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Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 300-309 doi: 10.1007/s11684-014-0357-8

Abstract:

The current modes of experience inheritance from famous specialists in traditional Chinese medicineHowever, a scientific and instructive experience inheritance mode has not been developed.research paradigm in the real world have provided new perspectives, techniques, and methods for inheriting experienceinnovation research mode based on the real-world TCM clinical research paradigm, which involves the inheritanceinheritance in the clinical field.

Keywords： traditional Chinese medicine (TCM)     real world     clinical research paradigm     famous specialist     experienceinheritance    

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exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational epigenetic inheritance

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 176-184 doi: 10.1007/s11684-021-0885-y

Abstract: synthetically identified sncRNAs gradually lifted the veil of sncRNA regulation during intergenerational inheritancespermatozoal sncRNAs, (2) potential role of paternal spermatozoal sncRNAs during the intergenerational inheritanceprocess, and (3) the potential mechanism by which spermatozoal sncRNAs meditate intergenerational inheritance, increased attention highlights the hidden wonder of spermatozoal sncRNAs during intergenerational inheritance

Keywords： small noncoding RNAs     epigenetic inheritance     paternal intergenerational inherence     extracellular vesicles    

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Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 419-426 doi: 10.1007/s11684-014-0383-6

Abstract:

Aneurysmal dilatation of the aortic sinuses of Valsalva has been most extensively documented in the setting of aortopathies, particularly Marfan syndrome. On the other hand, there is limited data in the literature about congenital sinus of Valsalva aneurysms outside this context. For the purpose of this review, we carried out a literature search on aneurysmal dilatation of the sinuses of Valsalva in Marfan syndrome, and compared this with congenital sinus of Valsalva aneurysms, also including data from a case series from our institution. In conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital sinus of Valsalva aneurysms. Though less well-recognised, congenital aneurysms are often associated with significant morbidity and mortality and timely intervention is necessary.

Keywords： sinus of Valsalva aneurysms     Marfan syndrome     aortic dissection    

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Taizhou’s COVID-19 prevention and control experience with telemedicine features

Cenyi Shao, Shijian Li, Feng Zhu, Dahai Zhao, Hui Shao, Haixiao Chen, Zhiruo Zhang

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 506-510 doi: 10.1007/s11684-020-0811-8

Abstract: We summarize Taizhou’s COVID-19 prevention and control experience with telemedicine features, with a

Keywords： COVID-19     telemedicine     prevention experience    

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Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic inheritance

Frontiers of Medicine 2023, Volume 17, Issue 5,   Pages 1006-1009 doi: 10.1007/s11684-023-1000-3

Abstract: Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic inheritance

Keywords： family craniofacial microsomia     Identification novel mutations    

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Thinking and practice of accelerating transformation of traditional Chinese medicine from experience

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 163-170 doi: 10.1007/s11684-011-0143-9

Abstract: The gradual development of Chinese medicine is based on constant accumulation and summary of experiencethousands of years, with the development of evidence-based medicine, the bondage of the research methods of experienceThe rapid transition and transformation from experience medicine to evidence-based medicine have becomescientific and reliable evidence of Chinese medicine, as well as transform and develop Chinese medicine from experience

Keywords： Chinese medicine     experience medicine     evidence-based medicine     real world    

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Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

Lulu Ma, Wei Liu, Yuguang Huang

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 395-395 doi: 10.1007/s11684-013-0289-8

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Knowledge-based competitive strategy using direct customer experience for automobile product development

Peter HODGES, Shuh Yuan LIOU,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 1,   Pages 33-46 doi: 10.1007/s11465-009-0080-3

Abstract: The automobile product development (PD) design space continually increases in size and complexity. In this dynamic environment, firms must identify competitive strategies that maintain or increase financial return. Firms can compete on several factors including price/cost, time-to-market, or differentiation (e.g., function or quality). Here, we envision that differentiation through expertise in integration can be a successful strategy in the automotive industry. Expertise in integration requires attention to knowledge management, which is crucial for competitive advantage []. A key component of the PD process is the acquisition of data about customers’ responses to vehicle performance and the rapid use of that information in the development of new products. The paper proposes a system for collecting near real-time data about responses to vehicle performance and its integration with recent developments in design and analysis. The proposed system would collect customer psychophysical response data, correlate it with vehicle parameter response data, and apply this information with feasible design automation to provide reduced cycle time, improved quality, and greater customer satisfaction. The paper discusses some relevant technological and legal constraints and concludes that such a system is feasible, can provide a near-term competitive advantage, and in the long-term, in some form, will be necessary for success.

Keywords： product development     strategy     knowledge management    

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Inheritance and Innovation of Engineering Management Informatization

Kai Sun,Ren-huai Liu

Frontiers of Engineering Management 2014, Volume 1, Issue 1,   Pages 76-82 doi: 10.15302/J-FEM-2014014

Abstract: In the life-cycle of large projects, the operational phase lasts the longest, costs the most and substantially benefits the project. During the whole phase, energy, material and human resources may cost a lot. Effective control of such costs is one of the main targets of engineering management informatization. How to lower the organization collaboration cost in project management and how to support effective collaboration among different areas, organizations and departments in the ways of technology and management are major goals in engineering management informatization. In the phase of project operation, project owners, partners and customers are the stakeholders of engineering management informatization. Through the case of airport management informatization, inherited and innovation of engineering management informatization will be discussed. It is illustrated that airport informatization is the innovation of business model and technology applications through the analysis and study on cases of airport informatization.

Keywords： engineering management     informatization     inter-organizational relationship     management creation     resource sharing    

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A stepwise process for carbon dioxide sequestration using magnesium silicates

Johan FAGERLUND, Experience NDUAGU, Ron ZEVENHOVEN, Inês ROMÃO,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 2,   Pages 133-141 doi: 10.1007/s11705-009-0259-5

Abstract: This work involves the production of magnesium in the form of Mg(OH) from serpentinite rock (nickel mine tailing) material followed by conversion into MgCO using a pressurised fluidised bed (PFB) reactor operating at 400°C–600°C and pressures up to 2.85MPa. Our approach is rooted in the thermodynamic fact that the reaction between Mg(OH) and gaseous CO forming MgCO and water releases significant amounts of heat. The main problem is, however, the chemical kinetics; the reaction is slow and has to be accelerated in order to be used in an economically viable process for large-scale (~1Mt/a) CO sequestration. We have constructed a lab-scale PFB reactor test-setup for optimising the carbonation reaction. At high enough temperatures and conversion levels the reaction should provide the heat for the proceeding Mg(OH) production step, making the overall process energy neutral. So far we have been able to achieve a conversion degree of 26% at 500°C and 2.85MPa after 30min (particle size 125–212μm). In this paper the test facility and our latest results and progress on CO mineral carbonation are summarised. Also, the possible integration of the iron as a feedstock for iron and steel production will be briefly addressed. An interesting side-effect of this carbon dioxide capture and storage (CCS) route is that significant amounts of iron are obtained from the serpentinite rock material. This is released during the Mg(OH) production and can be of great interest to the iron- and steel producing sector, which at the same time is Finland’s largest CO producer.

Keywords： carbonation reaction     reactor     producer     large-scale     process    

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Practice and Experience of Canton Tower Project Management

Rong-hua Yi

Frontiers of Engineering Management 2016, Volume 3, Issue 1,   Pages 74-79 doi: 10.15302/J-FEM-2016013

Abstract: This paper presents a brief introduction about the preliminary consulting and tender agent of Canton Tower, the basic situation of the whole-process supervision on the construction site, and a general summary of the Canton Tower project management. What’s more, the author suggests that some guidelines be formed for supervision enterprises involved in large-scale project management.

Keywords： Canton Tower     consultation     tender agent     whole-process     supervision    

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The Rise of No/Low Code Software Development—No Experience Needed?

Marcus Woo

Engineering 2020, Volume 6, Issue 9,   Pages 960-961 doi: 10.1016/j.eng.2020.07.007

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Diagnosis and treatment for advanced hilar cholangiocarcinoma: experience of 24 cases

ZHANG Zongming, ZHU Jianping, SU Yanming, GUO Jinxing, JIANG Nan, ZHANG Zichao, XING Hailin, LIU Kai, YUAN Haiming

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 134-138 doi: 10.1007/s11684-008-0025-y

Abstract: The aim of this paper is to evaluate the efficacy of the surgical treatment for advanced hilar cholangiocarcinoma (CCA) in order to improve the resection rate and curative effect. A retrospective analysis was performed on the data of 24 patients who had undergone surgical treatment for advanced hilar CCA. According to the Bismuth classification, there were four cases of type IIIa, six cases of type IIIb, and 14 cases of type IV. Based on the treatment approaches, these patients were divided into three groups: $` Radical resection group: There were five cases (one type IIIa, three type IIIb, and one type IV). The tumor visible to the naked eyes was resected thoroughly and the cut margin was free of tumor by microscopic examination. Then, Roux-en-Y hepatico-jejunal anastomosis was performed to restore the bile flow. $a Palliative resection group: There were 11 cases. The bile flow was restored by Roux-en-Y hepatico-jejunal anastomosis directly in five cases (two type IIIa, three type IIIb) and by internal drainage through a hepatico-jejunal bridge in the other six cases (one type IIIa, five type IV). $b Simple internal biliary drainage group: There were eight cases of type IV, including three cases with the internal drainage through hepatico-jejunal bridge by laparotomy, three cases with endoscopic retrograde biliary drainage (ERBD), two cases with percutaneous transhepatic biliary drainage (PTBD). The rate of radical resection was 20.8% and the overall resection rate was 66.7%. All of the 24 patients were followed-up. The cumulative surviving rates were significantly different among these three groups (Log-rank = 17.56, = 0.0002). For advanced hilar CCA, the best choice of treatment is radical resection. If radical resection is impractical, palliative resection combined with partial hepatectomy can significantly prolong the survival time. Internal drainage through a hepatico-jejunal bridge can enhance the surgical resection rate and decrease the occurrence rate of postoperative biliary leakage.
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Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic

Meng Lv, Yingjun Chang, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 45-56 doi: 10.1007/s11684-017-0595-7

Abstract: multicenter studies adhering to international standards facilitated the transformation of the unique Chinese experience

Keywords： haploidentical hematopoietic stem cell transplantation     conditioning     graft-versus-host disease     relapse     infection     donor selection    

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Cryotherapy for cirrhosis-based hepatocellular carcinoma: a single center experience from 1595 treated

Guanghua Rong,Wenlin Bai,Zheng Dong,Chunping Wang,Yinying Lu,Zhen Zeng,Jianhui Qu,Min Lou,Hong Wang,Xudong Gao,Xiujuan Chang,Linjing An,Yan Chen,Yongping Yang

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 63-71 doi: 10.1007/s11684-014-0342-2

Abstract: We report our experience in treating 1595 HCC cases with percutaneous cryoablation to give a comprehensive

Keywords： hepatocellular carcinoma     percutaneous cryoablation     efficacy     safety    

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Title Author Date Type Operation

Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Journal Article

exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational epigenetic inheritance

Journal Article

Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

Maryanne Caruana,Mary N. Sheppard,Wei Li

Journal Article

Taizhou’s COVID-19 prevention and control experience with telemedicine features

Cenyi Shao, Shijian Li, Feng Zhu, Dahai Zhao, Hui Shao, Haixiao Chen, Zhiruo Zhang

Journal Article

Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic inheritance

Journal Article

Thinking and practice of accelerating transformation of traditional Chinese medicine from experience

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

Journal Article

Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

Lulu Ma, Wei Liu, Yuguang Huang

Journal Article

Knowledge-based competitive strategy using direct customer experience for automobile product development

Peter HODGES, Shuh Yuan LIOU,

Journal Article

Inheritance and Innovation of Engineering Management Informatization

Kai Sun,Ren-huai Liu

Journal Article

A stepwise process for carbon dioxide sequestration using magnesium silicates

Johan FAGERLUND, Experience NDUAGU, Ron ZEVENHOVEN, Inês ROMÃO,

Journal Article

Practice and Experience of Canton Tower Project Management

Rong-hua Yi

Journal Article

The Rise of No/Low Code Software Development—No Experience Needed?

Marcus Woo

Journal Article

Diagnosis and treatment for advanced hilar cholangiocarcinoma: experience of 24 cases

ZHANG Zongming, ZHU Jianping, SU Yanming, GUO Jinxing, JIANG Nan, ZHANG Zichao, XING Hailin, LIU Kai, YUAN Haiming

Journal Article

Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic

Meng Lv, Yingjun Chang, Xiaojun Huang

Journal Article

Cryotherapy for cirrhosis-based hepatocellular carcinoma: a single center experience from 1595 treated

Guanghua Rong,Wenlin Bai,Zheng Dong,Chunping Wang,Yinying Lu,Zhen Zeng,Jianhui Qu,Min Lou,Hong Wang,Xudong Gao,Xiujuan Chang,Linjing An,Yan Chen,Yongping Yang

Journal Article