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Whole-life Thinking and Engineering the Future

Roger Flanagan

Frontiers of Engineering Management 2014, Volume 1, Issue 3, Pages 290-296 doi: 10.15302/J-FEM-2014040

Abstract: Whole-life thinking for engineers working on the built environment has become more important in a fastWhole-life thinking is not new, every project attempts to balance the initial capital cost with the operatingSystems thinking provides one approach to developing a more robust whole-life approach.New approaches are needed to produce more reliable whole-life predictions.Best value, rather than lowest cost, can be achieved by using whole-life appraisal as a part of the design

Keywords： whole-life thinking systems thinking complexity chaos risk management through life

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General framework for bridge life cycle design

Junhai MA, Airong CHEN, Jun HE

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 1, Pages 50-56 doi: 10.1007/s11709-009-0004-7

Abstract: Based on a detailed illustration for bridge life cycle design which comprises the processes of servicelife design, aesthetics design, performance design, environmental and ecological design, inspection,maintenance and repair design as well as cost analysis, this paper presented a general framework for bridge life

Keywords： bridge whole life design design phase design process general framework

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The Research on Subject Behavioral Risk of Whole Life-cycle Water Conservation Projects

Hong-yong Liu,Ji Guo,Wei-tao He

Frontiers of Engineering Management 2014, Volume 1, Issue 4, Pages 348-352 doi: 10.15302/J-FEM-2014048

Abstract: This article takes each participating subject in the whole life-cycle of water conservation projects

Keywords： water conservation projects subject behavior safety accident risk effect engineering ethics

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Sustainable development oriented design theory ofengineering structures in whole life cycle

Jin Weiliang and Zhong Xiaoping

Strategic Study of CAE 2012, Volume 14, Issue 3, Pages 100-107

Abstract: text-align: justify;">In this study, a durability design theory system for engineering structures' wholelife-cycle design is established.in the whole life time domain.The performance index, economic index and service life index are considered as key indexes in the wholeproposed new durability design theory system could be used in structural performance optimization in whole

Keywords： sustainable development-oriented design theory structural whole life structural reliability structurallifecycle cost structural service life

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On Creativity Thinking

Feng Guorui

Strategic Study of CAE 2004, Volume 6, Issue 6, Pages 15-21

Abstract: stress on discussion of the definition, the evolution mechamism and the great significance of creativity thinkingas well as the problems of raising overall synthetical diathesis of the thinking subject.

Keywords： innovation creation creativity thinking thinking subject thinking object

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Qian Xuesen—An Example for Scientific and Technological Circles to Learn From

Tu Yuanji

Strategic Study of CAE 2002, Volume 4, Issue 2, Pages 1-7

Abstract:

Qian Xuesen´s life-time is reviewed in this article and his excellent character and behaviour

Keywords： life-time seek knowledge tackle key problems in science and technology work style thinking and moral

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Organizational evolution of project management teams over the whole lifecycle of megaprojects: Case study

Frontiers of Engineering Management Pages 439-454 doi: 10.1007/s42524-022-0211-7

Abstract: Project management teams are critical in the implementation of megaprojects, but their evolution throughout the project lifecycle has not been clearly explained. This paper explores the organizational evolution of megaproject management teams through a longitudinal retrospective case study of the Hong Kong–Zhuhai–Macao Bridge (HZMB) project. The organizational evolution is examined in terms of management objectives, management content, and organizational structure. The organizational evolution of the HZMB project management team exhibits stage differentiation with the coexistence of turbulence and stability. Changes in the external environment are the driving force for organizational evolution, whereas a flexible organizational strategy is critical in promoting this evolution. Basing on the HZMB case study, this paper summarizes six critical measures that facilitate the organizational evolution of megaproject management teams. Our findings add value to megaproject management theory and provide a better understanding of the dynamics and complexity of megaproject organizational management.

Keywords： megaproject organizational evolution whole lifecycle management project management team

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TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways

Daniel Wai-Hung Ho,Alan Ka-Lun Kai,Irene Oi-Lin Ng

Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 322-330 doi: 10.1007/s11684-015-0408-9

Abstract:

This study systematically evaluates the TCGA whole-transcriptome sequencing data of hepatocellular

Keywords： TCGA whole-transcriptome sequencing HCC liver cancer

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Strategic Thinking on Shallow-water Oil and Gas Exploration in Offshore China

Ke-qiang Wu,Jian-yong Xu,Bo Kang

Frontiers of Engineering Management 2016, Volume 3, Issue 4, Pages 349-355 doi: 10.15302/J-FEM-2016056

Abstract: The oil and gas exploration in offshore China has made great achievements, and as the important areas of offshore exploration, the shallow waters contribute most of the oil and gas reserves and production. However, the available area for exploration is diminishing and the cost of exploration is rising. The field changes and ever increasing difficulties of exploration bring new challenges technically and economically. Therefore, for effective exploration of shallow-water oil and gas in offshore China, it is necessary to center on the general requirements of becoming a powerful marine country and the ideas of value exploration, initiate key research projects in the fields of China’s offshore stratigraphic-lithologic reserves, Paleogene reserves, buried-hill reserves, high temperature and pressure reserves and hydrocarbon-rich sags, and form geological theories and explorative technologies of large and medium size oil and gas field in offshore China. The measures regarding the challenges include: (1) Innovating theoretical understanding and optimizing new exploration fields, (2) developing technical capabilities and improving the success rate of exploration, and (3) enhancing management level and deepening value exploration.

Keywords： offshore China shallow-water oil and gas exploration strategic thinking challenge countermeasure

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Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing

Frontiers of Medicine doi: 10.1007/s11684-023-0994-x

Abstract: Whole-genome sequencing was performed on 68 newly diagnosed Chinese PCNSL samples, whose genomic characteristics

Keywords： primary central nervous system lymphoma whole-genome sequencing TMSB4X copy number variation

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Cell surface protein engineering for high-performance whole-cell catalysts

Hajime Nakatani,Katsutoshi Hori

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1, Pages 46-57 doi: 10.1007/s11705-017-1609-3

Abstract: surface proteins using genetic engineering, and is important for the development of high-performance whole-celldiscuss advanced methods for displaying multiple enzymes and a new method for the immobilization of whole-cell

Keywords： cell surface engineering surface display whole-cell catalysts bioprocess

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Calling systematic thinking in addressing water security issues

Jining CHEN, Pengfei DU

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 5, Pages 625-625 doi: 10.1007/s11783-013-0564-6

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Efficient acetoin production from pyruvate by engineered whole-cell biocatalysis

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4, Pages 425-436 doi: 10.1007/s11705-022-2229-0

Abstract: Moreover, the reusability of the cell catalysis was also tested, and the result illustrated that the whole-cellThis work therefore provided an efficient H. bluephagenesis whole-cell catalysis with a broad

Keywords： -acetolactate synthetase α-acetolactate decarboxylase Halomonas bluephagenesis whole-cell

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From systematicness to complexity: Fundamental thinking of mega-project management

Zhaohan SHENG, Han LIN

Frontiers of Engineering Management 2018, Volume 5, Issue 1, Pages 125-127 doi: 10.15302/J-FEM-2018001

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Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the

Biao Kan, Haijian Zhou, Pengcheng Du, Wen Zhang, Xin Lu, Tian Qin, Jianguo Xu

Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 23-33 doi: 10.1007/s11684-017-0607-7

Abstract:

Two decades have passed since the first bacterial whole-genome sequencing, which provides new opportunityBacterial whole-genome sequencing and bioinformatic computing allow genotyping to satisfy the requirements

Keywords： genome sequencing genomic epidemiology bacteria surveillance infectious diseases