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<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 81-86 doi: 10.15302/J-FASE-2016088

Abstract: virulence-determining genes, and encode the small subunit and large subunit of viral ribonucleotide reductase (RR

Keywords： pseudorabies virus     <i>RR1i> and <i>RR2i>     ribonucleotide reductase     vaccine candidate    

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Deciphering the Origins of P1-Induced Power Losses in Cu(In<i>xi>,Ga1–<i>xi>)Se2 (CIGS) Modules Through Hyperspectral Luminescence Article

César Omar Ramírez Quiroz, Laura-Isabelle Dion-Bertrand, Christoph J. Brabec, Joachim Müller, Kay Orgassa

Engineering 2020, Volume 6, Issue 12,   Pages 1395-1402 doi: 10.1016/j.eng.2019.12.019

Abstract: hyperspectral high-resolution photoluminescence mapping is a powerful tool for the selection and optimiz1ationprocesses used for the patterning interconnections of subcells on Cu(Inx,Ga1-x)Se2 (CIGS) modules.We further rationalize the origins of this effect by comparing the topography of the P1 edge throughWe also investigate the laser-induced damage on P1 patterning lines performed after the deposition of

Keywords： Cu(Inx     Ga1-x)Se2     Cell-to-module efficiency gap     P1-induced power losses     Hyperspectral photoluminescence    

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Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 76-84 doi: 10.1007/s11684-015-0426-7

Abstract:

Anti-β2 glycoprotein I (anti-β2GP I ) antibodies are importantba (GP I bα) in platelet activation induced by the anti-β2GP I /β22GP I /β2GP I complex and plateletsOur results revealed that the anti-β2GP I /β2GP I complex was able toResults showed that the anti-β2GP I /β2GP I complex induced platelet

Keywords： anti-β2GP I /β2GP I complex     platelet     GP I bα     apoER2'     thrombosis    

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<i>NES1i>/<i>KLK10i> and <i>hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 646-657 doi: 10.1007/s11684-018-0643-y

Abstract: , we supposed to have an “enhanced firepower” effect by combining overexpressed gene therapy and Itomography/computed tomography (micro-PET/CT) imaging showed that the combined gene therapy and Ithat via inhibition of expression, overexpressed might enhance the effect of radiation therapy of I

Keywords： androgen-independent prostate cancer     normal epithelial cell-specific 1/kallikrein 10     sodium/iodide symporter    

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Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 808-814 doi: 10.1007/s11684-021-0878-x

Abstract: Chinese families with EB, and eight variants including a novel nonsense variant (c.47G>A, p.W16*) in <i>LAMA3i>, a known recurrent variant (c.74C>T, p.P25L) in <i>KRT5i>, 2 novel (c.2531T>A, p.V844E; cCOL7A1 i>were detected.Notably, this study identified a nonsense variant in <i>LAMA3i> that causes EB within the Chinese populationand revealed that this variant resulted in a reduction in <i>LAMA3i> mRNA and protein expression levels

Keywords： epidermolysis bullosa     <i>LAMA3i>     <i>COL7A1i>     <i>KRT5i>     Chinese families    

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Identification of genome regions and important variations associated with expression level of

Ye HOU,Lu JING,Yunxia ZHAO,Sheng WANG,An LIU,Shuhong ZHAO,Xinyun LI

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3,   Pages 237-241 doi: 10.15302/J-FASE-2015057

Abstract: muscle fibers contain three isoforms, IIa, IIb and IIx, which contain specific myofibrillar proteins MYH2,MYH4 and MYH1, respectively.

Keywords： pig     IMF     pH     <i>MYH1i>     <i>MYH2i>     <i>MYH4i>    

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SARS-CoV-2 Entry Factors: <i>ACE2i> and <i>TMPRSS2i> Are Expressed in Peri-Implantation Embryos and Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world, leadingAngiotensin-converting enzyme 2 (ACE2) is the receptor of both severe acute respiratory syndrome coronavirus(SARS-CoV) and SARS-CoV-2.In order to investigate the potential risk of SARS-CoV-2 vertical transmission, we explored ACE2/em> and TMPRSS2, indicating SARS-CoV-2 infection susceptibility.

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract:

Podoplanin (PDPN) is a mucin-type <i>Oi>-glycoprotein expressed in diverse cell types, suchPDPN on LECs or FRCs activates CLEC-2 in platelets, triggering platelet activation and/or aggregationvascular system, normal expression of PDPN at the LEC surface requires transcriptional activation of <i>Pdpni> by Prox1 and modification of PDPN with core 1-derived <i>Oi>-glycans.

Keywords： podoplanin     CLEC-2     Prox1     <i>Oi>-glycosylation     lymphatic vascular development and maintenance     lymphoid    

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Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressiveFAT1 and inhibits stemness maintenance in thyroid carcinoma

Frontiers of Medicine doi: 10.1007/s11684-023-0999-5

Abstract: Through bioinformatics predictions, we identified that GTF2I and FAT1 were downregulated in thyroid carcinomaThe under-expression of GTF2I and FAT1 was validated in TC cell lines.Ectopically expressed GTF2I and FAT1 were found to augment malignant phenotypes of TC cells, EMT, andMechanistic studies revealed that GTF2I bound to the promoter region of FAT1 and consequently upregulatedMSC-EVs could shuttle GTF2I into TPC-1 cells, where GTF2I inhibited TC malignant phenotypes, EMT, and

Keywords： thyroid carcinoma     mesenchymal stem cell     extracellular vesicle     GTF2I     FAT1     CDK4    

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<i>Ni>-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probesfor <i>in vivoi> cell H2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 64-71 doi: 10.1007/s11705-021-2048-8

Abstract: Heterocyclic compound quinoline and its derivatives exist in natural compounds and have a broad spectrum of biological activity. They play an important role in the design of new structural entities for medical applications. Similarly, indoles and their derivatives are found widely in nature. Amino acids, alkaloids and auxin are all derivatives of indoles, as are dyes, and their condensation with aldehydes makes it easy to construct reaction sites for nucleophilic addition agents. In this work, we combine these two groups organically to construct a rapid response site (within 30 s) for H S, and at the same time, a ratiometric fluorescence response is presented throughout the process of H S detection. As such, the lower detection limit can reach 55.7 nmol/L for H S. In addition, cell imaging shows that this probe can be used for the mitochondrial targeted detection of endogenous and exogenous H S. Finally, this probe application was verified by imaging H S in nude mice.

Keywords： heterocyclic compound     hydrogen sulfide     ratiometric     mitochondrial targeted    

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Evaluation of H2 on the Evolution Mechanism of NO<i>xi> Storage and Reductionover Pt–Ba–Ce/γ-Al2O3 Catalysts Article

Pan Wang, Jing Yi, Chuan Sun, Peng Luo, Lili Lei

Engineering 2019, Volume 5, Issue 3,   Pages 568-575 doi: 10.1016/j.eng.2019.02.005

Abstract:

In this investigation, Pt–Ba–Ce/γ-Al2O3 catalysts were preparedby incipient wetness impregnation and experiments were performed to evaluate the influence of H2 ontemperature range of 250–350 °C, and reached a maximum value of 315.3 μmol·g−1cat at 350 °C, which was ascribed to the increase in NO2 yield./sub> exposure (i.e., 30 s, 45 s, and 60 s) was extended.

Keywords： Pt–Ba–Ce/γ-Al2O3 catalysts     Physicochemical properties     NO<i>xi> storageand reduction     NO<i>xi> emission     H2 reductant    

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Band-gap tunable (Ga<i>xi>In1−<i>xi>)2O3 layer Research Articles

Fabi Zhang, Jinyu Sun, Haiou Li, Juan Zhou, Rong Wang, Tangyou Sun, Tao Fu, Gongli Xiao, Qi Li, Xingpeng Liu, Xiuyun Zhang, Daoyou Guo, Xianghu Wang, Zujun Qin,zhangfabi@outlook.com,qinzj@guet.edu.cn

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 10,   Pages 1370-1378 doi: 10.1631/FITEE.2000330

Abstract: Multicomponent oxide (GaIn)O films are prepared on (0001) sapphire substrates to realize a tunable band-gap by technology followed by thermal annealing. The optical properties and band structure evolution over the whole range of compositions in ternary compounds (GaIn)O are investigated in detail. The X-ray diffraction spectra clearly indicate that (GaIn)O films with Ga content varying from 0.11 to 0.55 have both cubic and monoclinic structures, and that for films with Ga content higher than 0.74, only the monoclinic structure appears. The transmittance of all films is greater than 86% in the visible range with sharp absorption edges and clear fringes. In addition, a blue shift of ultraviolet absorption edges from 380 to 250 nm is noted with increasing Ga content, indicating increasing band-gap energy from 3.61 to 4.64 eV. The experimental results lay a foundation for the application of transparent conductive compound (GaIn)O thin films in photoelectric and photovoltaic industry, especially in display, light-emitting diode, and solar cell applications.

Keywords： (GaxIn1−x)2O3薄膜；带隙可调谐；磁控溅射    

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NO<i>xi> and H2S formation in the reductive zone of air-staged combustion of

Jinzhi CAI, Dan LI, Denggao CHEN, Zhenshan LI

Frontiers in Energy 2021, Volume 15, Issue 1,   Pages 4-13 doi: 10.1007/s11708-020-0804-y

Abstract: Low NO combustion of blended coals is widely used in coal-fired boilers in China to control NO emission; thus, it is necessary to understand the formation mechanism of NO and H S during the combustion of blended coals. This paper focused on the investigation of reductive gases in the formation of NO and H S in the reductive zone of blended coals during combustion. Experiments with Zhundong (ZD) and Commercial (GE) coal and their blends with different mixing ratios were conducted in a drop tube furnace at 1200°C–1400°C with an excessive air ratio of 0.6–1.2. The coal conversion and formation characteristics of CO, H S, and NO in the fuel-rich zone were carefully studied under different experimental conditions for different blend ratios. Blending ZD into GE was found to increase not only the coal conversion but also the concentrations of CO and H S as NO reduction accelerated. Both the CO and H S concentrations inblended coal combustion increase with an increase in the combustion temperature and a decrease in the excessive air ratio. Based on accumulated experimental data, one interesting finding was that NO and H S from blended coal combustion were almost directly dependent on the CO concentration, and the CO concentration of the blended coal combustion depended on the single char gasification conversion.Thus, CO, NO , and H S formation characteristics from blended coal combustion can be well predicted by single char gasification kinetics.

Keywords： blended coal combustion     NO<i>x i>formation     H2S formation     air staged combustion    

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Successful production of an all-female common carp (<i>Cyprinus carpioi> L.) population using <i>cyp17a1i>-deficient neomale carp Article

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Engineering 2022, Volume 8, Issue 1,   Pages 181-189 doi: 10.1016/j.eng.2021.03.026

Abstract: Male and female heterozygous cyp17a1-deficient common carp were first obtained using the clusteredAn all-male phenotype for homozygous cyp17a1-deficient carp, regardless of the individuals&rsquoour laboratory was used to screen the neomale carp population with the XX genotype from the cyp17a1cyp17a1+/+ XX genotype)The average body weight of cyp17a1+/− XX females was higher by 6.60% (8 mpf) and 32.66%

Keywords： Common carp     Sexual dimorphism     Growth     <i>cyp17a1i>     Sex steroids     All-female population    

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Comparison of growth and lipid accumulation properties of two oleaginous microalgae under different nutrient conditions

Qiao ZHANG,Yu HONG

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 703-709 doi: 10.1007/s11783-014-0649-x

Abstract: LX1 and sp. HQ, under different nutrient conditions.LX1 were 0.42 g·L , 22.5% and 93.8 mg·L , respectively.LX1 reduced more significantly than those of sp. HQ.LX1 cells flocculated easily, particularly under low-nutrient conditions.LX1 outperforms sp. HQ.

Keywords： <i>Scenedesmusi> sp. LX1     <i>Chlorellai> sp.    

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Title Author Date Type Operation

<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Journal Article

Deciphering the Origins of P1-Induced Power Losses in Cu(In<i>xi>,Ga1–<i>xi>)Se2 (CIGS) Modules Through Hyperspectral Luminescence

César Omar Ramírez Quiroz, Laura-Isabelle Dion-Bertrand, Christoph J. Brabec, Joachim Müller, Kay Orgassa

Journal Article

Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Journal Article

<i>NES1i>/<i>KLK10i> and <i>hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Journal Article

Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Journal Article

Identification of genome regions and important variations associated with expression level of

Ye HOU,Lu JING,Yunxia ZHAO,Sheng WANG,An LIU,Shuhong ZHAO,Xinyun LI

Journal Article

SARS-CoV-2 Entry Factors: <i>ACE2i> and <i>TMPRSS2i> Are Expressed in Peri-Implantation Embryos and

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressiveFAT1 and inhibits stemness maintenance in thyroid carcinoma

Journal Article

<i>Ni>-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probesfor <i>in vivoi> cell H2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Journal Article

Evaluation of H2 on the Evolution Mechanism of NO<i>xi> Storage and Reductionover Pt–Ba–Ce/γ-Al2O3 Catalysts

Pan Wang, Jing Yi, Chuan Sun, Peng Luo, Lili Lei

Journal Article

Band-gap tunable (Ga<i>xi>In1−<i>xi>)2O3 layer

Fabi Zhang, Jinyu Sun, Haiou Li, Juan Zhou, Rong Wang, Tangyou Sun, Tao Fu, Gongli Xiao, Qi Li, Xingpeng Liu, Xiuyun Zhang, Daoyou Guo, Xianghu Wang, Zujun Qin,zhangfabi@outlook.com,qinzj@guet.edu.cn

Journal Article

NO<i>xi> and H2S formation in the reductive zone of air-staged combustion of

Jinzhi CAI, Dan LI, Denggao CHEN, Zhenshan LI

Journal Article

Successful production of an all-female common carp (<i>Cyprinus carpioi> L.) population using <i>cyp17a1i>-deficient neomale carp

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Journal Article

Comparison of growth and lipid accumulation properties of two oleaginous microalgae under different nutrient conditions

Qiao ZHANG,Yu HONG

Journal Article