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SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract: Angiotensin-converting enzyme 2 (ACE2) is the receptor of both severe acute respiratory syndrome coronavirusIn order to investigate the potential risk of SARS-CoV-2 vertical transmission, we explored ACE2extravillous trophoblast (EVTs_24W) cells in the maternal–fetal interface, strongly co-expressed ACE2ACE2 showed no gender bias in post-implantation embryos but showed a significant gender differencein D6 TE, D6 primitive endoderms (PE), and ACE2 positive-expressing STB cells.

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Frontiers of Medicine   Pages 185-192 doi: 10.1007/s11684-020-0754-0

Abstract: originated from Wuhan (China), invades human cells via the receptor angiotensin converting enzyme II (ACE2Moreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infectionesophagus, kidney, bladder, and ileum, and located specific cell types (i.e., type II alveolar cells (AT2)

Keywords： 2019-nCoV     ACE2     single-cell RNA-seq    

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Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells

Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 252-263 doi: 10.1007/s11684-021-0837-6

Abstract: that cigarette smoke extract (CSE) and carcinogen benzo(a)pyrene (BaP) increase mRNA but trigger ACE2for ACE2 ubiquitination.ACE2 in lung tissues of non-smokers is higher than in smokers, consistent with the findings that tobaccocarcinogens downregulate ACE2 in mice.Tobacco carcinogens inhibit SARS-CoV-2 spike protein pseudovirions infection of the cells.

Keywords： SARS-CoV-2     tobacco smoke     benzo(a)pyrene     ACE2     Skp2    

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Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Article

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Engineering 2021, Volume 7, Issue 10,   Pages 1441-1451 doi: 10.1016/j.eng.2020.07.014

Abstract: All seven glycosylation sites in human angiotensin I converting enzyme 2 (hACE2) were found to be completelyglycosylation did not directly contribute to the binding affinity between HCoV-19 S protein and hACE2.including multiple methylated sites in both proteins and multiple sites with hydroxylproline in hACE2.Refined structural models of HCoV-19 S protein and hACE2 were built by adding N-glycan and PTMsThe PTM and glycan maps of HCoV-19 S protein and hACE2 provide additional structural details for studying

Keywords： N-glycosylation     COVID-19     Spike protein     hACE2     Structure    

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Study on neutron cross-section library generated for MCNP in in-hospital neutron irradiator mark 1 reactor

Wang Lipeng,Jiang Xinbiao,Zhao Zhumin,Zhu Yangni,Chen Lixin,Zhou Yongmao

Strategic Study of Chinese Academy of Engineering 2012, Volume 14, Issue 8,   Pages 42-46

Abstract: Accounting for the temperature range for reactor operation, a compact ENDF (ACE) data library was createdThe results showed that the ACE format library produced in this paper was correct and could be used reliably

Keywords： NJOY     ENDF/B VII.0     MCNP     ACE format    

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Fire Risk Evaluation for Historic Building of The Potala Pal ace

Zhuang Lei,Lu Shouxiang,Wang Fuliang

Strategic Study of Chinese Academy of Engineering 2007, Volume 9, Issue 3,   Pages 76-81

Abstract:

The Potala Palace was built in the7th century and it is famous for its great historic and cultural values. From the aspects of fire resource, equipment of fire fighting, evacuation of people and management of fire safety, the situation of fire hazard was investigated in detail. It is necessary to have an efficient approach to evaluate older buildings of significant historic values. Fire risk evaluation described in this paper is one kind of semi-quantitative methods. It uses a model of multiple attribute evaluation to produce a measure of relative fire risk. Weights are established to indicate the importance of fire risk parameters. Then, for each specific historic structure, parameter grades, i.e. ,the amount or degree that a parameter is present, are determined from information collected in the actual situation of the survey. Fire risk is evaluated by the scalar product of the parameter weights and grades, producing a single numerical value representing the level of fire safety provided in the building. Moreover, suggestions are given about fire prevention and protection.

Keywords： the Potala Palace     historical buildings     fire risk assessment     semi-quantitative methods     firehazard    

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Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 80-84 doi: 10.1007/s11705-008-0017-0

Abstract: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioester(III), an importantintermediate of the fourth generation cephalosporins, was efficiently synthesized by reacting 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid (I) with 2,2′-dibenzothiazole disulfide (II) in

Keywords： 5-Amino-1     2     4-thiadiazol-3-yl     1     2-dichloroethane     important intermediate     2-benzothiazolyl thioester     temperature    

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Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 2,   Pages 142-146 doi: 10.1007/s11705-009-0233-2

Abstract: TiO-AlOmixed oxides with different compositions ranging from 40wt-% to 95wt-% of TiO were prepared by sol-gel method and impregnated with different amounts of VO. Supports and catalysts were characterized by X-ray diffraction (XRD), physisorption, temperature preprogrammed reduction (H-TPR), and ammonia temperature programmed desorption (NH-TPD). TiO content in the support had obvious effect on the crystal structure, texture characteristic, acid property, and catalytic activity in dehydrogenation of ethylbenzene (EB) with carbon dioxide. The highest catalytic activity was acquired when the TiO content was 50 wt-%.

Keywords： desorption     different     TiO-AlOmixed     physisorption     ethylbenzene    

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Al2O3 and CeO2-promoted MgO sorbents for CO2 capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1,   Pages 83-93 doi: 10.1007/s11705-017-1691-6

Abstract: A series of Al O and CeO modified MgO sorbents was prepared and studied for CO sorption at moderate temperatures. The CO sorption capacity of MgO was enhanced with the addition of either Al O or CeO . Over Al O -MgO sorbents, the best capacity of 24.6 mg-CO /g-sorbent was attained at 100 °C, which was 61% higher than that of MgO (15.3 mg-CO /g-sorbent). The highest capacity of 35.3 mg-CO /g-sorbent was obtained over the CeO -MgO sorbents at the optimal temperature of 200 °C. Combining with the characterization results, we conclude that the promotion effect on CO sorption with the addition of Al O and CeO can be attributed to the increased surface area with reduced MgO crystallite size. Moreover, the addition of CeO increased the basicity of MgO phase, resulting in more increase in the CO capacity than Al O promoter. Both the Al O -MgO and CeO -MgO sorbents exhibited better cyclic stability than MgO over the course of fifteen CO sorption-desorption cycles. Compared to Al O , CeO is more effective for promoting the CO capacity of MgO. To enhance the CO capacity of MgO sorbent, increasing the basicity is more effective than the increase in the surface area.

Keywords： CO2 capture     MgO sorbents     Al2O3     CeO2     flue gas    

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A Storage-Driven CO2 EOR for a Net-Zero Emission Target Article

Yueliang Liu,Zhenhua Rui,

Engineering 2022, Volume 18, Issue 11,   Pages 79-87 doi: 10.1016/j.eng.2022.02.010

Abstract: >2 emissions by storing CO2 in oil reservoirs.CO2 EOR—whose main target is to realize net-zero or even negative CO2 emissionsStorage-driven CO2 EOR is superior to conventional CO2 EOR in improving sweepingthan conventional CO2 EOR.Moreover, the amount of sequestrated CO2 in storage-driven CO2 EOR exceeds the amount

Keywords： CO2     EOR     Net CO2     emissions     Dimethyl ether     Storage-driven CO2     EOR     CO2     sequestration    

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CO2 methanation and co-methanation of CO and CO2 over Mn-promoted Ni/Al2

Kechao Zhao,Zhenhua Li,Li Bian

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2,   Pages 273-280 doi: 10.1007/s11705-016-1563-5

Abstract: A series of Mn-promoted 15 wt-% Ni/Al O catalysts were prepared by an incipient wetness impregnation method. The effect of the Mn content on the activity of the Ni/Al O catalysts for CO methanation and the co-methanation of CO and CO in a fixed-bed reactor was investigated. The catalysts were characterized by N physisorption, hydrogen temperature-programmed reduction and desorption, carbon dioxide temperature-programmed desorption, X-ray diffraction and high-resolution transmission electron microscopy. The presence of Mn increased the number of CO adsorption sites and inhibited Ni particle agglomeration due to improved Ni dispersion and weakened interactions between the nickel species and the support. The Mn-promoted 15 wt-% Ni/Al O catalysts had improved CO methanation activity especially at low temperatures (250 to 400 °C). The Mn content was varied from 0.86% to 2.54% and the best CO conversion was achieved with the 1.71Mn-Ni/Al O catalyst. The co-methanation tests on the 1.71Mn-Ni/Al O catalyst indicated that adding Mn markedly enhanced the CO methanation activity especially at low temperatures but it had little influence on the CO methanation performance. CO methanation was more sensitive to the reaction temperature and the space velocity than the CO methanation in the co-methanation process.

Keywords： Mn promotion     nickel catalysts     CO2 methanation     co-methanation of CO and CO2    

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Biodegradation of 2-methylisoborneol by bacteria enriched from biological activated carbon

Rongfang YUAN, Beihai ZHOU, Chunhong SHI, Liying YU, Chunlei ZHANG, Junnong GU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5,   Pages 701-710 doi: 10.1007/s11783-011-0367-6

Abstract: One of the most common taste and odour compounds (TOCs) in drinking water is 2-methylisoborneol (2-MIBFour bacterial strains for degrading 2-MIB were isolated from the surface of a biological activated carbonThe removal efficiencies of 2-MIB with initial concentrations of 515 ng·L were 98.4%, 96.3%, 95.0%,The kinetic model showed that biodegradation of 2-MIB at an initial dose of 4.2 mg·L was a pseudo-first-orderThese degraders decomposed 2-MIB to form 2-methylenebornane and 2-methyl-2-bornane as the products.

Keywords： 2-methylisoborneol (2-MIB)     biodegradation     2-methylenebornane     2-methyl-2-bornane     pseudo-first-order reaction    

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Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 672-683 doi: 10.1007/s11705-019-1856-6

Abstract: The conventional emulsion technique was selected for the microcapsule formulation by using 2-amino-2-

Keywords： carbon capture     microencapsulated sorbents     emulsion technique     low temperature adsorption and absorption    

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Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4,   Pages 343-348 doi: 10.1007/s11705-007-0062-0

Abstract: The cationic ring-opening copolymerization of AMO with another oxetane-derived monomer, 3-(2-(2-(2-methoxyethylenoxy

Keywords： 4-butanediol     2-methoxyethylenoxy     consistent     oxetane-derived     copolymer    

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Discussion on a new paradigm of endogenous security towards 6G networks Review

Xinsheng JI, Jiangxing WU, Liang JIN, Kaizhi HUANG, Yajun CHEN, Xiaoli SUN, Wei YOU, Shumin HUO, Jing YANG

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 10,   Pages 1421-1450 doi: 10.1631/FITEE.2200060

Abstract:

The sixth-generation mobile communication (6G) networks will face more complex endogenous security problems, and it is urgent to propose new universal security theories and establish new practice norms to deal with the "unknown unknown" security threats in cyberspace. This paper first expounds the new paradigm of cyberspace endogenous security and introduces the vision of 6G cyberspace security. Then, it analyzes the security problems faced by the 6G , , and emerging associated technologies in detail, as well as the corresponding security technology development status and the integrated development of endogenous security and traditional security. Furthermore, this paper describes the relevant security theories and technical concepts under the guidance of the .

Keywords： 6G security     New paradigm of endogenous security     Core network     Wireless access network    

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Title Author Date Type Operation

SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Journal Article

Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells

Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou

Journal Article

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals

Zeyu Sun, Keyi Ren, Xing Zhang, Jinghua Chen, Zhengyi Jiang, Jing Jiang, Feiyang Ji, Xiaoxi Ouyang, Lanjuan Li

Journal Article

Study on neutron cross-section library generated for MCNP in in-hospital neutron irradiator mark 1 reactor

Wang Lipeng,Jiang Xinbiao,Zhao Zhumin,Zhu Yangni,Chen Lixin,Zhou Yongmao

Journal Article

Fire Risk Evaluation for Historic Building of The Potala Pal ace

Zhuang Lei,Lu Shouxiang,Wang Fuliang

Journal Article

Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Journal Article

Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Journal Article

Al2O3 and CeO2-promoted MgO sorbents for CO2 capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Journal Article

A Storage-Driven CO2 EOR for a Net-Zero Emission Target

Yueliang Liu,Zhenhua Rui,

Journal Article

CO2 methanation and co-methanation of CO and CO2 over Mn-promoted Ni/Al2

Kechao Zhao,Zhenhua Li,Li Bian

Journal Article

Biodegradation of 2-methylisoborneol by bacteria enriched from biological activated carbon

Rongfang YUAN, Beihai ZHOU, Chunhong SHI, Liying YU, Chunlei ZHANG, Junnong GU

Journal Article

Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Journal Article

Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Journal Article

Discussion on a new paradigm of endogenous security towards 6G networks

Xinsheng JI, Jiangxing WU, Liang JIN, Kaizhi HUANG, Yajun CHEN, Xiaoli SUN, Wei YOU, Shumin HUO, Jing YANG

Journal Article