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《医学前沿(英文)》 2022年 第16卷 第1期 页码 139-149 doi: 10.1007/s11684-021-0835-8
关键词: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
《医学前沿(英文)》 2021年 第15卷 第4期 页码 608-620 doi: 10.1007/s11684-021-0836-7
关键词: t(8 21)(q22 q22) AML CD34+CD117dim/ CD34+CD117bri cell population gene expression prognosis
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
《环境科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 226-238 doi: 10.1007/s11783-013-0582-4
关键词:
cadmium (Cd)
low-Cd cultivar
pakchoi (
《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1687-z
● Organic solvent extracted fewer Cd/Pb in rapeseed oil than physical pressing.
关键词: Rapeseed oil Oil extraction technologies Human health risk assessment Cd/Pb-contaminated farmland Substitute planting
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 108-112 doi: 10.1007/s11684-009-0015-8
关键词: celecoxib CD437 melanoma A375 cell apoptosis cycle arrest
SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping
《环境科学与工程前沿(英文)》 2007年 第1卷 第1期 页码 107-113 doi: 10.1007/s11783-007-0020-6
《医学前沿(英文)》 doi: 10.1007/s11684-023-1010-1
关键词: exosomes induce activation impair function CD19 exosomal CD19 antigen
Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3
WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng
《医学前沿(英文)》 2008年 第2卷 第4期 页码 366-369 doi: 10.1007/s11684-008-0070-6
CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer
《医学前沿(英文)》 2023年 第17卷 第1期 页码 105-118 doi: 10.1007/s11684-022-0934-1
关键词: osimertinib anti-CD47 antibody combination strategy ADCP EGFR
Xia Hou, Liping Huang, Peng Zhou, Hua Xue, Ning Li
《环境科学与工程前沿(英文)》 2018年 第12卷 第4期 doi: 10.1007/s11783-018-1057-4
Cell membrane of indigenous Cd-tolerant EAB harbored more cadmium than chromium. Indigenous Cd-tolerant EAB cytoplasm located more chromium than cadmium. Simultaneously quantitatively imaging Cd(II) and Cr(III) ions in EAB was achieved. Current accelerated the harboring of cadmium in EAB at an initial 2 h. Current directed the accumulation of more chromium in EAB over time.
关键词: Microbial electrolysis cell Electrochemically active bacteria Cd-tolerant bacteria Cd(II) and Cr(VI) Fluorescence probe
null
《医学前沿(英文)》 2011年 第5卷 第1期 页码 101-105 doi: 10.1007/s11684-011-0111-4
It has been demonstrated that β-elemene could protect against carbon tetrachloride (CCl4)-induced liver fibrosis in our laboratory work, and the aim of this paper is to reveal the protective mechanisms of β-elemene. The hepatic fibrosis experimental model was induced by the hypodermical injection of CCl4 in Wistar male rats. β-elemene was intraperitoneally administered into rats for 8 weeks (0.1 mL/100 g bodyweight per day), and plasma endotoxin content was assayed by biochemistry. The serum TNF-α level was detected using radioactive immunity. CD14 expression in rat livers was measured by immunohistochemistry and Western blot. The results showed that β-elemene can downregulate the levels of plasma endotoxins, serum TNF-α, and hepatic CD14 expression in rats with liver fibrosis. β-elemene plays an important role in downregulating the lipopolysaccharide signal transduction pathway, a significant pathway in hepatic fibrosis development.
LU Ling, ZHANG Feng, PU Liyong, YAO Aihua, YU Yue, SUN Beicheng, LI Guoqiang, WANG Xuehao
《医学前沿(英文)》 2007年 第1卷 第4期 页码 373-376 doi: 10.1007/s11684-007-0072-9
外泌体CD44与整合素α6β4结合激活宿主细胞重塑肿瘤微环境促进胰腺癌恶性转移 Article
牟为, 许亚婕, 顾鹏飞, 王文斌, 李井泉, 葛阳, 王慧
《工程(英文)》 2021年 第7卷 第10期 页码 1415-1425 doi: 10.1016/j.eng.2020.08.013
Effects of organic acids on Cd adsorption and desorption by two anthropic soils
Jingui WANG, Jialong LV, Yaolong FU
《环境科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 19-30 doi: 10.1007/s11783-012-0424-9
关键词: adsorption desorption cadmium organic acids temperature anthropic soil
null
《医学前沿(英文)》 2016年 第10卷 第2期 页码 204-211 doi: 10.1007/s11684-016-0443-1
CD176 (Thomsen-Friedenreich antigen) is a tumor-associated carbohydrate epitope (glycotope) functionally involved in blood spread and liver metastasis of cancer cells by mediating the adhesion of cancer cells to endothelial cells and hepatocytes, respectively. CD176 could be a promising target for antitumor immunotherapy. We applied B lymphocytes obtained from mice immunized with CD176 antigen and constructed a phage display library. A positive clone of CD176 single-chain variable antibody fragment (scFv) was successfully screened from this library. The CD176 scFv was expressed in Escherichia coli and purified. The purified scFv can bind to the natural CD176 expressed on the surface of cancer cells. Furthermore, the CD176 scFv inhibits the adhesion of CD176+ cancer cells to endothelial cells and hepatocytes. This CD176 scFv provides a basis for future development of recombinant CD176-specific antibodies that can be used in therapeutic application.
关键词: CD176 Thomsen-Friedenreich antigen scFv cancer therapy adhesion metastasis
标题 作者 时间 类型 操作
Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific
期刊论文
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
期刊论文
Comparisons in subcellular and biochemical behaviors of cadmium between low-Cd and high-Cd accumulation
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
期刊论文
Cultivars and oil extraction techniques affect Cd/Pb contents and health risks in oil of rapeseed grownon Cd/Pb-contaminated farmland
期刊论文
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
期刊论文
Growth responses of the newly-discovered Cd-hyperaccumulator Rorippa globosa and its accumulation characteristicsof Cd and As under joint stress of Cd and As
SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping
期刊论文
Tumor-derived exosomes induce initial activation by exosomal CD19 antigen but impair the function ofCD19-specific CAR T-cells via TGF-β signaling
期刊论文
Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3
WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng
期刊论文
Response of indigenous Cd-tolerant electrochemically active bacteria in MECs toward exotic Cr(VI) based
Xia Hou, Liping Huang, Peng Zhou, Hua Xue, Ning Li
期刊论文
Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14
null
期刊论文
Biological features of intrahepatic CD4+CD25+ T cells in the naturally tolerance of rat liver transplantation
LU Ling, ZHANG Feng, PU Liyong, YAO Aihua, YU Yue, SUN Beicheng, LI Guoqiang, WANG Xuehao
期刊论文
Effects of organic acids on Cd adsorption and desorption by two anthropic soils
Jingui WANG, Jialong LV, Yaolong FU
期刊论文