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Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 217-226 doi: 10.1007/s11684-014-0326-2
This study was designed to investigate the contribution of miRNA-122-binding site polymorphism at
Keywords: hepatocellular carcinoma (HCC) interaction miRNA-122-binding site IL-1A rs3783553 hepatitis B virus (
MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus
Lingyan HOU, Yun LU, Ying LI, Li LI
Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1, Pages 99-105 doi: 10.1007/s11783-013-0490-7
Keywords: estrogen microRNA (miRNA) microarray biomarker
Tao Rui,Xueyou Zhang,Shi Feng,Haitao Huang,Shaowei Zhan,Haiyang Xie,Lin Zhou,Shusen Zheng,Qi Ling,
Engineering 2022, Volume 16, Issue 9, Pages 162-175 doi: 10.1016/j.eng.2021.07.020
Keywords: Hepatocellular carcinoma miRNA cluster Exosome Multi-omics
Inflammation and liver tumorigenesis
Beicheng Sun, Michael Karin
Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 242-254 doi: 10.1007/s11684-013-0256-4
Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a major cause of liver cancer. This review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss recent advances in understanding the chronic hepatitis-liver cancer link based on hot spots in liver cancer research, including cellular interaction, cytokines, microRNA and stem cells. All of these mechanisms should be taken into consideration because they are crucial for the development of more efficacious therapeutic strategies for preventing and treating human chronic hepatitis and hepatocellular carcinoma.
Keywords: hepatocellular carcinoma hepatitis cytokine stem cell miRNA
Haifa RAJHI,Daniel PUYOL,Mirna C. MARTÍNEZ,Emiliano E. DÍAZ,José L. SANZ
Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 3, Pages 513-521 doi: 10.1007/s11783-015-0777-y
Keywords: dark fermentation biohydrogen wastewaters vacuum
miRNAs in non-alcoholic fatty liver disease
Zhen He,Cheng Hu,Weiping Jia
Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 389-396 doi: 10.1007/s11684-016-0468-5
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver cirrhosis and hepatocellular carcinoma and is a considerable threat to public health. miRNAs are important post-transcriptional regulators of gene expression, and the dysregulation of miRNAs is involved in various biological processes in the liver, including lipid homeostasis, inflammation, apoptosis, and cell proliferation. Recently, a number of studies have described the association between miRNAs and NAFLD progression and have shown that circulating miRNAs reflect histological changes in the liver. Therefore, circulating miRNAs have potential use for the evaluation of NAFLD severity. In this review, we discuss the involvement of miRNAs in NAFLD pathogenesis and the key role of miRNAs in the screening, diagnosis, and staging of NAFLD.
Keywords: nonalcoholic fatty liver disease nonalcoholic steatohepatitis hepatocellular carcinoma miRNA
MicroRNAs and their roles in osteoclast differentiation
Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo
Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 414-419 doi: 10.1007/s11684-011-0168-0
Keywords: miRNA osteoclast differentiation antagomirs
U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen
Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang
Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0880-8
Keywords: miRNA Prostate Estradiol Nonmonotonic dose-response Estrogenicity Drosha
Nan Ding,Jiafei Xi,Yanming Li,Xiaoyan Xie,Jian Shi,Zhaojun Zhang,Yanhua Li,Fang Fang,Sihan Wang,Wen Yue,Xuetao Pei,Xiangdong Fang
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 297-310 doi: 10.1007/s11684-016-0452-0
Keywords: erythroid differentiation hematopoietic stem cell RNA-seq miRNA lncRNA
Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering
Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu
Engineering 2017, Volume 3, Issue 1, Pages 3-15 doi: 10.1016/J.ENG.2017.01.005
Tissue engineering is a relatively new but rapidly developing field in the medical sciences. Noncoding RNAs (ncRNAs) are functional RNA molecules without a protein-coding function; they can regulate cellular behavior and change the biological milieu of the tissue. The application of ncRNAs in tissue engineering is starting to attract increasing attention as a means of resolving a large number of unmet healthcare needs, although ncRNA-based approaches have not yet entered clinical practice. In-depth research on the regulation and delivery of ncRNAs may improve their application in tissue engineering. The aim of this review is: to outline essential ncRNAs that are related to tissue engineering for the repair and regeneration of nerve, skin, liver, vascular system, and muscle tissue; to discuss their regulation and delivery; and to anticipate their potential therapeutic applications.
Keywords: Tissue engineering Noncoding RNAs MicroRNAs Nerve Skin Liver Vascular system Muscle
Title Author Date Type Operation
Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with
Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Journal Article
MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus
Lingyan HOU, Yun LU, Ying LI, Li LI
Journal Article
MiR-516a-3p is a Novel Mediator of Hepatocellular Carcinoma Oncogenic Activity and Cellular Metabolism
Tao Rui,Xueyou Zhang,Shi Feng,Haitao Huang,Shaowei Zhan,Haiyang Xie,Lin Zhou,Shusen Zheng,Qi Ling,
Journal Article
Vacuum promotes metabolic shifts and increases biogenic hydrogen production in dark fermentation systems
Haifa RAJHI,Daniel PUYOL,Mirna C. MARTÍNEZ,Emiliano E. DÍAZ,José L. SANZ
Journal Article
MicroRNAs and their roles in osteoclast differentiation
Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo
Journal Article
U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen
Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun, Xingfan Tang
Journal Article
Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation
Nan Ding,Jiafei Xi,Yanming Li,Xiaoyan Xie,Jian Shi,Zhaojun Zhang,Yanhua Li,Fang Fang,Sihan Wang,Wen Yue,Xuetao Pei,Xiangdong Fang
Journal Article