Search scope:
排序: Display mode:
Development Strategy of Integrative Pharmacy
Zhang Yong, Zhao Yixiu, Yang Baofeng
Strategic Study of CAE 2021, Volume 23, Issue 1, Pages 185-192 doi: 10.15302/J-SSCAE-2021.01.022
Keywords: integrative pharmacy integrative drugs new drug development drug evaluation clinical medication guidance
Holistic integrative medicine: toward a new era of medical advancement
Daiming Fan
Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 152-159 doi: 10.1007/s11684-017-0499-6
Keywords: holistic integrative medicine precision medicine general practice medicine
ROLE OF NITROGEN SENSING AND ITS INTEGRATIVE SIGNALING PATHWAYS IN SHAPING ROOT SYSTEM ARCHITECTURE
Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 3, Pages 316-332 doi: 10.15302/J-FASE-2022441
● The Green Revolution broadened the trade-off between yield and nitrogen-use efficiency.
Keywords: Nitrogen root system architecture phytohormone crosstalk nitrogen-use efficiency breeding strategy
Seiya MAKI, Shuichi ASHINA, Minoru FUJII, Tsuyoshi FUJITA, Norio YABE, Kenji UCHIDA, Gito GINTING, Rizaldi BOER, Remi CHANDRAN
Frontiers in Energy 2018, Volume 12, Issue 3, Pages 426-439 doi: 10.1007/s11708-018-0560-4
The Paris Agreement calls for maintaining a global temperature less than 2°C above the pre-industrial level and pursuing efforts to limit the temperature increase even further to 1.5°C. To realize this objective and promote a low-carbon society, and because energy production and use is the largest source of global greenhouse-gas (GHG) emissions, it is important to efficiently manage energy demand and supply systems. This, in turn, requires theoretical and practical research and innovation in smart energy monitoring technologies, the identification of appropriate methods for detailed time-series analysis, and the application of these technologies at urban and national scales. Further, because developing countries contribute increasing shares of domestic energy consumption, it is important to consider the application of such innovations in these areas. Motivated by the mandates set out in global agreements on climate change and low-carbon societies, this paper focuses on the development of a smart energy monitoring system (SEMS) and its deployment in households and public and commercial sectors in Bogor, Indonesia. An electricity demand prediction model is developed for each device using the Auto-Regression eXogenous model. The real-time SEMS data and time-series clustering to explore similarities in electricity consumption patterns between monitored units, such as residential, public, and commercial buildings, in Bogor is, then, used. These clusters are evaluated using peak demand and Ramadan term characteristics. The resulting energy-prediction models can be used for low-carbon planning.
Keywords: electricity monitoring electricity demand prediction multiple-variable time-series modeling time-series cluster analysis Indonesia
Development Strategy of Chinese and Western Integrative Medicine Under New Circumstances
Wang Conghui, Feng Zhe, Yin Zhiwei, Li Shuang, Chen Xiangmei
Strategic Study of CAE 2021, Volume 23, Issue 2, Pages 169-174 doi: 10.15302/J-SSCAE-2021.02.016
Keywords: Chinese and western integrative medicine evidence-based medicine evaluation system talent training
The Overall Development Strategy Research of “Internet Plus” Action Plan
Chen Zuoning,Li Bohu,Chai Xudong,Hou Baocun,Liu Yang,Chen Lei and Cheng Lin
Strategic Study of CAE 2018, Volume 20, Issue 2, Pages 1-8 doi: 10.15302/J-SSCAE-2018.02.001
Keywords: Internet Plus integrative development development strategy
Zhengyi Jiang, Zeyu Sun, Xiaoxi Ouyang, Yalei Zhao, Menghao Zhou, Baohong Wang, Qirui Li, Linxiao Fan, Sainan Zhang, Lanjuan Li
Engineering 2020, Volume 6, Issue 11, Pages 1302-1314 doi: 10.1016/j.eng.2020.02.011
Primary hepatocytes (PHCs) are widely used in various fields, but the progressive deterioration of liver-specific features in vitro significantly limits their application. While the transcriptional regulation and whole cell proteome (WCP) of PHCs have been extensively studied, only a small number of studies have addressed the role of posttranslational modifications in this process. To elucidate the underlying mechanisms that induce dedifferentiation, we carried out parallel quantifications of the transcriptome, WCP, ubiquitinome, and phosphoproteome of rat PHCs after 0, 6, 12, 24, and 48 h of in vitro culture. Our data constitute a detailed proteomic analysis of dedifferentiated PHCs including 2196 proteins, 2056 ubiquitinated sites, and 4932 phosphorylated peptides. We revealed a low correlation between the transcriptome and WCP during dedifferentiation. A combined analysis of the ubiquitinome with the corresponding WCP indicated that the dedifferentiation of PHCs led to an increase in nondegradative K27 ubiquitination. Functional analysis of the altered phosphoproteins suggested a significant enrichment in ferroptosis. In all, 404 proteins with both ubiquitination and phosphorylation were identified to be involved in critical metabolic events. Furthermore, Ptbp1, Hnrpd, Hnrnpu, and Srrm2 were identified as hub genes. Taken together, our data provide new insights into proteome dynamics during PHC dedifferentiation and potential targets to inhibit the dedifferentiation process.
Keywords: Ubiquitination Phosphoproteome Proteome Dedifferentiation Primary hepatocytes
Title Author Date Type Operation
ROLE OF NITROGEN SENSING AND ITS INTEGRATIVE SIGNALING PATHWAYS IN SHAPING ROOT SYSTEM ARCHITECTURE
Journal Article
Employing electricity-consumption monitoring systems and integrative time-series analysis models: A case
Seiya MAKI, Shuichi ASHINA, Minoru FUJII, Tsuyoshi FUJITA, Norio YABE, Kenji UCHIDA, Gito GINTING, Rizaldi BOER, Remi CHANDRAN
Journal Article
Development Strategy of Chinese and Western Integrative Medicine Under New Circumstances
Wang Conghui, Feng Zhe, Yin Zhiwei, Li Shuang, Chen Xiangmei
Journal Article
The Overall Development Strategy Research of “Internet Plus” Action Plan
Chen Zuoning,Li Bohu,Chai Xudong,Hou Baocun,Liu Yang,Chen Lei and Cheng Lin
Journal Article