水稻RBRL蛋白——三重抗病毒网络的枢纽

Jing Liu; Sheng Wang; Wishwajith Kandegama; Xin Xie; Xiangyang Li

doi:10.1016/j.eng.2026.02.032

工程（英文） ›› 2026, Vol. 65 ›› Issue (10) : 19 -21. DOI: 10.1016/j.eng.2026.02.032

水稻RBRL蛋白——三重抗病毒网络的枢纽

Jing Liu ^a^,^# ,
Sheng Wang ^a^,^# ,
Wishwajith Kandegama ^b ,
Xin Xie ^c^,^* ,
Xiangyang Li ^a^,^*

作者信息 +

The Rice RBRL Protein: The Hub of a Triple Antivirus Network

Jing Liu ^a^,^# ,
Sheng Wang ^a^,^# ,
Wishwajith Kandegama ^b ,
Xin Xie ^c^,^* ,
Xiangyang Li ^a^,^*

Author information +

文章历史 +

PDF

Abstract

Upon virus entry into rice cells, facilitated by insect vectors, the viral CP is recognized and bound by the RING-type ubiquitin ligase RBRL, which subsequently activates its E3 ubiquitin ligase activity. This activation results in the ubiquitination and subsequent degradation of NINJA3, a known inhibitor of the jasmonic acid (JA) signaling pathway. Degradation of NINJA3 alleviates the inhibitor’s repression of the JA signaling pathway, facilitating pathway activation, which leads to the upregulation of genes responsible for JA biosynthesis and the expression of downstream antiviral factors, including AGO18. This mechanism also inhibits viral replication through enhanced RNA interference, ultimately enabling rice plants to mount a robust antiviral defense.

引用本文

引用格式 ▾

[Author(id=1325147267758142201, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1325147267816862464, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, authorId=1325147267758142201, language=EN, stringName=Jing Liu, firstName=Jing, middleName=null, lastName=Liu, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^a^,^#, address=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1325147267577787119, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, xref=a, ext=[AuthorCompanyExt(id=1325147267590370032, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, companyId=1325147267577787119, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China)])]), Author(id=1325147267862999813, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1325147267930108683, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, authorId=1325147267862999813, language=EN, stringName=Sheng Wang, firstName=Sheng, middleName=null, lastName=Wang, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^a^,^#, address=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1325147267577787119, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, xref=a, ext=[AuthorCompanyExt(id=1325147267590370032, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, companyId=1325147267577787119, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China)])]), Author(id=1325147267976246031, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1325147268030771985, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, authorId=1325147267976246031, language=EN, stringName=Wishwajith Kandegama, firstName=Wishwajith, middleName=null, lastName=Kandegama, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^b, address=^b Department of Horticulture and Landscape Gardening, Faculty of Agriculture and Plantation Management, Wayamba University of Sri Lanka, Kurunegala 60170, Sri Lanka, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1325147267640701682, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, xref=b, ext=[AuthorCompanyExt(id=1325147267653284596, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, companyId=1325147267640701682, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^b Department of Horticulture and Landscape Gardening, Faculty of Agriculture and Plantation Management, Wayamba University of Sri Lanka, Kurunegala 60170, Sri Lanka)])]), Author(id=1325147268076909331, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=ippxiexin@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1325147268135629592, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, authorId=1325147268076909331, language=EN, stringName=Xin Xie, firstName=Xin, middleName=null, lastName=Xie, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^c^,^*, address=^c College of Agriculture, Guizhou University, Guiyang 550025, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1325147267699421942, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, xref=c, ext=[AuthorCompanyExt(id=1325147267716199159, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, companyId=1325147267699421942, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^c College of Agriculture, Guizhou University, Guiyang 550025, China)])]), Author(id=1325147268177572637, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=xyli1@gzu.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1325147268236292900, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, authorId=1325147268177572637, language=EN, stringName=Xiangyang Li, firstName=Xiangyang, middleName=null, lastName=Li, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^a^,^*, address=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1325147267577787119, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, xref=a, ext=[AuthorCompanyExt(id=1325147267590370032, tenantId=1045748351789510663, journalId=1155139928190095384, articleId=1248628525532311649, companyId=1325147267577787119, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^a State Key Laboratory of Green Pesticide, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China)])])] Jing Liu,Sheng Wang,Wishwajith Kandegama,Xin Xie,Xiangyang Li. 水稻RBRL蛋白——三重抗病毒网络的枢纽[J]. 工程（英文）, 2026, 65(10): 19-21 DOI:10.1016/j.eng.2026.02.032