute myeloid leukemia

Keywords: AML1-ETO     mouse model     leukemia     t(8     21)     pathway hits     mutation     hematopoiesis     Kasumi-1     CD34+    

Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of

Zhan Su, Fengyu Wu, Weiyu Hu, Xiaodan Liu, Shaoling Wu, Xianqi Feng, Zhongguang Cui, Jie Yang, Zhenguang Wang, Hongzai Guan, Hongguo Zhao, Wei Wang, Chunting Zhao, Jun Peng

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 440-444 doi: 10.1007/s11684-017-0523-x

Abstract:

Philadelphia chromosome-positive acute myeloid leukemia is controversial and difficult to distinguishfrom the blast phase of chronic myeloid leukemia.As a myeloid neoplasm, rare cases of this leukemia manifest multiple soft-tissue tumors or bone lytictogether with complex chromosome abnormalities, a diagnosis of Philadelphia-positive acute myeloid leukemia

Keywords: Philadelphia chromosome     acute myeloid leukemia     mass     osteolysis     positron emission tomography    

Title Author Date Type Operation

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Journal Article

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Journal Article

Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era

Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen

Journal Article

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Journal Article

hematopoietic stem cell transplantation to nilotinib and dasatinib for adult patients with chronic myelogenous leukemia

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Journal Article

Molecular mechanisms of leukemia-associated protein degradation

Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,

Journal Article

Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Journal Article

methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia

Yuting Tan,Han Liu,Saijuan Chen

Journal Article

Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese

Journal Article

unmanipulated allogeneic transplantation could be used as a salvage option for patients with relapsed acute leukemia

Journal Article

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Journal Article

Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu

Journal Article

CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acute lymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia

Journal Article

AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches

Megan A. Hatlen, Lan Wang, Stephen D. Nimer

Journal Article

Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of

Zhan Su, Fengyu Wu, Weiyu Hu, Xiaodan Liu, Shaoling Wu, Xianqi Feng, Zhongguang Cui, Jie Yang, Zhenguang Wang, Hongzai Guan, Hongguo Zhao, Wei Wang, Chunting Zhao, Jun Peng

Journal Article