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Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: immune response is the first line of defense against viral invasion and pro-inflammatory chemokines and cytokinesThe ability of a rabies virus (RABV) to induce the expression of chemokines and cytokines can lead toIn this review, the crucial contribution of chemokines/cytokines to clearing RABV from the CNS is discussedIn addition, recombinant RABV expressing cytokines and chemokines can induce elevated innate and adaptive

Keywords： antiviral     blood brain barrier     chemokines and cytokines     innate immunity     rabies virus    

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Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 314-329 doi: 10.1007/s11684-018-0625-0

Abstract: The biological relevance of cytokines is known for more than 20 years.Evidence suggests that adipogenesis is one of the biological events involved in the regulation of cytokines, and pro-inflammatory cytokines (e.g., TNF and IL-1 ) inhibit adipogenesis through various pathwaysThis review focuses on the cytokines currently known to regulate adipogenesis under physiological andAlthough the interplay of cytokines and lipid metabolism is yet incompletely understood, cytokines represent

Keywords： cytokines     inflammation     adipogenesis     type 2 diabetes mellitus     metabolic disorder    

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The relationship between progesterone and Th-related cytokines in plasma during early pregnancy in cows

Lei CHENG,Youdong XIN,Xiaohua LIU,Xiuzhong HU,Min XIANG,Dingfa WANG,Shuhong ZHAO

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 147-152 doi: 10.15302/J-FASE-2016099

Abstract: pregnancy and successful embryo development is dependent on the maternal immunomodulation of Th-related cytokinesTherefore, we evaluated plasma P4 concentrations and expressions of three Th-related cytokines, interleukinsThe cytokines measured were not affected in either the high-P4 group (>11.1 ng·mL ) or the low-P4 groupA weak negative correlation between IL-1β and IL-6 was observed, but none of the cytokines was associated

Keywords： dairy cow     progesterone     pregnancy     cytokine    

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Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 418-424 doi: 10.1007/s11684-013-0297-8

Abstract:

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated accelerated platelet destruction and/or suppressed platelet production. Although the development of autoantibodies against platelet glycoproteins remains central in the pathophysiology of ITP, several abnormalities involving the cellular mechanisms of immune modulation have been identified, and the pathways behind the immune-mediated destruction of platelets have opened new avenues for the design of specific immunotherapies in an attempt to reduce the platelet destruction. This review is primarily focused on the recent literature with respect to immunopathological mechanisms in patients with ITP.

Keywords： primary immune thrombocytopenia     B lymphocytes     T lymphocytes     antigen-presenting cells     cytokines    

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Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 909-918 doi: 10.1007/s11684-021-0890-1

Abstract: initial cytokine profiling using plasma samples from 39 patients and 18 healthy donors found a series of cytokinesIn addition, verification in 81 patients with APL demonstrated that the two cytokines were positively

Keywords： acute promyelocytic leukemia     intracranial hemorrhage     cytokines     biomarker    

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Current State of Monoclonal Antibody Therapy for Allergic Diseases Review

Yan Chen, Wei Wang, Huihui Yuan, Yan Li, Zhe Lv, Ye Cui, Jie Liu, Sun Ying

Engineering 2021, Volume 7, Issue 11,   Pages 1552-1556 doi: 10.1016/j.eng.2020.06.029

Abstract: can promote or trigger T helper 2 (Th2)-type immune responses, leading to production of the type 2 cytokines(IL-33) have been also described and proposed to develop monoclonal antibodies against either these cytokinesThe present review aims to briefly outline the role of monoclonal antibodies targeting the cytokines

Keywords： Allergic disease     Monoclonal antibody     Anti-IgE     Cytokines     Clinical trials    

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Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the Toll-like receptor 4 signaling pathway

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 292-301 doi: 10.1007/s11684-020-0806-5

Abstract: The mRNA expression and the production of inflammatory cytokines were determined using quantitative real-time

Keywords： bioactive hyaluronan     lipopolysaccharide     inflammatory cytokines     TLR4     human macrophages    

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortality of patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: In addition, there were significant differences in the expression of several cytokines related to liverThe mechanism may be related to the role of RLR treatment in influencing cytokines related to liver regeneration

Keywords： virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration microenvironment     cytokines    

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Temporal Profiles of Antibody Responses, Cytokines, and Survival of COVID-19 Patients: A Retrospective Article

Li Liu, Heng-Gui Chen, Ying Li, Huijun Li, Jiaoyuan Li, Yi Wang, Shuang Yao, Chuan Qin, Shutao Tong, Xu Yuan, Xia Luo, Xiaoping Miao , An Pan, Zheng Liu, Liming Cheng

Engineering 2021, Volume 7, Issue 7,   Pages 958-965 doi: 10.1016/j.eng.2021.04.015

Abstract: profiles of specific antibodies, as well as the associations between the antibodies, proinflammatory cytokinesThe temporal profiles of the virus, antibodies, and cytokines of the patients until 12 weeks since illnessThe mediation effect of cytokines on the associations between antibody responses and survival were exploreddischarged patients, and 12.5% of the association between IgG level and mortality risk was mediated by these cytokines

Keywords： Coronavirus disease 2019     Antibody response     Cytokine     Mortality     Viral load    

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Title Author Date Type Operation

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Journal Article

Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Journal Article

The relationship between progesterone and Th-related cytokines in plasma during early pregnancy in cows

Lei CHENG,Youdong XIN,Xiaohua LIU,Xiuzhong HU,Min XIANG,Dingfa WANG,Shuhong ZHAO

Journal Article

Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Journal Article

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic leukemia

Journal Article

Current State of Monoclonal Antibody Therapy for Allergic Diseases

Yan Chen, Wei Wang, Huihui Yuan, Yan Li, Zhe Lv, Ye Cui, Jie Liu, Sun Ying

Journal Article

Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the Toll-like receptor 4 signaling pathway

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortality of patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Temporal Profiles of Antibody Responses, Cytokines, and Survival of COVID-19 Patients: A Retrospective

Li Liu, Heng-Gui Chen, Ying Li, Huijun Li, Jiaoyuan Li, Yi Wang, Shuang Yao, Chuan Qin, Shutao Tong, Xu Yuan, Xia Luo, Xiaoping Miao , An Pan, Zheng Liu, Liming Cheng

Journal Article