具有超高K+选择性的传输通道对生物起着至关重要的作用，但构建具有良好K+选择性和渗透性的离子通道仍然是一项挑战。在本次研究中，一种基于MXene（Ti3C2Tx）层状通道的不对称双层膜展现出了惊人的马太效应：放大K+的优先传输，从而实现出色的K+分离性能。由于优先亲和效应，1-氮杂-18-冠醚-6 改性的识别层会选择K+离子，随后基于限域效应，K+离子会以水合离子的形式通过促进层快速传输。K+优先占据冠醚，阻碍了其他非选择性离子（如Na+）进入识别层。基于MXene (Ti3C2Tx)的马太膜具有0.1-0.2 mol∙m-2∙h-1的高K+渗透率，且K+/Na+选择性高达5-9。深入研究了马太膜的离子分离机理，探讨了马太放大效应对K+筛分的本质机理，即膜内识别层和促进层的精确匹配决定了K+的快速渗透和良好的选择性。本研究所构建的马太膜的非对称结构是了解离子通道精确快速离子转运的生物学功能的关键，它将指导设计和合成高性能人工离子通道或膜材料。

Transport channels with ultrahigh K⁺ selectivity over other ions play a crucial role for living beings, but constructing ionic channels with promising K⁺ selectivity and permeability remains a challenge. Here, an asymmetric bilayer membrane based on MXene (Ti₃C₂T_x) lamellar channels consisting of a recognition layer (RL) on top of an enhancement layer (EL) exhibits an amazing Matthew effect: amplification of the preferred transport of K⁺, resulting in an excellent K⁺-separation performance. The K⁺ ion is selected by the 1-aza-18-crown-6 ether-modified RL, owing to preferential affinity energy, and then rapidly transported as a hydrated ion through the EL, based on the confinement effect. Other undesired ions such as Na⁺ are hindered from entering the RL by the preferred K⁺ occupation of the crown ether. The MXene (Ti₃C₂T_x)-based Matthew membrane presents high K⁺-permeation rates of 0.1-0.2 mol∙m⁻²∙h⁻¹, with a significant K⁺/Na⁺ selectivity of 5-9. The molecular separation mechanism of the Matthew membrane is investigated deeply to explore the nature of the Matthew amplification effect on K⁺ sieving, where the precise matching of the RL and EL within the membrane governs the fast K⁺ permeation with good selectivity. The asymmetric structure of our Matthew membrane is the key to understanding the biological function of ion channels for precise and fast ion transport, which will guide us in the creation of artificial ion channels or membranes.