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General modeling and optimization technique for real-world earth observation satellite scheduling

Frontiers of Engineering Management 2023, Volume 10, Issue 4,   Pages 695-709 doi: 10.1007/s42524-023-0263-3

Abstract: observation satellite (EOS) scheduling problems, but few of them show good generality to be engineered in real-worldThis study proposes a general modeling and optimization technique for common and real-world EOS schedulingIn addition, a complicatedly constrained real-world benchmark exampled by a four-EOS Chinese commercial

Keywords： observation satellite     scheduling     general technique     optimization algorithm     commercial constellation     real-world    

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Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 310-315 doi: 10.1007/s11684-014-0358-7

Abstract: discusses the integration of science, technology, and medicine under the guidance of the paradigm of real-worldThus, these methods strongly support the real-world clinical research paradigm of TCM.

Keywords： big data     real world     clinical research     Chinese medicine     medical computing    

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Quantification of emission variability for off-road equipment in China based on real-world measurements

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 2, doi: 10.1007/s11783-021-1455-x

Abstract:

• Emissions from 53 in-use diesel-fueled off-road equipment were measured.

Keywords： Off-road equipment     Portable emission measurement system (PEMS)     Real-world emissions     Diesel engine    

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Discussion of solutions to ethical issues in real-world study

Sicheng Wang,Baoyan Liu,Ningning Xiong,Qi Xie,Runshun Zhang,Xuezhong Zhou,Jie Qiao

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 316-320 doi: 10.1007/s11684-014-0354-y

Abstract:

In recent years, the paradigm of real-world study (RWS) has been at the forefront of clinical researchIn this paper, basic features and nature of real-world clinical studies are discussed, and ethical issues

Keywords： real-world study     ethics     strategy    

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Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 382-388 doi: 10.1007/s11684-014-0368-5

Abstract: With a view of developing a “real-world traditional Chinese medicine clinical research paradigm

Keywords： clinical research     shared system     real world     research outpatient clinic     research hospital    

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Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 300-309 doi: 10.1007/s11684-014-0357-8

Abstract: era as well as the formation and practice accumulation of the TCM clinical research paradigm in the realworld have provided new perspectives, techniques, and methods for inheriting experience from famouscontinuous exploration and practice, the research group proposes the innovation research mode based on the real-world

Keywords： traditional Chinese medicine (TCM)     real world     clinical research paradigm     famous specialist     experience    

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Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris

Yufeng Zhao, Xueyun Yu, Xinyu Cao, Lin Luo, Liyun He, Shusong Mao, Li Ma, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 566-571 doi: 10.1007/s11684-017-0556-1

Abstract:

Syndromes of coronary heart disease with angina pectoris were analyzed to provide guidance for clinical practice and to improve accuracy of traditional Chinese medicine (TCM) diagnoses and efficacy of TCM treatment. A total of 860 cases with coronary heart disease with angina pectoris were selected from TCM Clinical Research Information Sharing System for TCM clinics and research. Syndromes were automatically extracted with the cluster method and were analyzed to provide objective evidence for clinical studies. Final syndrome classifications were recognized and confirmed by clinical experts. Popular syndromes included Qi and blood deficiency, blood stasis and obstruction collaterals, liver depression and spleen deficiency, and Qi stagnation and blood stasis. Syndromes Qi and blood deficiency and blood stasis and obstruction collaterals accounted for 28.61% of total syndromes, whereas liver depression and spleen deficiency and Qi stagnation and blood stasis accounted for 26.44%. The main syndrome elements comprised Qi deficiency, blood deficiency, blood stasis, and Qi stagnation.

Keywords： syndrome differentiation     real-world study     coronary heart disease with angina pectoris     cluster analysis    

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Real-world effectiveness and safety of Janus kinase 1 inhibitors for the treatment of moderate-to-severe

Frontiers of Medicine 2024, Volume 18, Issue 4,   Pages 752-756 doi: 10.1007/s11684-024-1063-9

Abstract: Real-world effectiveness and safety of Janus kinase 1 inhibitors for the treatment of moderate-to-severe

Keywords： study China     world effectiveness safety    

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” treatment plan for reducing mortality of patients with hepatitis B-related liver failure based on real-world

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: On the basis of real-world clinical data, the study aimed to explore the effect and mechanisms of the

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration microenvironment     cytokines    

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Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective cohort study

Frontiers of Medicine 2023, Volume 17, Issue 5,   Pages 867-877 doi: 10.1007/s11684-023-0995-9

Abstract: Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of inactivated vaccines is not well characterized in people with comorbidities, who are at high risk of severe infection. We compared the risk of SARS-CoV-2 infection after complete vaccination with Sinopharm/BBIBP in people with comorbidities (e.g., autoimmune diseases, cardiovascular disease, chronic lung disease, and diabetes) with healthy individuals using a Cox-proportional hazard model. In July–September 2021, a total of 10 548 people (comorbidities, 2143; healthy, 8405) receiving the complete primary series of vaccination with Sinopharm/BBIBP in Bangkok, Thailand were prospectively followed for SARS-CoV-2 infection through text messaging and telephone interviewing for 6 months. A total of 295 infections from 284 participants were found. HRs (95% CI) of individuals with any comorbidities did not increase (unadjusted, 1.02 (0.77–1.36), P = 0.89; adjusted, 1.04 (0.78–1.38), P = 0.81). HRs significantly increased in the subgroup of autoimmune diseases (unadjusted, 2.64 (1.09–6.38), P = 0.032; adjusted, 4.45 (1.83–10.83), P = 0.001) but not in cardiovascular disease, chronic lung disease, or diabetes. The protection against SARS-CoV-2 infection of the Sinopharm vaccine was similar in participants with any comorbidities vs. healthy individuals. However, the protection appeared lower in the subgroup of autoimmune diseases, which may reflect suboptimal immune responses among these people.

Keywords： COVID-19     Sinopharm/BBIBP vaccine     immunocompromised patients     real-world    

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Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1212-6

Abstract: . • The discrepancy between the approved FC and real-world FC is 13%±18%. • There is a strong relationshipAn increasing discrepancy between real-world and type-approval fuel consumption for light-duty passengerNormally, real-world fuel consumption is measured primarily by a portable emission measurement systemFurthermore, the real-world fuel consumption of six LDPVs was tested in Beijing using the OBD.The results showed that the normalized NEDC real-world fuel consumption of the tested vehicles was 13%

Keywords： Fuel consumption     Light-duty passenger vehicles     On-board diagnostic systems    

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Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 352-357 doi: 10.1007/s11684-014-0351-1

Abstract:

Real world study (RWS) has become a hotspot for clinical research.

Keywords： real world study     traditional Chinese medicine     clinical and research information sharing system     data quality    

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Block coordinate descent with time perturbation for nonconvex nonsmooth problems in real-world studies Research Article

Rui Liu, Wei-chu Sun, Tao Hou, Chun-hong Hu, Lin-bo Qiao,liuruirui@csu.edu.cn,smsysun@foxmail.com,houtao@csu.edu.cn,huchunhong@csu.edu.cn,qiao.linbo@nudt.edu.cn

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 10,   Pages 1390-1403 doi: 10.1631/FITEE.1900341

Abstract: However, traditional machine learning algorithms need to be promoted to solve such large-scale real-worldExperiments conducted on real-world machine learning problems validate the efficacy of our proposed method

Keywords： 收敛分析；异步块坐标下降法；时间扰动；非凸非平滑优化；真实世界研究    

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Thinking and practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based medicine

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 163-170 doi: 10.1007/s11684-011-0143-9

Abstract: idea of “taking two ways simultaneously,” which is the study both in the ideal condition and in the realworld.Analyzing and constructing the theoretical basis and methodology of clinical research in the real worldOnly by gradually maturing and completing the clinical research methods of the real world could we realize

Keywords： Chinese medicine     experience medicine     evidence-based medicine     real world    

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Collaborations of China with the world in Synbio

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 1-2 doi: 10.1007/s11705-017-1638-y

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Title Author Date Type Operation

General modeling and optimization technique for real-world earth observation satellite scheduling

Journal Article

Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Journal Article

Quantification of emission variability for off-road equipment in China based on real-world measurements

Journal Article

Discussion of solutions to ethical issues in real-world study

Sicheng Wang,Baoyan Liu,Ningning Xiong,Qi Xie,Runshun Zhang,Xuezhong Zhou,Jie Qiao

Journal Article

Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Journal Article

Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Journal Article

Cluster analysis for syndromes of real-world coronary heart disease with angina pectoris

Yufeng Zhao, Xueyun Yu, Xinyu Cao, Lin Luo, Liyun He, Shusong Mao, Li Ma, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Journal Article

Real-world effectiveness and safety of Janus kinase 1 inhibitors for the treatment of moderate-to-severe

Journal Article

” treatment plan for reducing mortality of patients with hepatitis B-related liver failure based on real-world

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective cohort study

Journal Article

Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

Journal Article

Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Journal Article

Block coordinate descent with time perturbation for nonconvex nonsmooth problems in real-world studies

Rui Liu, Wei-chu Sun, Tao Hou, Chun-hong Hu, Lin-bo Qiao,liuruirui@csu.edu.cn,smsysun@foxmail.com,houtao@csu.edu.cn,huchunhong@csu.edu.cn,qiao.linbo@nudt.edu.cn

Journal Article

Thinking and practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based medicine

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

Journal Article

Collaborations of China with the world in Synbio

Journal Article