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Special issue: Advances and prospect of engineering management

Lieyun DING, Heng LI

Frontiers of Engineering Management 2017, Volume 4, Issue 1, Pages 1-3 doi: 10.15302/J-FEM-2017102

Abstract:

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Recent advances in systemic lupus erythematosus and microbiota: from bench to bedside

Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 686-700 doi: 10.1007/s11684-022-0957-7

Abstract: In this review, the latest research about the role and mechanisms of microbiota in SLE and the advances

Keywords： systemic lupus erythematosus microbiota biotherapy

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An overview and recent advances in electrocatalysts for direct seawater splitting

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 6, Pages 1408-1426 doi: 10.1007/s11705-021-2102-6

Abstract: In comparison to pure water, seawater is widely accepted as an unlimited resource. The direct seawater splitting is economical and eco-friendly, but the key challenges in seawater, especially the chlorine-related competing reactions at the anode, seriously hamper its practical application. The development of earth-abundant electrocatalysts toward direct seawater splitting has emerged as a promising strategy. Highly efficient electrocatalysts with improved selectivity and stability are of significance in preventing the interference of side reactions and resisting various impurities. This review first discusses the macroscopic understanding of direct seawater electrolysis and then focuses on the strategies for rational design of electrocatalysts toward direct seawater splitting. The perspectives of improved electrocatalysts to solve emerging challenges and further development of direct seawater splitting are also provided.

Keywords： seawater splitting electrocatalysts oxygen evolution reaction hydrogen evolution reaction chlorine chemistry

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Emerging immunological strategies: recent advances and future directions

Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 805-828 doi: 10.1007/s11684-021-0886-x

Abstract: Immunotherapy plays a compelling role in cancer treatment and has already made remarkable progress. However, many patients receiving immune checkpoint inhibitors fail to achieve clinical benefits, and the response rates vary among tumor types. New approaches that promote anti-tumor immunity have recently been developed, such as small molecules, bispecific antibodies, chimeric antigen receptor T cell products, and cancer vaccines. Small molecule drugs include agonists and inhibitors that can reach the intracellular or extracellular targets of immune cells participating in innate or adaptive immune pathways. Bispecific antibodies, which bind two different antigens or one antigen with two different epitopes, are of great interest. Chimeric antigen receptor T cell products and cancer vaccines have also been investigated. This review explores the recent progress and challenges of different forms of immunotherapy agents and provides an insight into future immunotherapeutic strategies.

Keywords： cancer immunotherapy bispecific antibodies small molecules chimeric antigen receptor T therapy cancer vaccines

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Recent advances in cathode electrocatalysts for PEM fuel cells

Junliang ZHANG

Frontiers in Energy 2011, Volume 5, Issue 2, Pages 137-148 doi: 10.1007/s11708-011-0153-y

Abstract: This review article is focused on recent advances made in the kinetic-activity improvement on platinum

Keywords： proton exchange membrane fuel cells (PEMFCs) cathode electrocatalysts platinum oxygen reduction reaction (ORR)

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Recent advances of hydrogen production through particulate semiconductor photocatalytic overall water

Frontiers in Energy 2022, Volume 16, Issue 1, Pages 49-63 doi: 10.1007/s11708-022-0817-9

Abstract: Solar energy-driven photocatalytic water splitting has been investigated for decades to produce clean and renewable green hydrogen. In this paper, the cutting-edge research within the overall water splitting system is summarized from the one-step photocatalytic overall water splitting (POWS) system to the two-step system and the cocatalysts research in this field. In addition, the photocatalytic reaction engineering study is also reviewed which is crucial for future scale-up. This mini-review provides a picture of survey of recent progress of relevant overall water splitting system, with particular attention paid to material system and mechanistic breakthroughs, and highlights the challenge and opportunity of the current system.

Keywords： photocatalysis overall water splitting hydrogen

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Recent advances in the electrochemical oxidation water treatment: Spotlight on byproduct control

Yang Yang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1264-7

Abstract: In this mini-review, we will summarize the recent advances and provide perspectives to address the above

Keywords： Electrochemical water treatment Byproducts Perchlorate

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The advances of Sino-German new materials

Rongbiao Wang

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 3, Pages 327-328 doi: 10.1007/s11705-018-1748-1

Abstract:

Keywords： valign= top class= J_zhaiyao

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Recent advances in antimony removal using carbon-based nanomaterials: A review

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 4, doi: 10.1007/s11783-021-1482-7

Abstract:

• The synthesis and physicochemical properties of various CNMs are reviewed.

Keywords： Antimony Carbon nanomaterials Adsorption Membrane separation

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Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1, Pages 34-63 doi: 10.1007/s11705-021-2050-1

Abstract: H₂S is well-known as a colorless, acidic gas, with a notoriously rotten-egg smell. It was recently revealed that H₂S is also an endogenous signaling molecule that has important biological functions, however, most of its physiology and pathology remains elusive. Therefore, the enthusiasm for H₂S research remains. Fluorescence imaging technology is an important tool for H₂S biology research. The development of fluorescence imaging technology has realized the study of H₂S in subcellular organelles, facilitated by the development of fluorescent probes. The probes reviewed in this paper were categorized according to their chemical mechanism of sensing and were divided into three groups: H₂S reducibility-based probes, H₂S nucleophilicity-based probes, and metal sulfide precipitation-based probes. The structure of the probes, their sensing mechanism, and imaging results have been discussed in detail. Moreover, we also introduced some probes for hydrogen polysulfides.

Keywords： hydrogen sulfide fluorescent probe reducibility nucleophilicity copper sulfide precipitate hydrogen polysulfides

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Recent advances in SERS detection of perchlorate

Jumin Hao, Xiaoguang Meng

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 3, Pages 448-464 doi: 10.1007/s11705-017-1611-9

Abstract: Perchlorate has recently emerged as a widespread environmental contaminant of healthy concern. Development of novel detection methods for perchlorate with the potential for field use has been an urgent need. The investigation has shown that surface-enhanced Raman scattering (SERS) technique has great potential to become a practical analysis tool for the rapid screening and routine monitoring of perchlorate in the field, particularly when coupled with portable/handheld Raman spectrometers. In this review article, we summarize progress made in SERS analysis of perchlorate in water and other media with an emphasis on the development of SERS substrates for perchlorate detection. The potential of this technique for fast screening and field testing of perchlorate-contaminated environmental samples is discussed. The challenges and possible solutions are also addressed, aiming to provide a better understanding on the development directions in the research field.

Keywords： perchlorate SERS detection substrate modification nanostructure

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Recent advances, challenges, and perspectives on carbon capture

Frontiers of Environmental Science & Engineering 2024, Volume 18, Issue 6, doi: 10.1007/s11783-024-1835-0

Abstract: Recent advances in promising CCUS technologies are assessed.

Keywords： Carbon capture utilization and storage Visualization analysis Research hotspots and trends CO₂ capture technology

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Recent advances in cycloaddition of CO with epoxides: halogen-free catalysis and mechanistic insights

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12, Pages 1879-1894 doi: 10.1007/s11705-023-2354-4

Abstract: The atom-economical cycloaddition of CO₂ with epoxides to synthesize cyclic carbonates is a promising route for valuable utilization of CO₂. Halogenide such as alkali metal halides and quaternary ammonium salt have been developed as the efficient catalysts. However, the spilled halogen causes equipment corrosion and affects the product purity. To address these concerns, the halogen-free cycloaddition of CO₂ with epoxides has always been desired. In this review, we systematically discussed the halogen-free catalysis for cycloaddition of CO₂ with epoxides from the mechanistic insights, aiming to promote the development of efficient halogen-free catalysts. Two types of catalysts, i.e., alternatives of halogen nucleophiles for epoxide activation, and bifunctional catalysts with Lewis acid-base sites for synergistic activation of CO₂ and epoxides are summarized and emphasized. Specially, metal oxides as the potential halogen-free catalysts are highlighted due to their flexible acid-base sites for synergistic activation of CO₂ and epoxides, facile preparation, and low cost.

Keywords： carbon dioxide halogen-free catalysis cyclic carbonate mechanistic insight

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Current advances in the elimination of hepatitis B in China by 2030

Shuye Zhang, Fusheng Wang, Zheng Zhang

Frontiers of Medicine 2017, Volume 11, Issue 4, Pages 490-501 doi: 10.1007/s11684-017-0598-4

Abstract:

With its 78 million chronic carriers, hepatitis B virus (HBV) infection is still one of the leading public health challenges in China. Over the last two decades, China has made great progress on the prevention of HBV transmission through national vaccination programs. Zero transmission from mother to infant has been proposed as the current goal. Available anti-HBV therapy is efficacious in suppressing HBV replication; however, it fails to completely cure patients with chronic hepatitis B and even requires lifelong treatment. To reduce the costs and improve the efficacy, several trials have been recently conducted in China to optimize the current anti-HBV managements. Novel biomarkers were identified to predict treatment outcomes, and new promising treatment strategies were developed. Reports also indicate that coinfections of HBV with other hepatotropic viruses and human immunodeficiency virus are common in China and cause severe liver diseases, which should be recognized early and treated properly. Work is still needed to eliminate hepatitis B in China by 2030.

Keywords： HBV CHB biomarker functional cure coinfection