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Frontiers of Environmental Science & Engineering >> 2019, Volume 13, Issue 3 doi: 10.1007/s11783-019-1124-5

Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination

1. Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China
2. University of Chinese Academy of Science, Beijing 100049, China
3. Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA 24060, USA

Available online: 2019-06-06

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Abstract

Extracellular DNA structure damaged by chlorination was characterized.

Integrity of extracellular ARG genetic information after chlorination was determined.

Typical chlorine doses will likely effectively diminish extracellular DNA and ARGs.

Plasmid DNA/ARGs were less readily broken down than genomic DNA.

The Bioanalyzer methodology effectively documented damage incurred to DNA.

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