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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: However, a number of studies have shown that multiple types of pituitary hormone receptors are widelyEach pituitary gland-derived hormone exhibits a wide range of nonconventional biological effects in theseHerein, the extra biological functions of pituitary hormones, thyroid-stimulating hormone, follicle-stimulatinghormone, luteinizing hormone, adrenocorticotrophic hormone, and prolactin when they act on non-classicalorgans were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissue

Keywords： thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophichormone     prolactin    

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Long-term results of suppressing thyroid-stimulating hormone during radiotherapy to prevent primary hypothyroidism

Maura Massimino, Marta Podda, Lorenza Gandola, Emanuele Pignoli, Ettore Seregni, Carlo Morosi, Filippo Spreafico, Andrea Ferrari, Emilia Pecori, Monica Terenziani

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 101-107 doi: 10.1007/s11684-020-0752-2

Abstract: Primary hypothyroidism commonly occurs after radiotherapy (RT), and coincides with increased circulating thyroid-stimulatinghormone (TSH) levels., scheduled for craniospinal irradiation and mediastinum/neck radiotherapy, respectively, underwent thyroid

Keywords： iatrogenic primary hypothyroidism     late effects of radiotherapy     long-term follow-up     medulloblastoma     Hodgkin lymphoma    

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Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children duringtherapy with recombinant human growth hormone

Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 580-585 doi: 10.1007/s11684-017-0585-9

Abstract:

This study aimed to evaluate the effects of thyroid hormone supplementation on growth rate of childrenwith idiopathic short stature (ISS) and low-normal serum free thyroxine FT4 who were receiving growth hormoneDuring the first year, the lower FT4 group featured lower FT3, FT4, thyroid stimulating hormone (TSH)In children with ISS, the negative effect of thyroid hormone deficiency on growth rate should be consideredwhen FT4 level lies in the low-normal range prior to recombinant human growth hormone treatment.

Keywords： therapeutic     idiopathic short-stature children     free T4     the first year     recombinant human growth hormone    

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Clinical evaluation of recombinant human growth hormone injection in children with growth hormone deficiency

Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 171-176 doi: 10.1007/s11684-009-0027-4

Abstract: Recombinant human growth hormone (rhGH) has been widely used in the clinical treatment of growth hormonecurrent study was to evaluate the efficacy and safety of rhGH injection for the treatment of growth hormoneadverse events occurred during the treatment, and the drug-related adverse events were mainly decreased thyroidWe conclude that rhGH injection is a safe and effective drug for treatment of growth hormone deficiency

Keywords： recombinant human growth hormone     injection     growth hormone deficiency    

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The effect of orbital radiation therapy on thyroid-associated orbitopathy complicated with dysthyroid

Yang Wang, Huifang Zhou, Xianqun Fan

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 359-364 doi: 10.1007/s11684-017-0528-5

Abstract:

Thyroid-associated orbitopathy (TAO) is an inflammatory autoimmune disorder.

Keywords： thyroid-associated orbitopathy     dysthyroid optic neuropathy     orbital radiation therapy    

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How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 290-293 doi: 10.1007/s11684-010-0093-7

Abstract: The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, although

Keywords： breast cancer     postmenopausal hormone therapy     unopposed estrogen therapy     combined estrogen-progestin therapy    

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Intratumoral Bacteria Dysbiosis Is Associated with Human Papillary Thyroid Cancer and Correlated with Article

Shuang Yu, Yanqiang Ding, Xuejie Wang, Siu Kin Ng, Siting Cao, Weixin Liu, Zhuming Guo, Yubin Xie, Shubin Hong, Lixia Xu, Xiaoxing Li, Jie Li, Weiming Lv, Sui Peng, Yanbing Li, Joseph J.Y. Sung, Jun Yu, Haipeng Xiao

Engineering doi: 10.1016/j.eng.2023.01.007

Abstract: However, knowledge of whether the microbial community in thyroid tumor is related to tumorigenesis remainsIn this study, we aimed to explore the microbial community in thyroid tissues and its contribution topapillary thyroid cancer (PTC).Intra-thyroid tissue bacteria were verified by means of bacteria staining, fluorescence in situthyroid

Keywords： Papillary thyroid cancer     Benign thyroid nodule     Bacteria     Transcriptome     Hashimoto's thyroiditis    

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Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern

Lizhe Ai, Yaqin Yu, Xiaoli Liu, Chong Wang, Jieping Shi, Hui Sun, Qiong Yu

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 113-117 doi: 10.1007/s11684-014-0310-x

Abstract:

Papillary thyroid carcinoma (PTC) is one of the most common tumors of the thyroid gland.The common risk factors of PTC include ionizing radiation, positive family history, and thyroid nodular

Keywords： NKX2-1     papillary thyroid carcinoma     the Han population of Northern China     association    

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Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 16-20

Abstract: of estrogen and progestin, secondarily leading to suppression of endogenous gonadotropin and gonadal hormoneDuring the hormone-free interval (HFI), COCs users experience activation of their pituitary–ovarian

Keywords： COCs     HFI     hormone     follicle    

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RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract:

Fruit ripening is a complex developmental process made up of genetically programmed physiological and biochemical activities. It culminates in desirable changes in the structural and textural properties and is governed by a complex regulatory network. Much is known about ethylene, one of the most important metabolites promoting the ripening of climacteric fruits. However, the dynamic interplay between phytohormones also plays an important part. Additional regulatory factors such as transcription factors (TFs) and epigenetic modifications also play vital role in the regulation of climacteric fruit ripening. Here, we review and evaluate the complex regulatory network comprising interactions between hormones and the action of TFs and epigenetic modifications during climacteric fruit ripening.

 

Keywords： climacteric fruit ripening / phytohormones / TFs / epigenetic modifications    

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RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Yinglin JI, Mingyang XU, Aide WANG

Frontiers of Agricultural Science and Engineering   Pages 314-334 doi: 10.15302/J-FASE-2021386

Abstract: Fruit ripening is a complex developmental process made up of genetically programmed physiological and biochemical activities. It culminates in desirable changes in the structural and textural properties and is governed by a complex regulatory network. Much is known about ethylene, one of the most important metabolites promoting the ripening of climacteric fruits. However, the dynamic interplay between phytohormones also plays an important part. Additional regulatory factors such as transcription factors (TFs) and epigenetic modifications also play vital role in the regulation of climacteric fruit ripening. Here, we review and evaluate the complex regulatory network comprising interactions between hormones and the action of TFs and epigenetic modifications during climacteric fruit ripening.

Keywords： climacteric fruit ripening     phytohormones     TFs     epigenetic modifications    

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Analyses of levels of thyroid hormones and its receptor expression in puerperants and newborns from an

JU Ying, CHEN Lan, JIANG Qi, YANG Kedi, CHEN Xuemin, XU Guojian, LI Liping

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 276-282 doi: 10.1007/s11684-008-0052-8

Abstract: In this study, the serum levels, including thyroid hormones free triiodothyronine (FT), free thyroxine(FT),thyroid stimulating hormone(TSH)among the subjects from the exposed group ( = 48) and the controlThe correlations between the thyroid hormone levels in maternal serum and umbilical serum, and betweenaffect the health of local parturient women and newborns, representing changes both in serum levels of thyroid

Keywords： control     immuno radiometric     FT     TSH     exposed    

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mesenchymal stem cells promotes the expression of tumor-suppressive FAT1 and inhibits stemness maintenance in thyroid

Frontiers of Medicine doi: 10.1007/s11684-023-0999-5

Abstract: Through bioinformatics predictions, we identified that GTF2I and FAT1 were downregulated in thyroid carcinoma

Keywords： thyroid carcinoma     mesenchymal stem cell     extracellular vesicle     GTF2I     FAT1     CDK4    

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The study of ovary development and steroid hormone changes in Alosa sapidissima

Hong Lei,Li Zhaoxin,Chen Chao,Guo Zhenglong,Wang Weifang,Lei Jilin

Strategic Study of CAE 2014, Volume 16, Issue 9,   Pages 86-92

Abstract:

In this study, the morphological changes of ovary development and variation of correlated plasma sex steroids levels were detected in Alosa sapidissima. The result shown that Alosa sapidissima belongs to the non-synchronized multiple batch spawner; based on size, shape and external color, the development of ovary was divided into six stages; according to changes of inner structures, yolk accumulating and development of follicle cells, the oogenesis could be divided into six phases. There were no significant differences about hepatosomatic index (HSI) and condition factor (CF) during the ovarian maturation cycle, but gonadosomatic index (GSI) and 17β- estradiol (E2) were found to increase during the peak phase of vitellogenic growth corresponding to the ovary development.

Keywords： Alosa sapidissima     ovary development     oogenesis     histology     morphology     steroid hormone    

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Progress and challenges in RET-targeted cancer therapy

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 207-219 doi: 10.1007/s11684-023-0985-y

Abstract: Oncogenic RET fusions or mutations are found most often in non-small cell lung cancer (NSCLC) and in thyroid

Keywords： pralsetinib     selpercatinib     RET-alteration     lung cancer     thyroid cancer     tumor-agnostic therapy     drug    

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Title Author Date Type Operation

Atypical pituitary hormone–target tissue axis

Journal Article

Long-term results of suppressing thyroid-stimulating hormone during radiotherapy to prevent primary hypothyroidism

Maura Massimino, Marta Podda, Lorenza Gandola, Emanuele Pignoli, Ettore Seregni, Carlo Morosi, Filippo Spreafico, Andrea Ferrari, Emilia Pecori, Monica Terenziani

Journal Article

Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children duringtherapy with recombinant human growth hormone

Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng

Journal Article

Clinical evaluation of recombinant human growth hormone injection in children with growth hormone deficiency

Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU

Journal Article

The effect of orbital radiation therapy on thyroid-associated orbitopathy complicated with dysthyroid

Yang Wang, Huifang Zhou, Xianqun Fan

Journal Article

How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Journal Article

Intratumoral Bacteria Dysbiosis Is Associated with Human Papillary Thyroid Cancer and Correlated with

Shuang Yu, Yanqiang Ding, Xuejie Wang, Siu Kin Ng, Siting Cao, Weixin Liu, Zhuming Guo, Yubin Xie, Shubin Hong, Lixia Xu, Xiaoxing Li, Jie Li, Weiming Lv, Sui Peng, Yanbing Li, Joseph J.Y. Sung, Jun Yu, Haipeng Xiao

Journal Article

Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern

Lizhe Ai, Yaqin Yu, Xiaoli Liu, Chong Wang, Jieping Shi, Hui Sun, Qiong Yu

Journal Article

Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Journal Article

RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Journal Article

RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Yinglin JI, Mingyang XU, Aide WANG

Journal Article

Analyses of levels of thyroid hormones and its receptor expression in puerperants and newborns from an

JU Ying, CHEN Lan, JIANG Qi, YANG Kedi, CHEN Xuemin, XU Guojian, LI Liping

Journal Article

mesenchymal stem cells promotes the expression of tumor-suppressive FAT1 and inhibits stemness maintenance in thyroid

Journal Article

The study of ovary development and steroid hormone changes in Alosa sapidissima

Hong Lei,Li Zhaoxin,Chen Chao,Guo Zhenglong,Wang Weifang,Lei Jilin

Journal Article

Progress and challenges in RET-targeted cancer therapy

Journal Article