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《能源前沿(英文)》 2023年 第17卷 第5期 页码 678-691 doi: 10.1007/s11708-022-0859-z
关键词: gasoline compression ignition injection strategy fuel stratification high efficiency high load
Comparison of prechilling stratification and sulfuric acid scarification on seed germination of
Nan WANG, Jing GAO, Suiqi ZHANG, Feng YAN
《农业科学与工程前沿(英文)》 2017年 第4卷 第2期 页码 220-227 doi: 10.15302/J-FASE-2017146
关键词: base water potential data analysis method embryo growth germination
《医学前沿(英文)》 2022年 第16卷 第6期 页码 957-968 doi: 10.1007/s11684-021-0910-1
关键词: skin and soft tissue infections hematopoietic stem cell transplantation risk stratification system mortality
Chaotic behavior of LNG after stratification in main stream region of storage tank
WANG Jingjing, MA Xiaoqian
《能源前沿(英文)》 2008年 第2卷 第4期 页码 514-518 doi: 10.1007/s11708-008-0076-4
关键词: Runge-Kutta non-linear corresponding temperature addition
Structure creation in earthen construction materials: information from dry soil mixtures
Christopher BECKETT, Charles AUGARDE
《结构与土木工程前沿(英文)》 2011年 第5卷 第2期 页码 151-159 doi: 10.1007/s11709-011-0109-7
关键词: rammed earth stratification particle size distribution pore size distribution
Zhijun PENG ,
《能源前沿(英文)》 2009年 第3卷 第3期 页码 353-358 doi: 10.1007/s11708-009-0035-8
关键词: charge stratification SI engine lean-burn combustion NO emission
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
《医学前沿(英文)》 2010年 第4卷 第4期 页码 356-362 doi: 10.1007/s11684-010-0220-5
Yang YU, Wanhua SU,
《能源前沿(英文)》 2010年 第4卷 第2期 页码 269-279 doi: 10.1007/s11708-009-0046-5
关键词: PCCI fuel stratification multi-pulse injection ignition
余英
《中国工程科学》 2013年 第15卷 第9期 页码 27-32
三峡升船机船厢室段塔柱承重结构的横梁混凝土浇筑施工难度大、复杂性高、无成熟技术可供参考。本文结合三峡升船机塔柱横梁混凝土浇筑的结构特点以及施工特性,总结了三峡升船机续建工程顶部横梁混凝土的施工技术,即采用分层、分块浇筑的办法,通过科学计算后进行合理的施工机械布置和浇筑施工管理,以保证塔柱横梁混凝土的施工质量。通过对贝雷架支撑系统的监测结果分析可知,贝雷架支撑系统的应力变形、挠度变形以及排架变形均满足施工承载要求,筒体位移亦满足技术要求,贝雷架支撑系统稳定、安全。三峡升船机塔柱横梁混凝土施工实践证明了本技术方案的有效性与可靠性,亦可为类似工程的施工组织设计与现场实施工作提供一定的参考。
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
《环境科学与工程前沿(英文)》 2011年 第5卷 第1期 页码 48-56 doi: 10.1007/s11783-011-0305-7
关键词: ammonium-rich wastewater membrane biofilm reactor nitrification redox stratification shortcut nitrogen removal
null
《医学前沿(英文)》 2016年 第10卷 第1期 页码 104-110 doi: 10.1007/s11684-016-0432-4
Advances in next-generation sequencing and bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oral squamous cell carcinoma (OSCC). Sophisticated preclinical models that fully represent intra- and inter-tumoral heterogeneity are required to understand the molecular diversity of cancer and achieve the goal of personalized therapies. Patient-derived xenograft (PDX) models generated from human tumor samples that can retain the histological and genetic features of their donor tumors have been shown to be the preferred preclinical tool in translational cancer research compared with other conventional preclinical models. Specifically, genetically well-defined PDX models can be applied to accelerate targeted antitumor drug development and biomarker discovery. Recently, we have successfully established and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer research. In this paper, we discuss the establishment, characterization, and preclinical applications of the PDX models. In particular, we focus on the classification and applications of the PDX models based on validated annotations, including clinicopathological features, genomic profiles, and pharmacological testing information. We also explore the translational value of this well-annotated PDX panel in the development of co-clinical trials for patient stratification and treatment optimization in the near future. Although various limitations still exist, this preclinical approach should be further tested and improved.
关键词: patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral squamous cell carcinoma
null
《医学前沿(英文)》 2013年 第7卷 第4期 页码 477-485 doi: 10.1007/s11684-013-0284-0
This study aims to construct a logistically derived additive score for predicting in-hospital mortality risk in Chinese patients undergoing coronary artery bypass surgery (CABG). Data from 9839 consecutive CABG patients in 43 Chinese centers were collected between 2007 and 2008 from the Chinese Coronary Artery Bypass Grafting Registry. This database was randomly divided into developmental and validation subsets (9:1). The data in the developmental dataset were used to develop the model using logistic regression. Calibration and discrimination characteristics were assessed using the validation dataset. Thresholds were defined for each model to distinguish different risk groups. After excluding 275 patients with incomplete information, the overall mortality rate of the remaining 9564 patients was 2.5%. The SinoSCORE model was constructed based on 11 variables: age, preoperative NYHA stage III or IV, chronic renal failure, extracardiac arteriopathy, chronic obstructive pulmonary disease, preoperative atrial fibrillation or flutter (within 2βweeks), left ventricular ejection fraction, other elective surgery, combined valve procedures, preoperative critical state, and BMI. In the developmental dataset, calibration using a Hosmer-Lemeshow (HL) test was at =β0.44 and discrimination based on the area under the receiver operating characteristic curve (ROC) was 0.80. In the validation dataset, the HL test was at =β0.34 and the area under the ROC (AUC) was 0.78. A logistically derived additive model for predicting in-hospital mortality among Chinese patients undergoing CABG was developed based on the most up-to-date multi-center data from China.
关键词: coronary artery bypass grafting risk stratification in-hospital mortality
Xiaofeng ZHANG,Xu ZHANG,Guanghe LI
《环境科学与工程前沿(英文)》 2015年 第9卷 第2期 页码 269-278 doi: 10.1007/s11783-014-0672-y
关键词: moisture vertical distribution moisture temporal variation texture stratification irrigation meteorological forcing urban landscape
标题 作者 时间 类型 操作
A methodology for regulating fuel stratification and improving fuel economy of GCI mode via double main-injection
期刊论文
Comparison of prechilling stratification and sulfuric acid scarification on seed germination of
Nan WANG, Jing GAO, Suiqi ZHANG, Feng YAN
期刊论文
Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem cell
期刊论文
Chaotic behavior of LNG after stratification in main stream region of storage tank
WANG Jingjing, MA Xiaoqian
期刊论文
Structure creation in earthen construction materials: information from dry soil mixtures
Christopher BECKETT, Charles AUGARDE
期刊论文
Numerical simulation of charge stratifications to improve combustion and NO formation of lean-burn SI engines
Zhijun PENG ,
期刊论文
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
期刊论文
Effect of distributions of fuel concentration and temperature on ignition processes in a diesel PCCI combustion
Yang YU, Wanhua SU,
期刊论文
Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich wastewater
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
期刊论文
Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization
null
期刊论文
SinoSCORE: a logistically derived additive prediction model for post-coronary artery bypass grafting in-hospital mortality in a Chinese population
null
期刊论文