The conceptual study on the accelerator driven system (ADS) that lasted for about five years ended in 1999 in China. As one project of the National Basic Research Program of China (973 Program) in the energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five-year-program of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. The China Institute of Atomic Energy (CIAE), the Institute of High Energy Physics (IHEP), the Institute of Heavy Ion Physics in Peking University (PKU-IHIP) and other institutions jointly carried out the research. The research activities were focused on HPPA physics and technology, reactor physics of external source driven sub-critical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV was built. In reactor physics study, a series of neutron multiplication experimental study has been carried out and still being done. The VENUS facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. It s a zero power sub-critical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator. The theoretical, experimental and simulation study on nuclear data, material properties and nuclear fuel circulation related to ADS is carrying on to provide the database for ADS system analysis. The main results on ADS related researches will be reported.