用于医学诊断和治疗的质子回旋加速器

樊明武

中国工程科学 ›› 2000, Vol. 2 ›› Issue (12) : 9 -15.

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中国工程科学 ›› 2000, Vol. 2 ›› Issue (12) : 9 -15.
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用于医学诊断和治疗的质子回旋加速器

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Medical Cyclotron Used for Diagnostic or Therapy

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摘要

在许多医院都安装了生产短寿命放射性同位素的回旋加速器,但用于质子治疗的回旋加速器还处于起步阶段。质子治疗可以达到精确的幅照剂量分布,质子能量决定了穿透深度,因而产生的能量释放点可以精确控制,技术先进。由于质子束传播的线形度好,引起的横向二次散射小,肿瘤前端的健康组织接受的剂量很小,在其周围和之后的组织几乎就没有照射剂量,因此质子束治疗是一种非常有效的方法。束流传输到治疗房间的效率,束流的能量控制、强度及位置的稳定性,快速而精确的改变束流参数来满足临床需要等,都是关键。开发安装于医院的并可满足病人实际需要的质子治疗回旋加速器,包括束流输运系统和一系列的控制系统都相当复杂,文章提出了用于该目的的概念框图和建议。

Abstract

Cyclotron operated within a hospital to deliver radiation to produce short life radioactive isotopes for diagnostic purpose is used in many hospitals. But cyclotron used for proton therapy is just at beginning. Proton beam therapy is a technologically advanced approach since it achieves precise radiation dose distribution. As the depth of penetration is a function of its energy, the point of energy release of the proton can be very precisely determined. The path of the proton beam is linear and causes very little secondary lateral scatter. Healthy tissues upstream from the tumor receive only a small dose and those located around the tumor and behind receive virtually none. Thus proton beam therapy is the most effective method. On the other hand, the cyclotron must be reliable, and the beam must be stable to ensure patient´s safety since the proton beam is used directly. Efficiency of beam delivery to the treatment rooms, raster scanning techniques to ensure the correct control of beam energy, intensity, and position stability, rapid and precise flexibility in changing beam parameter are also essential for satisfying clinical needs. The design efforts for developing a hsopital-based medical therapy cyclotron including the clinical beam delivery systems and integrated control system are really complex, and are less well developed than patients real need. A conception scheme for the purpose is proposed.

关键词

回旋加速器 / 正电子断层照相 / 短寿命放射性同位素 / 质子束治疗

Key words

cyclotron / positron emission tomography / short life radioisotope / proton beam therapy

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樊明武 用于医学诊断和治疗的质子回旋加速器[J]. 中国工程科学, 2000, 2(12): 9-15 DOI:

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