在介绍RNA病毒结构、生殖、复制和转录的基础上，综述了抗病毒策略，其中包括抗SARS药物设计，RNA干扰，DNA疫苗释放系统，调控蛋白与糖胺聚糖衍生物或类似物相互作用，天然药物及肺泡组织工程等。这些实例涵盖了RNA病毒与蛋白质、DNA及多糖等生物材料的相互作用。生物材料作为基质或载体正在向细胞或/和基因活化的第三代生物材料发展，可望在抗病毒中发挥作用。

The structure, reproduction, replication and transcription of RNA viruses were introduced. Antivirus strategies including design of anti - SARS drugs, RNA interference, DNA vaccine delivery system, modulation of interaction of envelop glycoprotein with glycosanminoglycan derivatives or analogues, natural herbal medicine and alveolus tissue engineering were reviewed. These examples imply the interactions of RNA viruses with proteins, DNA, and polysaccharides. Nowadays biomaterials matrixes or vectors are developing toward the third generation, i.e. cell or/and activated ones. It is sure that biomaterials will play a crucial role in fighting against SARS viruses and the like.