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《医学前沿(英文)》 >> 2007年 第1卷 第2期 doi: 10.1007/s11684-007-0043-1

Relationship between selenium concentration in child hair and the distribution of Kashin-Beck Disease in Tibet, China

1.Environmental School, Beijing Normal University, Beijing 100875, China; Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China; 2.Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China; 3.Tibet Municipality Centers for Disease Control and Prevention, Lhasa 850000, China;

发布日期: 2007-06-05

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摘要

The focus of this study is to determine the relationship between selenium (Se) concentrations in child hair and the distribution of Kashin-Beck disease (KBD) in Tibet. The hair of children in typical KBD-affected areas and non-disease areas was collected, and its Se concentrations were measured by atomic fluorescent spectrometry. The Se concentrations in child hair were (0.13±0.04) and (0.18±0.07) µg/g respectively in KBD areas and non-disease areas respectively, which are significantly different. In areas supplemented with Se in Tibet, the Se concentration of hair in KBD- affected areas was higher than that in non-diseased areas, being (0.28±0.03) and (0.18±0.04) µg/g respectively. There is a close relationship between the Se concentrations in hair and KBD distribution. Se supplement increase the Se concentrations in the human body. Appropriate Se supplementation is important to prevent KBD in Tibet.

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