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Impact of diabetes and its treatments on skeletal diseases

Wenbo Yan, Xin Li

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 81-90 doi: 10.1007/s11684-013-0243-9

Abstract:

Diabetes mellitus is an enormous menace to public health globally.Both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are associated with an increasedHow diabetes accelerates the deterioration of cartilage remains largely unknown.influence skeletal tissues is in great need in view of the growing and aging population of patients with diabetes

Keywords： diabetes     bone     osteoporosis     osteoarthritis    

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New practice in semaglutide on type-2 diabetes and obesity: clinical evidence and expectation

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 17-24 doi: 10.1007/s11684-021-0873-2

Abstract: Obesity is an important risk factor of type 2 diabetes (T2D), which has become an important factor threatening

Keywords： semaglutide     type 2 diabetes     obesity    

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Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 624-633 doi: 10.1007/s11684-018-0669-1

Abstract:

Although type 2 diabetes is a disease often associated with aging, the global prevalence of early-onsetdiabetes has been increasing due to man’s sedentary lifestyle, low-physical activity, obesity, and somevascular complications than those with late-onset diabetes.Individuals with early-onset diabetes are usually unwilling to visit hospital and have more confidencein their health, which results in poor glycemic control and the delayed detection of diabetes-related

Keywords： diabetes     early-onset     diabetes complications    

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Metabolomics in human type 2 diabetes research

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 4-13 doi: 10.1007/s11684-013-0248-4

Abstract:

The high prevalence of diabetes and diabetic complications has caused a huge burden on the modernAlthough scientific advances have led to effective strategies for preventing and treating diabetes overThere is still a lack of reliable biomarkers indicative of metabolic alterations associated with diabetesRecent studies using metabolomics approach coupled with statistical tools to predict incident diabetes, type 2 diabetes.

Keywords： metabolomics     type 2 diabetes     metabolic pathway     mass spectrometry     nuclear magnetic resonance (NMR)    

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Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population

Palka Kaur Khanuja,Satish Chander Narula,Rajesh Rajput,Rajinder Kumar Sharma,Shikha Tewari

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 110-119 doi: 10.1007/s11684-016-0484-5

Abstract: A total of 207 patients with type 2 diabetes and chronic periodontitis (CP) were divided according toAfter controlling for age, gender, body mass index (BMI), socioeconomic status (SES), family history of diabetesand periodontitis, duration of diabetes, the mean PISA in mm2, PPD 4--6 mm (%) and PPD&ge

Keywords： type 2 diabetes mellitus     hemoglobin A     glycated     chronic periodontitis    

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A case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation

Xiaoyan Chen, Xiaochun Huang, Yuan Qiu, Hanzhang Chen, Yingyu Fu, Xinchun Li

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 143-146 doi: 10.1007/s11684-013-0238-6

Abstract: We report a case of thymic LCH with diabetes insipidus as the first presentation, without evidence of

Keywords： diabetes insipidus     thymus     Langerhans cell histiocytosis    

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Effectiveness of quality of care for patients with type 2 diabetes in China: findings from the Shanghai

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 126-138 doi: 10.1007/s11684-021-0897-7

Abstract: This cross-sectional study aimed to investigate the quality of care of diabetes in Shanghai, China.A total of 173 235 patients with type 2 diabetes in 2017 were included in the analysis.The patients had a mean age of 66.43±8.12 (standard deviation (SD)) years and a mean diabetes durationfactors associated with a great likelihood of achieving all three target levels: male, young age, short diabetesIn conclusion, nearly 50% and one-third of the patients with diabetes met the target levels for HbA

Keywords： type 2 diabetes     quality of care     macrovascular complication     microvascular complication     treatment pattern    

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Oxidative stress and diabetes: antioxidative strategies

Pengju Zhang, Tao Li, Xingyun Wu, Edouard C. Nice, Canhua Huang, Yuanyuan Zhang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 583-600 doi: 10.1007/s11684-019-0729-1

Abstract: Diabetes mellitus is one of the major public health problems worldwide.reduction–oxidation (redox) imbalance leads to oxidative stress and subsequent occurrence and development of diabetesspecies (ROS) can also directly oxidize certain proteins (defined as redox modification) involved in the diabetestherefore focused on the role of oxidative stress and antioxidative therapies in the pathogenesis of diabetesROS and downstream targets are now possible and provide important new insights into the treatment of diabetes

Keywords： diabetes     oxidative stress     redox modification     antioxidative therapy     novel antioxidant delivery    

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Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

Ranhua JIANG, Zhibo HAN, Guangsheng ZHUO, Xiaodan QU, Xue LI, Xin WANG, Yuankang SHAO, Shimin YANG, Zhong Chao HAN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 94-100 doi: 10.1007/s11684-011-0116-z

Abstract:

Mesenchymal stem cells (MSC) have been used in clinical trials for severe diabetes, a chronic diseaseHere, the therapeutic effect of human placenta-derived MSC (PD-MSC) was studied in type 2 diabetes patientsglycemic control in order to evaluate the safety, efficacy and feasibility of PD-MSC treatment in type 2 diabetes

Keywords： placenta stem cells     treatment of type 2 diabetes    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Diabetes has become a major public health problem in China nowadays.Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes.Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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Hybrid deep learning model for risk prediction of fracture in patients with diabetes and osteoporosis

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 496-506 doi: 10.1007/s11684-021-0828-7

Abstract: The fracture risk of patients with diabetes is higher than those of patients without diabetes due tohyperglycemia, usage of diabetes drugs, changes in insulin levels, and excretion, and this risk beginsmineral density, blood routine, and urine routine) may be related to bone metabolism in patients with diabetesIn addition, the fracture risk of patients with diabetes and osteoporosis has not been further studiedMoreover, the top 18 influencing factors of fracture risks of patients with diabetes are determined.

Keywords： XGBoost     deep neural network     healthcare     risk prediction    

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Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 174-177 doi: 10.1007/s11684-008-0032-z

Abstract: study demonstrates that therapy is effective on modulating dyslipidemia in newly diagnosed type 2 diabetes
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From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 191-200 doi: 10.1007/s11684-013-0258-2

Abstract: that the gut may influence the host’s metabolism and ultimately change the outcomes of type 2 diabetes

Keywords： gastric bypass     T2DM     gut    

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Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 678-687 doi: 10.1007/s11684-018-0671-7

Abstract:

Type 2 diabetes (T2D) has been associated with a high prevalence of depression.

Keywords： causal modeling     depression     Mendelian randomization     type 2 diabetes    

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Hyperglycemic memory in diabetic cardiomyopathy

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 25-38 doi: 10.1007/s11684-021-0881-2

Abstract: Cardiovascular diseases account for approximately 80% of deaths among individuals with diabetes mellitusAlthough glycemic control has long been at the center of diabetes therapy, multicenter randomized clinicalglycemic control fails to reduce heart failure-associated hospitalization and mortality in patients with diabetesfinding indicates that hyperglycemic stress persists in the cardiovascular system of patients with diabetes

Keywords： diabetes     diabetic cardiomyopathy     hyperglycemic memory    

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Title Author Date Type Operation

Impact of diabetes and its treatments on skeletal diseases

Wenbo Yan, Xin Li

Journal Article

New practice in semaglutide on type-2 diabetes and obesity: clinical evidence and expectation

Journal Article

Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Journal Article

Metabolomics in human type 2 diabetes research

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Journal Article

Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population

Palka Kaur Khanuja,Satish Chander Narula,Rajesh Rajput,Rajinder Kumar Sharma,Shikha Tewari

Journal Article

A case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation

Xiaoyan Chen, Xiaochun Huang, Yuan Qiu, Hanzhang Chen, Yingyu Fu, Xinchun Li

Journal Article

Effectiveness of quality of care for patients with type 2 diabetes in China: findings from the Shanghai

Journal Article

Oxidative stress and diabetes: antioxidative strategies

Pengju Zhang, Tao Li, Xingyun Wu, Edouard C. Nice, Canhua Huang, Yuanyuan Zhang

Journal Article

Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

Ranhua JIANG, Zhibo HAN, Guangsheng ZHUO, Xiaodan QU, Xue LI, Xin WANG, Yuankang SHAO, Shimin YANG, Zhong Chao HAN

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

Hybrid deep learning model for risk prediction of fracture in patients with diabetes and osteoporosis

Journal Article

Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Journal Article

From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Journal Article

Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Journal Article

Hyperglycemic memory in diabetic cardiomyopathy

Journal Article