多囊卵巢综合征无排卵的胰岛素信号和雄激素合成的新遗传风险和代谢特征

工程（英文） ›› 2023, Vol. 23 ›› Issue (4) : 103 -111. DOI: 10.1016/j.eng.2022.08.013

吴效科 ^a^,^b^,^* ,
黄志超 ^c^,^d^,^* ,
曹义娟 ^e^,^* ,
李建 ^f ,
李志强 ^g^,^h ,
马红丽 ^a ,
高敬书 ^a ,
常惠 ^a ,
张多加 ^a ,
丛晶 ^a ,
王宇 ^a ,
吴奇 ⁱ ,
Xiaoxiao Han ^j^,^k ,
Pui Wah Jacqueline Chung ^c ,
Yiran Li ^c ,
Xu Zheng ^c ,
Lingxi Chen ^l ,
Lin Zeng ^m ,
Astrid Borchert ⁿ ,
Hartmut Kuhn ⁿ ,
Zi-Jiang Chen ^o ,
Ernest Hung Yu Ng ^p ,
Elisabet Stener-Victorin ^q ,
张和平 ^r ,
Richard S. Legro ^s ,
Ben Willem J. Mol ^t^,^u ,
师咏勇 ^h

作者信息 +

^a The First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China

^b Department of Reproductive Medicine, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin 150030, China

^c Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong 999077, China

^d Reproduction and Development Laboratory, Li Ka Shing Institute of Health Sciences & Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine, The Chinese University of Hong Kong, Hong Kong 999077, China

^e Center for Reproductive Medicine, Xuzhou Central Hospital, Xuzhou 221009, China

^f Department of Obstetrics and Gynecology, The Affiliated Hospital of Gui Zhou Medical University, Guiyang 550004, China

^g Biomedical Sciences Institute, The Affiliated Hospital of Qingdao University, Qingdao 266000, China

^h Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Bio-X Institutes, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China

ⁱ Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200001, China

^j Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai 200001, China

^k Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200001, China

^l Department of Computer Sciences, City University of Hong Kong, Hong Kong 999077, China

^m Shanghai NewCore Biotechnology Co., Ltd., Shanghai 200240, China

ⁿ Institute of Biochemistry, Charité—University Medicine Berlin, Berlin 10117, Germany

^o Center for Reproductive Medicine, Shandong University, Jinan 250001, China

^p Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong 999077, China

^q Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm 17177, Sweden

^r Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520, USA

^s Department of Obstetrics and Gynecology, Pennsylvania State University, Hershey, PA 17033, USA

^t Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre, Clayton, VIC 3168, Australia

^u Aberdeen Centre for Women’s Health Research, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK

^* These authors contributed equally to this work.

收起

Novel Genetic Risk and Metabolic Signatures of Insulin Signaling and Androgenesis in the Anovulation of Polycystic Ovary Syndrome

Xiaoke Wu ^a^,^b^,^* ,
Chi Chiu Wang ^c^,^d^,^* ,
Yijuan Cao ^e^,^* ,
Jian Li ^f ,
Zhiqiang Li ^g^,^h ,
Hongli Ma ^a ,
Jingshu Gao ^a ,
Hui Chang ^a ,
Duojia Zhang ^a ,
Jing Cong ^a ,
Yu Wang ^a ,
Qi Wu ⁱ ,
Xiaoxiao Han ^j^,^k ,
Pui Wah Jacqueline Chung ^c ,
Yiran Li ^c ,
Xu Zheng ^c ,
Lingxi Chen ^l ,
Lin Zeng ^m ,
Astrid Borchert ⁿ ,
Hartmut Kuhn ⁿ ,
Zi-Jiang Chen ^o ,
Ernest Hung Yu Ng ^p ,
Elisabet Stener-Victorin ^q ,
Heping Zhang ^r ,
Richard S. Legro ^s ,
Ben Willem J. Mol ^t^,^u ,
Yongyong Shi ^h

Author information +