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Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG
Mengmeng Pan,Qiyao Zhang,Ping Liu,Jinyan Huang,Yueying Wang,Saijuan Chen
Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 410-419 doi: 10.1007/s11684-016-0489-0
NUP98 fuses with approximately 34 different partner genes via translocation in hematologicalWe previously reported the fusion protein NUP98-IQ motif containing G (IQCG) in a myeloid/T lymphoidHerein, we demonstrated the association of NUP98-IQCG with CRM1, and found that NUP98-IQCG expressionMoreover, IQCG could be entrapped in the nucleus by NUP98-IQCG, and the fusion protein interacts withNUP98-IQCG.
Keywords： NUP98-IQCG nuclear export NF-κB CRM1
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