检索范围:
排序: 展示方式:
null
《医学前沿(英文)》 2017年 第11卷 第1期 页码 97-109 doi: 10.1007/s11684-016-0496-1
As muscle activity during growth is considerably important for mandible quality and morphology, reducing dietary loading directly influences the development and metabolic activity of mandibular condylar cartilage (MCC). However, an overall investigation of changes in the protein composition of MCC has not been fully described in literature. To study the protein expression and putative signaling in vivo, we evaluated the structural changes of MCC and differentially expressed proteins induced by reducing functional loading in rat MCC at developmental stages. Isobaric tag for relative and absolute quantitation-based 2D nano-high performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionization time-of-flight/ time-of-flight (MALDI-TOF/TOF) technologies were used. Global protein profiling, KEGG and PANTHER pathways, and functional categories were analyzed. Consequently, histological and tartrate-resistant acid phosphatase staining indicated the altered histological structure of condylar cartilage and increased bone remodeling activity in hard-diet group. A total of 805 differentially expressed proteins were then identified. GO analysis revealed a significant number of proteins involved in the metabolic process, cellular process, biological regulation, localization, developmental process, and response to stimulus. KEGG pathway analysis also suggested that these proteins participated in various signaling pathways, including calcium signaling pathway, gap junction, ErbB signaling pathway, and mitogen-activated protein kinase signaling pathway. Collagen types I and II were further validated by immunohistochemical staining and Western blot analysis. Taken together, the present study provides an insight into the molecular mechanism of regulating condylar growth and remodeling induced by reducing dietary loading at the protein level.
关键词: condylar cartilage mechanical loading proteomic analysis iTRAQ bioinformatics analysis
Shujuan ZHANG,Guoqi SONG,Yulian LI,Jie GAO,Jiao WANG,Guiju CHEN,Haosheng LI,Genying LI,Zhendong ZHAO
《农业科学与工程前沿(英文)》 2014年 第1卷 第1期 页码 37-45 doi: 10.15302/J-FASE-2014008
关键词: common wheat spring radiation frost proteomic analysis 2-DE MALDI-TOF-TOF MS
Decomposition analysis applied to energy and emissions: A literature review
《工程管理前沿(英文)》 页码 625-639 doi: 10.1007/s42524-023-0270-4
关键词: index decomposition analysis structural decomposition analysis production decomposition analysis energy CO2 emissions
B. VIDHYA,K. N. SRINIVAS
《能源前沿(英文)》 2016年 第10卷 第4期 页码 424-440 doi: 10.1007/s11708-016-0423-9
关键词: flux reversal generator air velocity computation fluid dynamics thermal analysis vibration analysis finite element analysis
Review of sentiment analysis: An emotional product development view
《工程管理前沿(英文)》 页码 592-609 doi: 10.1007/s42524-022-0227-z
关键词: sentiment analysis emotion product development Kansei Engineering
Jack up reliability analysis: An overview
Ahmad IDRIS, Indra Sati Hamonangan HARAHAP, Montasir Osman Ahmed ALI
《结构与土木工程前沿(英文)》 2018年 第12卷 第4期 页码 504-514 doi: 10.1007/s11709-017-0443-5
关键词: jack up reliability analysis uncertainty analysis review of jack up
Systems biomedical analysis of Schistosoma japonicum
Ze-Guang HAN MD,
《医学前沿(英文)》 2010年 第4卷 第2期 页码 157-165 doi: 10.1007/s11684-010-0034-5
Pengxing YI,Peng HUANG,Tielin SHI
《机械工程前沿(英文)》 2016年 第11卷 第4期 页码 388-402 doi: 10.1007/s11465-016-0404-z
Wind turbine gearbox (WTG), which functions as an accelerator, ensures the performance and service life of wind turbine systems. This paper examines the distinctive modal properties of WTGs through finite element (FE) and experimental modal analyses. The study is performed in two parts. First, a whole system model is developed to investigate the first 10 modal frequencies and mode shapes of WTG using flexible multi-body modeling techniques. Given the complex structure and operating conditions of WTG, this study applies spring elements to the model and quantifies how the bearings and gear pair interactions affect the dynamic characteristics of WTGs. Second, the FE modal results are validated through experimental modal analyses of a 1.5 WM WTG using the frequency response function method of single point excitation and multi-point response. The natural frequencies from the FE and experimental modal analyses show favorable agreement and reveal that the characteristic frequency of the studied gearbox avoids its eigen-frequency very well.
关键词: wind turbine gearbox modal analysis finite element analysis modal frequency bearing equivalence
Isogeometric analysis of coupled thermo-elastodynamic problems under cyclic thermal shock
Asghar AMANI DASHLEJEH
《结构与土木工程前沿(英文)》 2019年 第13卷 第2期 页码 397-405 doi: 10.1007/s11709-018-0473-7
关键词: isogeometric analysis coupled thermo-elastodynamic dynamic analysis generalized newmark cyclic thermal shock
A dimensional analysis on asphalt binder fracture and fatigue cracking
Qian ZHAO, Zhoujing YE
《结构与土木工程前沿(英文)》 2018年 第12卷 第2期 页码 201-206 doi: 10.1007/s11709-017-0402-1
A frequency error estimation for isogeometric analysis of Kirchhoff–Love cylindrical shells
《结构与土木工程前沿(英文)》 doi: 10.1007/s11709-023-0006-x
关键词: isogeometric analysis Kirchhoff–Love cylindrical shell free vibration frequency error convergence
Structural dynamic analysis of the orbiting scroll wrap in the scroll compressor
Yicai LIU, Yubo XIA, Peng YAN, Yinbin LI, Haibo XIE
《能源前沿(英文)》 2013年 第7卷 第1期 页码 19-25 doi: 10.1007/s11708-012-0223-9
关键词: scroll compressor orbiting scroll wrap model analysis harmonic analysis
Numerical analysis of nonlinear dynamic behavior of earth dams
Babak EBRAHIMIAN
《结构与土木工程前沿(英文)》 2011年 第5卷 第1期 页码 24-40 doi: 10.1007/s11709-010-0082-6
关键词: earth dam numerical nonlinear response dynamic analysis earthquake dam height
Qing-hua He,Ge Wang
《工程管理前沿(英文)》 2015年 第2卷 第2期 页码 141-147 doi: 10.15302/J-FEM-2015023
Reliability analysis of urban gas transmission and distribution system based on FMEA and correlation
Su LI,Weiguo ZHOU
《能源前沿(英文)》 2014年 第8卷 第4期 页码 443-448 doi: 10.1007/s11708-014-0336-4
关键词: gas transmission and distribution system risk evaluation reliability analysis failure mode and effects analysis (FMEA) correlation operator
标题 作者 时间 类型 操作
iTRAQ-based quantitative proteomic analysis on differentially expressed proteins of rat mandibular condylar
null
期刊论文
Comparative proteomic analysis of cold responsive proteins in two wheat cultivars with different tolerance
Shujuan ZHANG,Guoqi SONG,Yulian LI,Jie GAO,Jiao WANG,Guiju CHEN,Haosheng LI,Genying LI,Zhendong ZHAO
期刊论文
Flow, thermal, and vibration analysis using three dimensional finite element analysis for a flux reversal
B. VIDHYA,K. N. SRINIVAS
期刊论文
Jack up reliability analysis: An overview
Ahmad IDRIS, Indra Sati Hamonangan HARAHAP, Montasir Osman Ahmed ALI
期刊论文
Numerical analysis and experimental investigation of modal properties for the gearbox in wind turbine
Pengxing YI,Peng HUANG,Tielin SHI
期刊论文
Isogeometric analysis of coupled thermo-elastodynamic problems under cyclic thermal shock
Asghar AMANI DASHLEJEH
期刊论文
Structural dynamic analysis of the orbiting scroll wrap in the scroll compressor
Yicai LIU, Yubo XIA, Peng YAN, Yinbin LI, Haibo XIE
期刊论文
Hotspots Evolution and Frontier Analysis of Lean Construction Research—Integrated Scientometric Analysis
Qing-hua He,Ge Wang
期刊论文