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Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: dhfr) and dihydropteroate synthetase (dhps) genes of Plasmodium vivax and antifolate resistance-associatedgenes were used for drug resistance surveillance.This study indicated that the antifolate resistance levels of P. vivax parasites were differentacross China and molecular markers could be used to rapidly monitor drug resistance.

Keywords: drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

Metagenomic analysis on resistance genes in water and microplastics from a mariculture system

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 1,   Pages 4-4 doi: 10.1007/s11783-021-1438-y

Abstract: Mariculture systems have been observed to host microplastics and antibiotic resistance genes (ARGs).However, more information on proliferation of ARGs and metal resistance genes (MRGs) in mariculture system

Keywords: Antibiotic resistance genes     Metal resistance genes     Metagenomic analysis     Microplastics     Mariculture    

Fire resistance evaluation through synthetic fire tests and generative adversarial networks

Frontiers of Structural and Civil Engineering 2024, Volume 18, Issue 4,   Pages 587-614 doi: 10.1007/s11709-024-1052-8

Abstract: and time-consuming fire experiments by enlarging small fire test data sets and predicting the fire resistanceWe then use these models to generate synthetic tabular samples that closely resemble realistic fire resistanceMachine, Kernel Support Vector Machine, Naive Bayes, and K-Nearest Neighbors, which can predict the fire resistanceMachine learning analyses achieved highly accurate predictions of fire resistance values, outperformingrevolutionize the field of structural engineering by improving the accuracy and efficiency of fire resistance

Keywords: deep learning     fire resistance     generative adversarial networks     machine learning    

Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea

Frontiers of Environmental Science & Engineering doi: 10.1007/s11783-024-1868-4

Abstract:

● The highest absolute abundance of ARGs in seawater reached 2.3 × 104 copies/mL.

Keywords: The South China Sea     Antibiotic resistance genes     Mobile genetic element     Source apportionment    

Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 701-713 doi: 10.1007/s11684-022-0951-0

Abstract: A significant clinical challenge in lung cancer treatment is management of the inevitable acquired resistanceEvasion of apoptosis is considered a key hallmark of cancer and acquisition of apoptosis resistance isaccordingly a key mechanism of drug acquired resistance in cancer therapy.to apoptosis is tightly associated with the emergence of acquired resistance.undergo apoptosis using various means promises an effective strategy for the management of acquired resistance

Keywords: acquired resistance     EGFR inhibitor     apoptosis     lung cancer    

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 490-495 doi: 10.1007/s11684-018-0647-7

Abstract: While most cancer therapies are given in combinations that are designed to avoid drug resistance, wetherapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drug resistanceThis approach is based on notion that drug resistance comes at a fitness cost to the cancer cell that

Keywords: cancer     drug resistance     genetic screens     senescence     targeted therapy    

Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination

Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1124-5

Abstract:

Extracellular DNA structure damaged by chlorination was characterized.

Integrity of extracellular ARG genetic information after chlorination was determined.

Typical chlorine doses will likely effectively diminish extracellular DNA and ARGs.

Plasmid DNA/ARGs were less readily broken down than genomic DNA.

The Bioanalyzer methodology effectively documented damage incurred to DNA.

Keywords: Antibiotic resistance     Antibiotic resistance genes (ARGs)     Extracellular DNA/ARGs     Chlorination    

Insulin resistance and the metabolism of branched-chain amino acids

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 53-59 doi: 10.1007/s11684-013-0255-5

Abstract:

Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently causes

Keywords: branched-chain amino acids     leucine     isoleucine     valine     insulin resistance    

swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1342-x

Abstract:

• SMX addition had negative effect on acetoclastic methanogens in mesophilic AD.

Keywords: Pig manure     Antibiotics     Anaerobic digestion     Resistance genes     Microbial community    

Transmission of antibiotic resistance genes in agroecosystems: an overview

Jizheng HE, Zhenzhen YAN, Qinglin CHEN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 329-332 doi: 10.15302/J-FASE-2020333

Abstract: antibiotics into the environment, which imposes high selection pressure on bacteria to develop antibiotic resistanceThe spread and aggregation of antibiotic resistance genes (ARGs) in multidrug-resistant pathogens isThe future need to control and mitigate the spread of antibiotic resistance in agricultural ecosystems

Keywords: agroecosystem     antibiotic resistance     public health     soil-plant system    

Characteristics of two transferable aminoglycoside resistance plasmids in

Chengjun Pu, Xiaoyan Gong, Ying Sun

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1119-2

Abstract:

pRKZ3 is a non-conjugative IncQ plasmid, while pKANJ7 is a conjugative IncX plasmid.

The optimal mating time of pKANJ7 varied under different conditions.

Both of the two transferable ARPs had little impact on the growth of their hosts.

A relatively high level of fitness cost was observed for pKANJ7.

The fitness cost of ARPs depended on their hosts.

Keywords: Escherichia coli     Characteristics     Aminoglycoside resistance plasmids     Transfer     Persistence    

Response of antibiotic and heavy metal resistance genes to the co-occurrence of gadolinium and sulfamethoxazole

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 12, doi: 10.1007/s11783-023-1754-5

Abstract:

● Co-occurrence of SMX and Gd(III) enhances HGT of ARGs and MRGs.

Keywords: Antibiotic resistance genes     Heavy metal resistance genes     Mobile genetic elements     Joint effect     Activated    

Distribution and removal of antibiotic resistance genes during anaerobic sludge digestion with alkaline

Mengli Wang, Ruying Li, Qing Zhao

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1127-2

Abstract:

Sludge digestion is critical to control the spread of ARGs from wastewater to soil.

Fate of ARGs in three pretreatment-AD processes was investigated.

UP was more efficient for ARGs removal than AP and THP in pretreatment-AD process.

The total ARGs concentration showed significant correlation with 16S rRNA gene.

The bacteria carrying ARGs could be mainly affiliated with Proteobacteria.

Keywords: Tetracycline resistance genes     Sulfonamide resistance genes     16S rRNA gene     Sludge pretreatment     Anaerobic    

Exploration on electrical resistance tomography in characterizing the slurry spatial distribution in

Frontiers of Structural and Civil Engineering 2024, Volume 18, Issue 3,   Pages 365-379 doi: 10.1007/s11709-024-1049-3

Abstract: This study investigated the application of electrical resistance tomography (ERT) in characterizing the

Keywords: electrical resistance tomography     cemented granular material     grouting     spatial distribution     Archie’    

Analysis of antibiotic resistance of

Yangyang Yu, Xiaolin Zhu, Guanlan Wu, Chengzhi Wang, Xing Yuan

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1123-6

Abstract: p>

There was a seasonal difference in antibiotic resistancelistitem>

The E. coli in the Yitong River was found to have multiple antibiotic resistance

Keywords: Yitong River     Coliform bacteria     Antibiotic resistance     Escherichia coli    

Title Author Date Type Operation

Prevalence of antifolate drug resistance markers in in China

Journal Article

Metagenomic analysis on resistance genes in water and microplastics from a mariculture system

Journal Article

Fire resistance evaluation through synthetic fire tests and generative adversarial networks

Journal Article

Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea

Journal Article

Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Journal Article

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Journal Article

Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination

Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden

Journal Article

Insulin resistance and the metabolism of branched-chain amino acids

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Journal Article

swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance

Journal Article

Transmission of antibiotic resistance genes in agroecosystems: an overview

Jizheng HE, Zhenzhen YAN, Qinglin CHEN

Journal Article

Characteristics of two transferable aminoglycoside resistance plasmids in

Chengjun Pu, Xiaoyan Gong, Ying Sun

Journal Article

Response of antibiotic and heavy metal resistance genes to the co-occurrence of gadolinium and sulfamethoxazole

Journal Article

Distribution and removal of antibiotic resistance genes during anaerobic sludge digestion with alkaline

Mengli Wang, Ruying Li, Qing Zhao

Journal Article

Exploration on electrical resistance tomography in characterizing the slurry spatial distribution in

Journal Article

Analysis of antibiotic resistance of

Yangyang Yu, Xiaolin Zhu, Guanlan Wu, Chengzhi Wang, Xing Yuan

Journal Article