Resource Type

Journal Article 1

Year

2021 1

Keywords

H. sinensis mycelium 1

epithelial−mesenchymal transition 1

midkine 1

pulmonary fibrosis 1

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sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 313-329 doi: 10.1007/s11684-020-0737-1

Abstract: In addition, the expression levels of midkine are increased in the lungs of the BLM-induced group.Further analysis of the results indicates that the mRNA level of midkine correlated positively with EMTThe activation of midkine related signaling pathway is ameliorated following HSM treatment, whereas thisextract also caused an effective attenuation of the induction of EMT (caused by midkine overexpressionResults further confirm that oral medication of HSM disrupted the midkine pathway .

Keywords： epithelial−mesenchymal transition     H. sinensis mycelium     midkine     pulmonary fibrosis    

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sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Journal Article