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Multiple effects of grape seed polyphenolics to prevent metabolic diseases

Torey ARVIK, Hyunsook KIM, James SEIBER, Wallace YOKOYAMA

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 351-361 doi: 10.15302/J-FASE-2018235

Abstract: Animal models of obesity consistently show that grape seed procyanidins prevent increases in body andThe mechanisms are not clear because the oral intake of procyanidins results in pleiotropic interactionsProcyanidins also bind bile acids and reduce intestinal permeability to inflammatory bacterial cell wallProcyanidins are not degraded or metabolized until reaching the lower gut where they can be metabolizedThe review examines the different pleiotropic effects of grape seed procyanidins that have a significant

Keywords： grape seed     obesity     procyanidins     high fat     microbiota     animal models    

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Multiple effects of grape seed polyphenolics to prevent metabolic diseases

Torey ARVIK, Hyunsook KIM, James SEIBER, Wallace YOKOYAMA

Journal Article