Neutron Capture Therapy (NCT) & In-hospital neutron irradiator (IHNI)—a new technology on binary targeting radiation therapy of cancer

Zhou Yongmao

中国工程科学 ›› 2009, Vol. 11 ›› Issue (4) : 2 -21.

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中国工程科学 ›› 2009, Vol. 11 ›› Issue (4) : 2 -21.

Neutron Capture Therapy (NCT) & In-hospital neutron irradiator (IHNI)—a new technology on binary targeting radiation therapy of cancer

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Neutron Capture Therapy (NCT) & InHospital Neutron Irradiator (IHNI)—a new technology on binary targeting radiation therapy of cancer

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摘要

BNCT is finally becoming “a new option against cancer”. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantification and accuracy upon radiation dosimetry evaluation in clinical trials. Furthermore, that is long anticipation on hospital base neutron sources. It includes dedicated new NCT reactor, accelerator based neutron sources, and isotope source facilities. In addition to reactors, so far, the technology of other types of sources for clinical trials is not yet completely proven. The In-Hospital Neutron Irradiator specially designed for NCT, based on the MNSR successfully developed by China, can be installed inside or near the hospital and operated directly by doctors. The Irradiator has two neutron beams for respective treatment of the shallow and deep tumors. It is expected to initiate operation in the end of this year. It would provide a safe, low cost, and effective treatment tool for the NCT routine application in near future.

Abstract

BNCT is finally becoming “a new option against cancer”. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantification and accuracy upon radiation dosimetry evaluation in clinical trials. Furthermore, that is long anticipation on hospital base neutron sources. It includes dedicated new NCT reactor, accelerator based neutron sources, and isotope source facilities. In addition to reactors, so far, the technology of other types of sources for clinical trials is not yet completely proven. The InHospital Neutron Irradiator specially designed for NCT, based on the MNSR successfully developed by China, can be installed inside or near the hospital and operated directly by doctors. The Irradiator has two neutron beams for respective treatment of the shallow and deep tumors. It is expected to initiate operation in the end of this year. It would provide a safe, low cost, and effective treatment tool for the NCT routine application in near future.

关键词

Neutron Capture Therapy / boron compound / radiation dosimetry / neutron beam / in-hospital neutron irradiator

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Neutron Capture Therapy / boron compound / radiation dosimetry / neutron beam / inhospital neutron irradiator

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Zhou Yongmao Neutron Capture Therapy (NCT) & In-hospital neutron irradiator (IHNI)—a new technology on binary targeting radiation therapy of cancer[J]. 中国工程科学, 2009, 11(4): 2-21 DOI:

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