自20世纪90年代西安交通大学机械工程学院提出生物制造的概念，提出以工程方法解决医学问题以来，在20多年与医学、材料和生物学等学科专家的密切合作中，已在骨与关节、肝脏、肠道、大脑等器官的人工内植入物研究上取得了进展。重点介绍和总结了定制化人工假体、活性人工骨和关节以及组织工程化肝脏等制造技术的研究工作与成果，探索其中的问题与发展前景。

The concept of biofabrication was provided by School of Mechanical Engineering, Xi'an Jiaotong University since the 1990s. Using the engineering methods to solve the medical issues, we have made some achievements and development on the implants for bone and cartilage, liver, intestinal tissue as well as brain. This paper emphasized on the lastest research work of the customized artificial prosthesis, bioactive bone and joint, and tissue engineered liver in our laboratory, which was corporated with the experts and sciencists of various areas from medicine, biology as well as materials for more than 20 years. Furthermore, it also explored the problems and prospects for the development and application of biofabrication.

女，广东潮州市人，副教授，研究方向为生物制造