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2019 novel coronavirus outbreak: a quiz or final exam?

Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 225-228 doi: 10.1007/s11684-020-0753-1

Abstract: The 2019 novel coronavirus (2019-nCoV) is an emerging pathogen and is threatening the global health.clinicians, scientists, officials, and citizens in China are all contributing to the prevention of further 2019-nCoV-nCoV transmission.Efficient preliminary work has enabled us to understand the basic characteristics of 2019-nCoV, but there

Keywords： 2019-nCoV     novel coronavirus     epidemic     public response    

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Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19 in Wuhan

Li Ni, Ling Zhou, Min Zhou, Jianping Zhao, Dao Wen Wang

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 210-214 doi: 10.1007/s11684-020-0757-x

Abstract: In December 2019, an outbreak of novel coronavirus (2019-nCoV) occurred in Wuhan, Hubei Province, ChinaHere we report the first family case of coronavirus disease 2019 (COVID-19) confirmed in Wuhan and treated

Keywords： novel coronavirus (2019-nCoV)     COVID-19     Chinese traditional patent medicine     Shuanghuanglian oral liquid    

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China’s local governments are combating COVID-19 with unprecedented responses – from a Wenzhou governance perspective

Fanghua Gong, Yong Xiong, Jian Xiao, Li Lin, Xiaodong Liu, Dezhong Wang, Xiaokun Li

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 220-224 doi: 10.1007/s11684-020-0755-z

Abstract: The COVID-19 caused by a novel strain of coronavirus has been spreading rapidly since its onset in Wuhan, the capital city of central China’s Hubei Province, in December 2019.

Keywords： COVID-19     novel coronavirus pneumonia     2019-nCoV     epidemic management    

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Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions

Zhiruo Zhang, Shelan Liu, Mi Xiang, Shijian Li, Dahai Zhao, Chaolin Huang, Saijuan Chen

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 229-231 doi: 10.1007/s11684-020-0765-x

Abstract: The outbreak of a novel coronavirus disease (COVID-19, caused by the 2019-nCoV infection) in December2019 is one of the most severe public health emergencies since the founding of People’s Republic of

Keywords： healthcare personnel     COVID-19     infectious diseases    

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on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV-nCoV infection

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Frontiers of Medicine   Pages 185-192 doi: 10.1007/s11684-020-0754-0

Abstract:

It has been known that, the novel coronavirus, 2019-nCoV, which is considered similar to SARS-CoVMoreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infectionHowever, some patients also exhibit non-respiratory symptoms, such as kidney failure, implying that 2019-nCoVkidney, ileum and esophagus epithelial cells, and bladder urothelial cells), which are vulnerable to 2019-nCoVThis study may provide potential clues for further investigation of the pathogenesis and route of 2019-nCoV

Keywords： 2019-nCoV     ACE2     single-cell RNA-seq    

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Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID) Article

Xinyao Jin, Bo Pang, Junhua Zhang, Qingquan Liu, Zhongqi Yang, Jihong Feng, Xuezheng Liu, Lei Zhang, Baohe Wang, Yuhong Huang, Alice Josephine Fauci, Yuling Ma, Myeong Soo Lee, Wei’an Yuan, Yanming Xie, Jianyuan Tang, Rui Gao, Liang Du, Shuo Zhang, Hanmei Qi, Yu Sun, Wenke Zheng, Fengwen Yang, Huizi Chua, Keyi Wang, Yi Ou, Ming Huang, Yan Zhu, Jiajie Yu, Jinhui Tian, Min Zhao, Jingqing Hu, Chen Yao, Youping Li, Boli Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1147-1152 doi: 10.1016/j.eng.2020.03.002

Abstract:

Since its outbreak in December 2019, a series of clinical trials on coronavirus disease 2019 (COVIDThe COS-COVID includes one outcome for the mild type (time to 2019 novel coronavirus (2019-nCoV) reversethe ordinary type (length of hospital stay, composite events, score of clinical symptoms, and time to 2019-nCoV-nCoV RT-PCR negativity), five outcomes for the severe type (composite events, length of hospital staysub>)/fraction of inspired oxygen (FiO2), duration of mechanical ventilation, and time to 2019-nCoV

Keywords： Novel coronavirus pneumonia     Core outcome set     COVID-19     2019-nCoV     Coronavirus disease     Clinical trials    

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Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Frontiers of Medicine doi: 10.1007/s11684-023-1041-7

Abstract: The coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomics

Keywords： SARS-CoV-2     ischemic stroke     stroke     hemorrhagic stroke     cerebral venous thrombosis     vaccination    

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Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 126-135 doi: 10.1007/s11684-020-0767-8

Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoVThis novel virus spread mainly through respiratory droplets and close contact.

Keywords： coronavirus disease 2019     epidemiology     pathology     radiology     clinical characteristics     treatment    

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Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 126-130 doi: 10.1007/s11684-017-0603-y

Abstract: Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important

Keywords： Middle East respiratory syndrome coronavirus     MERS-CoV     pregnancy     pediatrics    

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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A Deep Learning System to Screen Novel Coronavirus Disease 2019 Pneumonia Article

Xiaowei Xu, Xiangao Jiang, Chunlian Ma, Peng Du, Xukun Li, Shuangzhi Lv, Liang Yu, Qin Ni, Yanfei Chen, Junwei Su, Guanjing Lang, Yongtao Li, Hong Zhao, Jun Liu, Kaijin Xu, Lingxiang Ruan, Jifang Sheng, Yunqing Qiu, Wei Wu, Tingbo Liang, Lanjuan Li

Engineering 2020, Volume 6, Issue 10,   Pages 1122-1129 doi: 10.1016/j.eng.2020.04.010

Abstract: viral RNA from sputum or nasopharyngeal swab had a relatively low positive rate in the early stage of coronavirusdisease 2019 (COVID-19).

Keywords： Coronavirus disease 2019 pneumonia     COVID-19     Location-attention classification model     Computed tomography    

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Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 111-119 doi: 10.1007/s11684-016-0446-y

Abstract:

The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memoriesof the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002.

Keywords： coronavirus     MERS     Middle East respiratory syndrome    

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Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 120-136 doi: 10.1007/s11684-016-0430-6

Abstract:

The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained

Keywords： MERS     coronavirus     review    

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Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 776-785 doi: 10.1007/s11684-020-0820-7

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus

Keywords： coronavirus disease 2019     pediatrics     emergency     retrospective investigation     severe acute respiratory syndromecoronavirus 2    

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Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

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Title Author Date Type Operation

2019 novel coronavirus outbreak: a quiz or final exam?

Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao

Journal Article

Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19 in Wuhan

Li Ni, Ling Zhou, Min Zhou, Jianping Zhao, Dao Wen Wang

Journal Article

China’s local governments are combating COVID-19 with unprecedented responses – from a Wenzhou governance perspective

Fanghua Gong, Yong Xiong, Jian Xiao, Li Lin, Xiaodong Liu, Dezhong Wang, Xiaokun Li

Journal Article

Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions

Zhiruo Zhang, Shelan Liu, Mi Xiang, Shijian Li, Dahai Zhao, Chaolin Huang, Saijuan Chen

Journal Article

on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV-nCoV infection

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Journal Article

Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID)

Xinyao Jin, Bo Pang, Junhua Zhang, Qingquan Liu, Zhongqi Yang, Jihong Feng, Xuezheng Liu, Lei Zhang, Baohe Wang, Yuhong Huang, Alice Josephine Fauci, Yuling Ma, Myeong Soo Lee, Wei’an Yuan, Yanming Xie, Jianyuan Tang, Rui Gao, Liang Du, Shuo Zhang, Hanmei Qi, Yu Sun, Wenke Zheng, Fengwen Yang, Huizi Chua, Keyi Wang, Yi Ou, Ming Huang, Yan Zhu, Jiajie Yu, Jinhui Tian, Min Zhao, Jingqing Hu, Chen Yao, Youping Li, Boli Zhang

Journal Article

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Journal Article

Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Journal Article

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

A Deep Learning System to Screen Novel Coronavirus Disease 2019 Pneumonia

Xiaowei Xu, Xiangao Jiang, Chunlian Ma, Peng Du, Xukun Li, Shuangzhi Lv, Liang Yu, Qin Ni, Yanfei Chen, Junwei Su, Guanjing Lang, Yongtao Li, Hong Zhao, Jun Liu, Kaijin Xu, Lingxiang Ruan, Jifang Sheng, Yunqing Qiu, Wei Wu, Tingbo Liang, Lanjuan Li

Journal Article

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Journal Article

Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Journal Article

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Journal Article