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Type 2 diabetic patients with non-alcoholic fatty liver disease exhibit significant haemorheological
Hui Dong, Fu’er Lu, Nan Wang, Xin Zou, Jingjing Rao
《医学前沿(英文)》 2011年 第5卷 第3期 页码 288-293 doi: 10.1007/s11684-011-0127-9
关键词: diabetes mellitus type 2 haemorheology non-alcoholic fatty liver disease
《农业科学与工程前沿(英文)》 2022年 第9卷 第2期 页码 177-186 doi: 10.15302/J-FASE-2021421
A range of plant species produce root exudates that inhibit ammonia-oxidizing microorganisms. This biological nitrification inhibition (BNI) capacity can decrease N loss and increase N uptake from the rhizosphere. This study sought evidence for the existence and magnitude of BNI capacity in canola ( Brassica napus). Seedlings of three canola cultivars, Brachiaria humidicola(BNI positive) and wheat ( Triticum aestivum) were grown in a hydroponic system. Root exudates were collected and their inhibition of the ammonia oxidizing bacterium, Nitrosospira multiformis, was tested. Subsequent pot experiments were used to test the inhibition of native nitrifying communities in soil. Root exudates from canola significantly reduced nitrification rates of both N. multiformis cultures and native soil microbial communities. The level of nitrification inhibition across the three cultivars was similar to the well-studied high-BNI species B. humidicola. BNI capacity of canola may have implications for the N dynamics in farming systems and the N uptake efficiency of crops in rotational farming systems. By reducing nitrification rates canola crops may decrease N losses, increase plant N uptake and encourage microbial N immobilization and subsequently increase the pool of organic N that is available for mineralization during the following cereal crops.
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《医学前沿(英文)》 2015年 第9卷 第3期 页码 331-343 doi: 10.1007/s11684-015-0409-8
MicroRNAs (miRNAs), an important class of small non-coding RNAs, regulate gene expression at the post-transcriptional level. miRNAs are involved in a wide range of biological processes and implicated in different diseases, including cancers. In this study, miRNA profiling and qRT-PCR validation revealed that miR-142-3p and miR-142-5p were significantly downregulated in hepatocellular carcinoma (HCC) and their expression levels decreased as the disease progressed. The ectopic expression of miR-142 significantly reduced HCC cell migration and invasion. Overexpression of either miR-142-3p or miR-142-5p suppressed HCC cell migration, and overexpression of both synergistically inhibited cell migration, which indicated that miR-142-3p and miR-142-5p may cooperatively regulate cell movement. miR-142-3p and miR-142-5p, which are mature miRNAs derived from the 3′- and 5′-strands of the precursor miR-142, target distinct pools of genes because of their different seed sequences. Pathway enrichment analysis showed a strong association of the putative gene targets of miR-142-3p and miR-142-5p with several cell motility-associated pathways, including those regulating actin cytoskeleton, adherens junctions, and focal adhesion. Importantly, a number of the putative gene targets were also significantly upregulated in human HCC cells. Moreover, overexpression of miR-142 significantly abrogated stress fiber formation in HCC cells and led to cell shrinkage. This study shows that mature miR-142 pairs collaboratively regulate different components of distinct signaling cascades and therefore affects the motility of HCC cells.
关键词: hepatocellular carcinoma microRNA metastasis cytoskeletal reorganization
Preparation and characterization of SO42-/TiO2 and S2O82-/TiO2 catalysts
MA Xuedan, GUO Daishi, JIANG Qizhong, MA Zifeng, MA Zhengfei, YE Weidong, LI Chunbo
《化学科学与工程前沿(英文)》 2007年 第1卷 第1期 页码 45-49 doi: 10.1007/s11705-007-0009-5
关键词: exhibit Different persulfate adsorption-desorption catalytic
标题 作者 时间 类型 操作
Type 2 diabetic patients with non-alcoholic fatty liver disease exhibit significant haemorheological
Hui Dong, Fu’er Lu, Nan Wang, Xin Zou, Jingjing Rao
期刊论文
ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING
期刊论文
MicroRNA-142-3p and microRNA-142-5p are downregulated in hepatocellular carcinoma and exhibit synergistic
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期刊论文