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Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational
《医学前沿(英文)》 2022年 第16卷 第4期 页码 651-658 doi: 10.1007/s11684-021-0859-0
关键词: acute coronary syndrome (ACS) throat discomfort (TD) throat pain cardiology departments non-cardiologic physicians
Acupuncture is ineffective for chronic low back pain? A critical analysis and rethinking
Xuqiang Wei, Baoyan Liu
《医学前沿(英文)》 2021年 第15卷 第5期 页码 767-775 doi: 10.1007/s11684-020-0785-6
关键词: chronic low back pain sham acupuncture acupuncture methodology therapeutic evaluation
Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a
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《医学前沿(英文)》 2015年 第9卷 第4期 页码 496-507 doi: 10.1007/s11684-015-0414-y
Perioperative parecoxib administration reduces postoperative pain, opioid consumption, and adverse events in adult patients. However, the efficacy and safety of parecoxib in children remain unclear. This meta-analysis included related published studies to address this concern. Eight databases in the literature until February 2015 were systematically explored to identify randomized controlled trials (RCTs) comparing perioperative parecoxib administration and placebo/standard treatments for acute postoperative pain in children. Primary outcomes were postoperative pain scores and adverse events. The Face, Legs, Activity, Crying, Consolability scale was used to score pain in children younger than 6 years, whereas the Visual Analog Scale was used in children older than 6 years. Secondary outcomes were sedation scores (measured using the Ramsay scale), agitation scores (measured using the Sedation-Agitation Scale), and opioid consumption. The methodological quality of RCTs was independently assessed in accordance with the “Risk of bias” of Cochrane Collaboration. Data were analyzed using Review Manager 5.2. Twelve RCTs involving 994 patients met the inclusion criteria. Compared with children who received placebo treatment, those who received parecoxib demonstrated lower early (2 h) and later (12 h) postoperative pain scores; lower incidence rates of postoperative nausea, vomiting, and agitation; higher early (1 h) postoperative sedation scores; and lower agitation scores. Similarly, children who received parecoxib had lower early (2 h) and later (12 h) postoperative pain scores, lower incidence rates of postoperative nausea and vomiting, and lower early (1 h) postoperative sedation scores compared with those who received standard treatments; however, these children showed no significant difference in agitation scores. Unfortunately, data on the effect of parecoxib on opioid consumption were insufficient. Overall, these results suggested that perioperative parecoxib administration was associated with less acute postoperative pain and fewer adverse events compared with placebo or standard treatments. Parecoxib administration also resulted in less emergence agitation compared with placebo treatment and less excessive sedation concern compared with standard treatments. However, the long-term effects, effects on opioid consumption, and patient satisfaction of parecoxib administration warrant further investigation.
关键词: NSAID cyclooxygenase 2 inhibitor child pain postoperative opioid placebo
Factors related to compliance with oral analgesic treatment of inpatients with chronic pain
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《医学前沿(英文)》 2015年 第9卷 第3期 页码 374-379 doi: 10.1007/s11684-015-0411-1
This study aimed to determine the relationship between the different factors of analgesic therapy and the compliance of chronic pain inpatients. We prospectively investigated 100 consecutive inpatients with non-cancer chronic pain who were hospitalized to receive oral analgesic treatment in the Pain Department of West China Hospital from May 2013 to October 2013. Patients who completed the treatment plan were recorded as good compliance, whereas patients who partly completed or even refused the treatment were recorded as moderate or non-compliance, respectively. A total of 73 (73.7%), 17 (17.1%), and 9 (9.2%) patients showed good, moderate, and non-compliance, respectively. Univariate analyses showed significantly better compliance among farmers, patients educated in college or above, with family income of<3000 CNY, and with severe or moderate pain than those employed and unemployed (P=0.02), patients educated below college (P=0.013), with family income of≥3000 CNY (P=0.025), and with mild pain (P<0.001), respectively. Logistic regression analysis showed that the family income of≥3000 CNY (OR: 2.50, 95%CI: 1.65–4.51, P=0.021) and mild pain (OR: 1.27, 95%CI: 1.03–3.31, P=0.016) were associated with moderate or non-compliance with oral analgesic treatment. In conclusion, the low compliance with oral treatment of analgesics was found in Chinese inpatients with chronic pain and compliance was negatively associated with family income and degree of pain of patients.
Mechanism of acupuncture regulating visceral sensation and mobility
Peijing Rong, Bing Zhu, Yuqing Li, Xinyan Gao, Hui Ben, Yanhua Li, Liang Li, Wei He, Rupeng Liu, Lingling Yu
《医学前沿(英文)》 2011年 第5卷 第2期 页码 151-156 doi: 10.1007/s11684-011-0129-7
关键词: acupuncture somite visceral pain somato-visceral connection meridian
Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin
《工程(英文)》 2017年 第3卷 第1期 页码 16-27 doi: 10.1016/J.ENG.2017.01.003
膝关节骨性关节炎(OA) 是世界上常见的关节炎,其发病率年上升。不断上涨的治疗费用给患者带来了经济负担。膝关节OA 治疗的两个早期干预目标是减轻膝关节的疼痛和关节软骨的损害。目前用于治疗膝关节OA 的方法虽取得了一定疗效,但仍没有种方法可达到全膝关节置换术(TKA) 的治疗效果TKA 主要应用于治疗末期膝关节OA,其缺点是有手术侵入性和手术费用昂贵。因而,应该重视创新性的再生术,以推迟甚至消除患者对TKA 的需求一些基于生物材料和细胞的疗法目前正处于发展阶段,并已在临床前和临床研究方面取得了初步进展单独或联合应用先进的生物材料和干细胞治疗膝关节OA 可减轻疼痛,使损害的关节软骨再生。在此综述中,我们讨论了膝关节OA 疼痛和软骨损害的发病机制,并探讨了该病的新治疗策略及其局限
标题 作者 时间 类型 操作
Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational
期刊论文
Acupuncture is ineffective for chronic low back pain? A critical analysis and rethinking
Xuqiang Wei, Baoyan Liu
期刊论文
Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a
null
期刊论文
Factors related to compliance with oral analgesic treatment of inpatients with chronic pain
null
期刊论文
Mechanism of acupuncture regulating visceral sensation and mobility
Peijing Rong, Bing Zhu, Yuqing Li, Xinyan Gao, Hui Ben, Yanhua Li, Liang Li, Wei He, Rupeng Liu, Lingling Yu
期刊论文