Iron oxide nanoparticle-based theranostics for cancer imaging and therapy

2014年第8卷第3期

摘要

关键词

相关研究

回顶部

《化学科学与工程前沿（英文）》 >> 2014年第8卷第3期 doi: 10.1007/s11705-014-1425-y

Iron oxide nanoparticle-based theranostics for cancer imaging and therapy

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.2. School of Pharmacy, Fudan University, Shanghai 200433, China

发布日期： 2014-10-11

HTML23 PDF 1 收藏 0

摘要

Theranostic platform, which is equipped with both diagnostic and therapeutic functions, is a promising approach in cancer treatment. From various nanotheranostics studied, iron oxide nanoparticles have advantages since IONPs have good biocompatibility and spatial imaging capability. This review is focused on the IONP-based nanotheranostics for cancer imaging and treatment. The most recent progress for applications of IONP nanotheranostics is summarized, which includes IONP-based diagnosis, magnetic resonance imaging (MRI), multimodal imaging, chemotherapy, hyperthermal therapy, photodynamic therapy, and gene delivery. Future perspectives and challenges are also outlined for the potential development of IONP based theranostics in clinical use.

关键词

theranostics ; iron oxide nanoparticles ; MRI ; drug delivery ; photothermal therapy ; photodynamic therapy