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Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging

Liangqian Tong, Ming Zhao, Shu Zhu, Jing Chen

Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 379-387 doi: 10.1007/s11684-011-0162-6

Abstract: Superparamagnetic iron oxide (SPIO) nanoparticles have become a popular strategy of cancer treatment

Keywords： nanoparticles superparamagnetic iron oxide targeted therapy molecular imaging cancer

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Preparation and property characterization of PAA/Fe3O4 nanocomposite

WEI Shanshan, ZHANG Yi, XU Jiarui

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 3, Pages 233-237 doi: 10.1007/s11705-007-0042-4

Abstract: The nanocomposites showed superparamagnetic properties at 300 K.

Keywords： magnetometer superparamagnetic ultra-micro thermogravimetry transmission

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(Super)paramagnetic nanoparticles as platform materials for environmental applications: From synthesis to demonstration

Wenlu Li, John D. Fortner

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1256-7

Abstract: • The fabrication of monodisperse, (super)paramagnetic nanoparticles is summarized. • Monolayer and bilayer surface coating structures are described. • Mono/bilayer coated nanoparticles showed high sorption capacities for U, As, and Cr. Over the past few decades, engineered, (super)paramagnetic nanoparticles have drawn extensive research attention for a broad range of applications based on their tunable size and shape, surface chemistries, and magnetic properties. This review summaries our recent work on the synthesis, surface modification, and environmental application of (super)paramagnetic nanoparticles. By utilizing high-temperature thermo-decomposition methods, first, we have broadly demonstrated the synthesis of highly monodispersed, (super)paramagnetic nanoparticles, via the pyrolysis of metal carboxylate salts in an organic phase. Highly uniform magnetic nanoparticles with various size, composition, and shape can be precisely tuned by controlled reaction parameters, such as the initial precursors, heating rate, final reaction temperature, reaction time, and the additives. These materials can be further rendered water stable via functionalization with surface mono/bi-layer coating structure using a series of tunable ionic/non-ionic surfactants. Finally, we have demonstrated platform potential of these materials for heavy metal ions sensing, sorption, and separation from the aqueous phase.

Keywords： Superparamagnetic nanoparticles Surface functionalization Environmental sensing Heavy metal ion sorption