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A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus2 infections

Frontiers of Medicine doi: 10.1007/s11684-023-1011-0

Abstract: and efficacy of nirmatrelvir/ritonavir (Paxlovid) therapy for hemodialysis-dependent patients with severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.Thirteen hemodialysis patients infected with the Omicron variant of SARS-CoV-2 from April 3 to May 30

Keywords： Paxlovid     hemodialysis     SARS-CoV-2     viral load     chest CT scan    

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Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 776-785 doi: 10.1007/s11684-020-0820-7

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread around the world.A total of 13 (13.4%) patients were confirmed positive for SARS-CoV-2 infection by nucleic acid RT-PCR11 confirmed COVID-19 cases, 5 (45.5%) and 7 (63.6%) were positive for IgM and IgG against SARS-CoV-2,A serologic test can be a useful adjunctive diagnostic tool in cases where SARS-CoV-2 infection is highly

Keywords： coronavirus disease 2019     pediatrics     emergency     retrospective investigation     severe acute respiratory syndromecoronavirus 2    

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Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 302-305 doi: 10.1007/s11684-011-0145-7

Abstract: A treatment method based on drainage via retroperitoneal laparoscopy was adopted for 15 severe acute

Keywords： severe acute pancreatitis (SAP)     laparoscope     retroperitoneal drainage     treatment    

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Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 296-301 doi: 10.1007/s11684-012-0219-1

Abstract: improved the development of modern cardiac surgery, many factors during CPB have been reported to induce acuterespiratory distress syndrome (ARDS).results demonstrated that the ratio of arterial oxygen tension/fraction of inspire oxygen (PaO2/FiO2) was greatly reduced in ARDS patients, but only the release of TNF-α wassignificantly increased, which was reversely correlated to the values of PaO2/FiO2

Keywords： tumor necrosis factor-α     cardiopulmonary bypass     inflammation     acute respiratory distress syndrome    

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothersSARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative.SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too.No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 215-218 doi: 10.1007/s11684-007-0041-3

Abstract: From April to June, 2004, an outbreak of acute upper respiratory tract infections (AURTI) occurred inswabs were collected with 13 of them presenting an adenovirus (Ad)-like cytopathogenic effect on HEp-2.By the serologic study, we can definitively diagnose that this outbreak of acute respiratory infections

Keywords： Twenty     Adenovirus     cytopathogenic     type-specific     AURTI    

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High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common RespiratoryAmplification Platform for Rapid Detection of 19 Types of Common Respiratory Viruses Including SARS-CoV-2 Article

Wanli Xing, Yingying Liu, Huili Wang, Shanglin Li, Yongping Lin, Lei Chen, Yan Zhao, Shuang Chao, Xiaolan Huang, Shaolin Ge, Tao Deng, Tian Zhao, Baolian Li, Hanbo Wang, Lei Wang, Yunpeng Song, Ronghua Jin, Jianxing He, Xiuying Zhao, Peng Liu, Weimin Li, Jing Cheng

Engineering 2020, Volume 6, Issue 10,   Pages 1130-1140 doi: 10.1016/j.eng.2020.07.015

Abstract: quot;serif"">Fast and accurate diagnosis and the immediate isolation of patients infected with severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) are regarded as the most effective measures toviruses, including SARS-CoV-2, from 16 samples in a single run within 90 min.test results matched the referenced results well and reflected the epidemic characteristics of the respiratoryrate of the RTisochipTM-W with the referenced kits was 98.15% for the detection of SARS-CoV-2.

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus 2     Microfluidics     Nucleic acid    

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The Scientific Foundation of Chinese Herbal Medicine against COVID-19 Perspective

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Engineering 2020, Volume 6, Issue 10,   Pages 1099-1107 doi: 10.1016/j.eng.2020.08.009

Abstract: Supporting evidence shows that COVID-19 shares a genomic similarity with other coronaviruses, such as severeacute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome  coronaviruspathological features of COVID-19 patients, patients can suffer from five steps of progression, starting with severe

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus     Chinese herbal medicine     Antiviral    

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Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 664-673 doi: 10.1007/s11684-020-0810-9

Abstract: The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 was identified in December 2019.The symptoms include fever, cough, dyspnea, early symptom of sputum, and acute respiratory distress syndromeMesenchymal stem cell (MSC) therapy is the immediate treatment used for patients with severe cases of

Keywords： coronavirus disease 2019 (COVID-19)     mesenchymal stem cell     acute respiratory distress syndrome     stem cell    

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Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 405-409 doi: 10.1007/s11684-016-0476-5

Abstract: destruction for periodontal diseases and other chronic diseases like diabetes mellitus, atherosclerosis, respiratoryOral colonization by respiratory pathogens appears to be a risk factor for development of respiratoryThis reflects the importance of oral hygiene among patients with respiratory illness.This review highlights the association between periodontal diseases and respiratory diseases.

Keywords： periodontitis     respiratory diseases     acute pneumonia     COPD    

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Cross-sectional prevalence and pattern of non-anaemia severe malaria among 2–10 year olds in Sokoto in

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 969-974 doi: 10.1007/s11684-021-0912-z

Abstract: A cross-sectional study was conducted among 2–10-year-old children in Sokoto, in August and December, to determine the endemicity of malaria based on Plasmodium falciparum prevalence rate (PfPR2-Severe malaria was diagnosed according to the World Health Organisation criteria.pattern which was mesoendemic based on a PfPR2-10 of 34.8%.The mean age of children with severe malaria was 3.73 years, and the male–female ratio was 2:1.

Keywords： severe malaria     nigeria     malaria mortality     PfPR2-10     intermediate malaria transmission    

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Temporal and Spatial Distribution of SARS-CoV-2 Aerosols in a Large-Scale Fangcang Shelter Hospital in Article

Jiafu Jiang, Zhe Yin, Jing Li, Leili Jia, Rulin He, Wenhui Yang, Jihu Yang, Hang Fan, Sen Zhang, Yunfei Wang, Zengming Zhao, Haoran Peng, Lizhong Li, Yi Yang, Shi-Yong Fan, Rong Xiang, Jianshu Guo, Jinjin Wang, Juanning Wei, Fengling Zhou, Ding Liu, Ping Zhao, Yujun Cui, Yunxi Liu, Dongsheng Zhou, Gang Dong

Engineering 2023, Volume 28, Issue 9,   Pages 225-236 doi: 10.1016/j.eng.2023.06.006

Abstract:

The coronavirus disease 2019 (COVID-19) pandemic caused by frequently mutating severe acute respiratorysyndrome coronavirus 2 (SARS-CoV-2) has had a worldwide impact.However, detailed data on the potential aerosol transmission of SARS-CoV-2 in real-world and controlledThe positivity rate for SARS-CoV-2 in aerosol samples was high in contaminated zones (37.5%, 104/277)or other respiratory virus diseases in a Fangcang shelter hospital.

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus 2     Aerosols     Fangcang shelter    

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Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 285-288 doi: 10.1007/s11684-018-0626-z

Abstract: Cases of acute pancreatitis induced by organophosphate intoxication are encountered occasionally in clinics, but very few of them develop into severe pancreas necrosis and irreversible pancreatic function impairmentThe patient recovered gradually, was discharged after 2 weeks, and was prescribed with oral pancreatin

Keywords： organophosphate intoxication     severe acute pancreatitis     pancreas necrosis     percutaneous catheterization    

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Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

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Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation blockin acute promyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: Here, we report that cyclin-dependent kinase inhibitor 2C (CDKN2C) as a member of the cyclin-dependentkinase inhibitors is a target of the PML/RARα oncofusion protein in leukemogenesis of acute promyelocyticWe found that CDKN2C was markedly downregulated in APL blasts compared with normal promyelocytes.Functional studies showed that ectopic expression of CDKN2C induced a cell cycle arrest at the GFinally, the transcriptional regulation of CDKN2C was validated in primary APL patient samples.

Keywords： CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

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Title Author Date Type Operation

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus2 infections

Journal Article

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Journal Article

Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Journal Article

Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Journal Article

High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common RespiratoryAmplification Platform for Rapid Detection of 19 Types of Common Respiratory Viruses Including SARS-CoV-2

Wanli Xing, Yingying Liu, Huili Wang, Shanglin Li, Yongping Lin, Lei Chen, Yan Zhao, Shuang Chao, Xiaolan Huang, Shaolin Ge, Tao Deng, Tian Zhao, Baolian Li, Hanbo Wang, Lei Wang, Yunpeng Song, Ronghua Jin, Jianxing He, Xiuying Zhao, Peng Liu, Weimin Li, Jing Cheng

Journal Article

The Scientific Foundation of Chinese Herbal Medicine against COVID-19

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Journal Article

Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Journal Article

Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Journal Article

Cross-sectional prevalence and pattern of non-anaemia severe malaria among 2–10 year olds in Sokoto in

Journal Article

Temporal and Spatial Distribution of SARS-CoV-2 Aerosols in a Large-Scale Fangcang Shelter Hospital in

Jiafu Jiang, Zhe Yin, Jing Li, Leili Jia, Rulin He, Wenhui Yang, Jihu Yang, Hang Fan, Sen Zhang, Yunfei Wang, Zengming Zhao, Haoran Peng, Lizhong Li, Yi Yang, Shi-Yong Fan, Rong Xiang, Jianshu Guo, Jinjin Wang, Juanning Wei, Fengling Zhou, Ding Liu, Ping Zhao, Yujun Cui, Yunxi Liu, Dongsheng Zhou, Gang Dong

Journal Article

Total pancreatic necrosis after organophosphate intoxication

Rui Hou, Hongmin Zhang, Huan Chen, Yuankai Zhou, Yun Long, Dawei Liu

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation blockin acute promyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article