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Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng
《医学前沿(英文)》 2018年 第12卷 第5期 页码 580-585 doi: 10.1007/s11684-017-0585-9
This study aimed to evaluate the effects of thyroid hormone supplementation on growth rate of children with idiopathic short stature (ISS) and low-normal serum free thyroxine FT4 who were receiving growth hormone therapy. We selected 64 prepubertal children with FT4 levels in the lowest third of the normal range as the lower FT4 group, and these children were divided randomly into two subgroups: L-thyroxine (L-T4)-treated subgroup was treated with L-T4 (0.5–3.0 g/(kg·d)) from the beginning of the study, and the non-L-T4-treated subgroup received placebo. We also selected 39 ISS children with FT4 in the upper two-thirds of the normal range as the higher FT4 group. During the first year, the lower FT4 group featured lower FT3, FT4, thyroid stimulating hormone (TSH), and insulin-like growth factor-I standard deviation score (IGF-I SDS) and significantly lower height velocity (HV) compared with the higher FT4 group. However, in the lower FT4 group, the L-T4-treated subgroup presented higher FT4, FT3, TSH, and IGF-I SDS concentrations and significantly higher HV compared with children in the non-L-T4-treated subgroup. In children with ISS, the negative effect of thyroid hormone deficiency on growth rate should be considered when FT4 level lies in the low-normal range prior to recombinant human growth hormone treatment.
关键词: therapeutic idiopathic short-stature children free T4 the first year recombinant human growth hormone
Serum erythropoietin and transferrin in children with idiopathic nephrotic syndrome
LU Hongzhu, LIU Dan, ZHANG Wanming, YUAN Yuesha, KUANG Hongyan, WANG Lin, FAN Qihong
《医学前沿(英文)》 2008年 第2卷 第3期 页码 286-289 doi: 10.1007/s11684-008-0054-6
《环境科学与工程前沿(英文)》 2023年 第17卷 第9期 doi: 10.1007/s11783-023-1705-1
● A study assessing the temperature-injury relationship was conducted among students.
关键词: Ambient temperature Fall Road traffic injury Student China
Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty
null
《医学前沿(英文)》 2018年 第12卷 第2期 页码 174-181 doi: 10.1007/s11684-017-0544-5
The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) has been recently documented. In this study, 280 girls diagnosed with ICPP and 188 normal puberty control girls of similar ages were enrolled and retrospectively studied. The ICPP group had significantly lower serum 25-hydroxyvitamin D (25[OH]D) levels than the control group. Furthermore, a nonlinear relationship was found between serum 25[OH]D and ICPP, and a cut-off point for serum 25[OH]D was found at 31.8 ng/ml for ICPP with and without adjusting the different confounding factors. Girls with serum 25[OH]D≥31.8 ng/ml had a lower odds ratio (unadjusted: OR 0.36, 95% CI 0.15 to 0.83, <0.05; height and weight adjusted: OR 0.44, 95% CI 0.18 to 1.08, = 0.072; BMI adjusted: OR 0.36, 95% CI 0.16 to 0.84, <0.05). The ICPP subjects with 25[OH]D deficiency had a higher body mass index (BMI) than the subjects from the two other subgroups. Correlation analysis showed that vitamin D level is correlated with BMI and some metabolic parameters in the ICPP group. Our study suggested that vitamin D status may be associated with ICPP risk and may have a threshold effect on ICPP.
关键词: idiopathic central precocious puberty threshold effects vitamin D status
《医学前沿(英文)》 2023年 第17卷 第3期 页码 518-526 doi: 10.1007/s11684-022-0958-6
关键词: acute lymphoblastic leukemia child venous thromboembolism epidemiology clinical characteristic risk factor
null
《医学前沿(英文)》 2013年 第7卷 第2期 页码 264-269 doi: 10.1007/s11684-013-0259-1
The effect of the severity of appendiceal inflammation on post-operative stay in children following appendicectomy has shown conflicting results. This study was conducted to determine the association between the severity of appendiceal inflammation and post-operative stay amongst children undergoing open appendicectomy. A retrospective cohort study was conducted at a District General Hospital for two years. A total of 204 patients were included in the study with an age range between 3 and 16 years. Females were 54.9% while the rest were male. Mean age was 12.5±3 years. The association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariable Cox Proportional hazards model. Mean post-operative stay was 2.32 days (95% CI 2.14–2.51). Macroscopically perforated appendix, histological inflammation and post-operative complications were significantly associated with post-operative stay on univariable analysis (P<0.05). Whereas, the multivariable analysis showed that the post-operative stay was significantly prolonged only in case of either perforated appendix or post-operative complications while it remained unaffected by the histological inflammation.
关键词: appendiceal inflammation post-operative stay paediatrics
Epidemic obesity in children and adolescents: risk factors and prevention
Eun Young Lee, Kun-Ho Yoon
《医学前沿(英文)》 2018年 第12卷 第6期 页码 658-666 doi: 10.1007/s11684-018-0640-1
关键词: obesity children adolescents epidemiology risk factor prevention
Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a
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《医学前沿(英文)》 2015年 第9卷 第4期 页码 496-507 doi: 10.1007/s11684-015-0414-y
Perioperative parecoxib administration reduces postoperative pain, opioid consumption, and adverse events in adult patients. However, the efficacy and safety of parecoxib in children remain unclear. This meta-analysis included related published studies to address this concern. Eight databases in the literature until February 2015 were systematically explored to identify randomized controlled trials (RCTs) comparing perioperative parecoxib administration and placebo/standard treatments for acute postoperative pain in children. Primary outcomes were postoperative pain scores and adverse events. The Face, Legs, Activity, Crying, Consolability scale was used to score pain in children younger than 6 years, whereas the Visual Analog Scale was used in children older than 6 years. Secondary outcomes were sedation scores (measured using the Ramsay scale), agitation scores (measured using the Sedation-Agitation Scale), and opioid consumption. The methodological quality of RCTs was independently assessed in accordance with the “Risk of bias” of Cochrane Collaboration. Data were analyzed using Review Manager 5.2. Twelve RCTs involving 994 patients met the inclusion criteria. Compared with children who received placebo treatment, those who received parecoxib demonstrated lower early (2 h) and later (12 h) postoperative pain scores; lower incidence rates of postoperative nausea, vomiting, and agitation; higher early (1 h) postoperative sedation scores; and lower agitation scores. Similarly, children who received parecoxib had lower early (2 h) and later (12 h) postoperative pain scores, lower incidence rates of postoperative nausea and vomiting, and lower early (1 h) postoperative sedation scores compared with those who received standard treatments; however, these children showed no significant difference in agitation scores. Unfortunately, data on the effect of parecoxib on opioid consumption were insufficient. Overall, these results suggested that perioperative parecoxib administration was associated with less acute postoperative pain and fewer adverse events compared with placebo or standard treatments. Parecoxib administration also resulted in less emergence agitation compared with placebo treatment and less excessive sedation concern compared with standard treatments. However, the long-term effects, effects on opioid consumption, and patient satisfaction of parecoxib administration warrant further investigation.
关键词: NSAID cyclooxygenase 2 inhibitor child pain postoperative opioid placebo
Yuan-zhang Liu: a Short Biography
Anon
《工程管理前沿(英文)》 2014年 第1卷 第1期 页码 113-114 doi: 10.1530/J-FEM-2014016
Fibrous dysplasia involving the calvarium in children?
Chunquan CAI, Qian LI, Qingjiang ZHANG, Changhong SHEN
《医学前沿(英文)》 2009年 第3卷 第2期 页码 211-215 doi: 10.1007/s11684-009-0024-7
Shou-rong Zhang: a Short Biography
Anon.
《工程管理前沿(英文)》 2014年 第1卷 第2期 页码 225-226 doi: 10.15302/J-FEM-2014030
Association of metabolic syndrome with arterial compliance in children and adolescents
ZHANG Li, MI Jie, LI Ming, JIANG Benyu
《医学前沿(英文)》 2007年 第1卷 第1期 页码 68-73 doi: 10.1007/s11684-007-0014-6
关键词: compliance assessment correlation analysis cardiovascular clustering HOMA-IR
A hybrid Wavelet-CNN-LSTM deep learning model for short-term urban water demand forecasting
《环境科学与工程前沿(英文)》 2023年 第17卷 第2期 doi: 10.1007/s11783-023-1622-3
● A novel deep learning framework for short-term water demand forecasting.
关键词: Short-term water demand forecasting Long-short term memory neural network Convolutional Neural Network Wavelet multi-resolution analysis Data-driven models
Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19
Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li
《医学前沿(英文)》 2020年 第14卷 第6期 页码 776-785 doi: 10.1007/s11684-020-0820-7
关键词: coronavirus disease 2019 pediatrics emergency retrospective investigation severe acute respiratory syndrome coronavirus 2
Mingtao RUN, Hongzan SONG, Yanping HAO
《化学科学与工程前沿(英文)》 2009年 第3卷 第3期 页码 255-264 doi: 10.1007/s11705-009-0008-9
关键词: poly(trimethylene terephthalate) short carbon fiber banded spherulites crack
标题 作者 时间 类型 操作
Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children during
Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng
期刊论文
Serum erythropoietin and transferrin in children with idiopathic nephrotic syndrome
LU Hongzhu, LIU Dan, ZHANG Wanming, YUAN Yuesha, KUANG Hongyan, WANG Lin, FAN Qihong
期刊论文
Evaluating the short-term effect of ambient temperature on non-fatal outdoor falls and road traffic injuriesamong children and adolescents in China: a time-stratified case-crossover study
期刊论文
Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the ChineseChildren’s Cancer Group-ALL-2015
期刊论文
Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth
null
期刊论文
Epidemic obesity in children and adolescents: risk factors and prevention
Eun Young Lee, Kun-Ho Yoon
期刊论文
Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a
null
期刊论文
Fibrous dysplasia involving the calvarium in children?
Chunquan CAI, Qian LI, Qingjiang ZHANG, Changhong SHEN
期刊论文
Association of metabolic syndrome with arterial compliance in children and adolescents
ZHANG Li, MI Jie, LI Ming, JIANG Benyu
期刊论文
Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19
Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li
期刊论文