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Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 132-142 doi: 10.1007/s11684-022-0938-x

Abstract: RFC4 knockdown induced G2/M cell cycle arrest and inhibited NPC cell proliferation in vitro anddownstream target of RFC4, and the overexpression of HOXA10 attenuated the silencing of RFC4-induced cell proliferationFor the first time, this study reveals that RFC4 is required for NPC cell proliferation and may play

Keywords: nasopharyngeal carcinoma     WGCNA     RFC4     proliferation    

is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation

Lan Wang,Jueheng Wu,Jie Yuan,Xun Zhu,Hongmei Wu,Mengfeng Li

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 41-51 doi: 10.1007/s11684-016-0429-z

Abstract: Results showed that siRNA silencing of MID2 expression significantly reduced MCF-7 and MDA-MB-231 cell proliferation

Keywords: breast cancer     MID2     proliferation     overall survival     xenograft    

The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis

Patrick A. Carroll, Brian W. Freie, Haritha Mathsyaraja, Robert N. Eisenman

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 412-425 doi: 10.1007/s11684-018-0650-z

Abstract:

Transcription factor networks have evolved in order to control, coordinate, and separate, the functions of distinct network modules spatially and temporally. In this review we focus on the MYC network (also known as the MAX-MLX Network), a highly conserved super-family of related basic-helix-loop-helix-zipper (bHLHZ) proteins that functions to integrate extracellular and intracellular signals and modulate global gene expression. Importantly the MYC network has been shown to be deeply involved in a broad spectrum of human and other animal cancers. Here we summarize molecular and biological properties of the network modules with emphasis on functional interactions among network members. We suggest that these network interactions serve to modulate growth and metabolism at the transcriptional level in order to balance nutrient demand with supply, to maintain growth homeostasis, and to influence cell fate. Moreover, oncogenic activation of MYC and/or loss of a MYC antagonist, results in an imbalance in the activity of the network as a whole, leading to tumor initiation, progression and maintenance.

Keywords: network     transcription     cancer     MYC     MAX     MLX    

Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

Frontiers in Energy 2022, Volume 16, Issue 1,   Pages 64-73 doi: 10.1007/s11708-021-0732-5

Abstract: More flexibility is desirable with the proliferation of variable renewable resources for balancing supply

Keywords: thermostatically controlled load     demand response     renewable energy     power system operation    

is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 942-942 doi: 10.1007/s11684-021-0876-z

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 72-80 doi: 10.15302/J-FASE-2016089

Abstract: Overexpression of miR-148b promoted proliferation of both HHDPC and HHGMC.indicate that miR-148b could activate the Wnt/β-catenin signal pathway by targeting to promote the proliferation

Keywords: miR-148b     hair follicle     proliferation     NFAT5     Wnt10b    

Sub-cytotoxic concentrations of ionic silver promote the proliferation of human keratinocytes by inducing

Xiaodong Duan, Daizhi Peng, Yilan Zhang, Yalan Huang, Xiao Liu, Ruifu Li, Xin Zhou, Jing Liu

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 289-300 doi: 10.1007/s11684-017-0550-7

Abstract: This study investigated the effects of silver ions (Ag+) on the proliferation of human skintreating HaCaT cells with Ag+and/or the active oxygen scavenger N-acetyl cysteine (NAC), cell proliferationThe proliferation of HaCaT cells was promoted in the presence of 106 , with 105 mol/L Ag+ markedly increasing the cell proliferationOur results suggest that sub-cytotoxic Ag+ concentrations promote the proliferation of

Keywords: ionic silver     human keratinocyte     cell proliferation     reactive oxygen species     active oxygen scavenger     NAC    

Effect of repeated gonadotropin stimulation on ovarian reserves and proliferation of ovarian surface

Linlin LIANG, Bei XU, Guijin ZHU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 220-226 doi: 10.1007/s11684-009-0037-2

Abstract: and corpus luteum (CL) in the repeated ovarian stimulated group (81.8%) had a significantly higher proliferationThe proliferation rate of the OSE in the single ovarian stimulated group (56.4%) was significantly higher

Keywords: gonadotropin-releasing hormone     ovarian reserve     embryo developmental ability     ovarian surface epithelium    

Effect of arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the

ZHAN Rong, YU Qinghong, HUANG Haobo

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 356-360 doi: 10.1007/s11684-008-0068-0

Abstract: The aim of this article is to explore the effect of arsenic trioxide (AsO) on the proliferation and apoptosisSo we draw the conclusion that AsO could induce the apoptosis of U266 cells and inhibit their proliferation

Keywords: VEGF expression     expression variation     culture supernatant     labeling     concentration    

Zfyve16 regulates the proliferation of B-lymphoid cells

Xuemei Zhao, Donghe Li, Qingsong Qiu, Bo Jiao, Ruihong Zhang, Ping Liu, Ruibao Ren

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 559-565 doi: 10.1007/s11684-017-0562-3

Abstract: Unpredictably, B cell proliferation is inhibited in Zfyve16KO mice.The proliferation potential of Zfyve16KO B-lymphoid cells also significantlyThese results suggest that Zfyve16 inhibits the proliferation of T cells, possibly through the TGF-βsignaling, but upregulates the proliferation of B-lymphoid cells.

Keywords: Zfyve16     endofin     hematopoiesis     TGF-β     lymphocytes    

Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 784-798 doi: 10.1007/s11684-021-0911-0

Abstract: interference approaches revealed that the loss of GNAQ/11 palmitoylation substantially affected tumor cell proliferationwhich are much more dependent on Gαq/11 signaling for cell survival and proliferation

Keywords: uveal melanoma     mutant GNAQ/11     palmitoylation     BCL2     combination target therapy    

Effect on proliferation and apoptosis of T24 cell lines via silencing DNMT1 with RNA interference

ZHANG Shilong, ZENG Fuqing, PENG Shibo, WANG Liang

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 374-379 doi: 10.1007/s11684-008-0072-4

Abstract: Proliferation and apoptosis were assayed by MTT and flow cytometry with Annexin-V-FITC/PI staining.expression of gene DNMT1 mRNA and protein effectively, and to some extent, it also can inhibit the proliferation

Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts

Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 379-383 doi: 10.1007/s11684-009-0073-y

Abstract: The aim of this study was to investigate if PRAK had effect on cell proliferation.Taken together, gene knockout in MEF cells leads to cell cycle arrest and proliferation inhibition.

Keywords: p38 regulated/activated protein kinase     gene knockout     cell cycle     cell proliferation    

Long non-coding RNA SAP30-2:1 is downregulated in congenital heart disease and regulates cell proliferation

Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 91-100 doi: 10.1007/s11684-020-0778-5

Abstract: Knockdown of lncRNA SAP30-2:1 inhibited the proliferation of human embryonic kidney and AC16 cells andthese results suggest that lncRNA SAP30-2:1 may be involved in heart development through affecting cell proliferation

Keywords: congenital heart disease     Gene Expression Omnibus     lncRNA SAP30-2:1     cell proliferation     RNA immunoprecipitation    

NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 646-657 doi: 10.1007/s11684-018-0643-y

Abstract: Our previous study found that overexpression of gene in PC3 cell line could slow down the tumor proliferationResults of and tumor proliferation experiments and F-fluorothymidine ( F-FLT) micro-positron emission

Keywords: prostate cancer     normal epithelial cell-specific 1/kallikrein 10     sodium/iodide symporter     radiation therapy     proliferation    

Title Author Date Type Operation

Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Journal Article

is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation

Lan Wang,Jueheng Wu,Jie Yuan,Xun Zhu,Hongmei Wu,Mengfeng Li

Journal Article

The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis

Patrick A. Carroll, Brian W. Freie, Haritha Mathsyaraja, Robert N. Eisenman

Journal Article

Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

Journal Article

is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation

Journal Article

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Journal Article

Sub-cytotoxic concentrations of ionic silver promote the proliferation of human keratinocytes by inducing

Xiaodong Duan, Daizhi Peng, Yilan Zhang, Yalan Huang, Xiao Liu, Ruifu Li, Xin Zhou, Jing Liu

Journal Article

Effect of repeated gonadotropin stimulation on ovarian reserves and proliferation of ovarian surface

Linlin LIANG, Bei XU, Guijin ZHU

Journal Article

Effect of arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the

ZHAN Rong, YU Qinghong, HUANG Haobo

Journal Article

Zfyve16 regulates the proliferation of B-lymphoid cells

Xuemei Zhao, Donghe Li, Qingsong Qiu, Bo Jiao, Ruihong Zhang, Ping Liu, Ruibao Ren

Journal Article

Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal

Journal Article

Effect on proliferation and apoptosis of T24 cell lines via silencing DNMT1 with RNA interference

ZHANG Shilong, ZENG Fuqing, PENG Shibo, WANG Liang

Journal Article

Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts

Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,

Journal Article

Long non-coding RNA SAP30-2:1 is downregulated in congenital heart disease and regulates cell proliferation

Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang

Journal Article

NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Journal Article